METHODS FOR INDUCING ADIPOSE TISSUE REMODELING USING RNAi THERAPEUTICS

    公开(公告)号:WO2023092142A1

    公开(公告)日:2023-05-25

    申请号:PCT/US2022/080330

    申请日:2022-11-22

    申请人: SIRNAOMICS, INC.

    摘要: Methods are provided for inducing the remodeling of adipose tissue in patients to improve health as well as the aesthetic appearance of adipose tissue. RNAi techniques are used with transforming growth factor beta 1 (TGF-β1) and cyclooxygenase 2 (Cox2), both of which have been implicated in disease progression and negative remodeling effects on skin tissues. Administration of two siRNAs targeting TGF-β1 and Cox2 in a single nanoparticle formulation permits entry of the siRNAs into the same cells at the same time and the silencing of target genes in these cells results in favorable remodeling of adipose tissue.

    PORTABLE FLUID FILTERING APPARATUS
    2.
    发明申请

    公开(公告)号:WO2023092125A1

    公开(公告)日:2023-05-25

    申请号:PCT/US2022/080248

    申请日:2022-11-21

    申请人: WATER TECH, LLC

    摘要: A portable fluid filtering apparatus includes a debris chamber having an exhaust port; a rotor that draws in a fluid from outside the debris chamber to the exhaust port; a filter positioned between the exhaust port and the rest of the debris chamber; an intake port in fluid communication with the debris chamber and wherein the rotor draws the fluid into the debris chamber through the intake port; and a drive system configured to rotate the rotor that includes a drive shaft connected to the rotor, a motor to rotate the drive shaft, and a power source for the motor.

    SOCKET STORAGE DEVICE
    3.
    发明申请

    公开(公告)号:WO2023092085A1

    公开(公告)日:2023-05-25

    申请号:PCT/US2022/080162

    申请日:2022-11-18

    发明人: HERRITZ, Devin W.

    IPC分类号: B25H3/02

    摘要: Various socket storage systems are shown. The socket storage system includes one or more storage rails, socket holders of various sizes and socket posts. The socket storage rail includes a plurality of dovetail attachments allowing for selectively coupling between socket storage rails. The socket holders are adjustable relative to the socket storage rail for additional customization.

    INERTIA WATER SEPARATOR FOOD PACKAGING
    4.
    发明申请

    公开(公告)号:WO2023092017A1

    公开(公告)日:2023-05-25

    申请号:PCT/US2022/080061

    申请日:2022-11-17

    申请人: SAVR PAK INC.

    发明人: BIRGEN, William

    IPC分类号: B65D81/26 B65D51/16 B65D1/34

    摘要: This invention removes air moisture from inside a hot food container by first straightening the convection air flow rising above hot food, and second redirecting the rising air at a sharp turn, forcing the momentum of the heavier water-laden air to continue a straight trajectory into an absorbent pad or similar material, where the water from the air collides with the absorbent surface and is trapped. In this way, the invention extracts water from the air, before it can condense on food, thereby preventing the food to from becoming soggy. The invention is embodied in a food storage comprising four principal elements: (a) a housing for enclosing hot food, (b) a plurality of parallel passageways mounted inside the housing, (c) an absorbent layer positioned above the plurality of parallel passageways, and (d) a gap between the plurality of parallel passageways and the absorbent layer.

    REACTOR VENT CONTROL TO AVOID VENT COLUMN BREAKTHROUGH

    公开(公告)号:WO2023091854A1

    公开(公告)日:2023-05-25

    申请号:PCT/US2022/078960

    申请日:2022-10-31

    IPC分类号: B01D53/00 B01J8/00 B01D53/14

    摘要: Processes for venting gas phase olefin polymerization systems are provided. A portion of the reactor overhead can be withdrawn from the reactor to a vent column and contacted with a liquid stripping medium (L) within the vent column to remove at least a portion of the olefin monomer to produce a vent column overhead (G) and a vent column bottoms; recycling the vent column bottoms (rich in the olefin monomer and lean in the carrier gas) to the reactor; determining a L*N to C*G ratio, wherein L is total liquid stripping medium flow to the vent column, N is carrier gas concentration in the reactor overhead, C is the monomer concentration in the reactor overhead, and G is the vent column overhead gas flow. One or more of these flow streams (L, N, C, G) can then be controlled based on the calculated L*N to C*G ratio.

    SYSTEMS AND METHODS FOR RECYCLING WET WASTE MATERIALS

    公开(公告)号:WO2023091711A1

    公开(公告)日:2023-05-25

    申请号:PCT/US2022/050471

    申请日:2022-11-18

    摘要: Systems and methods for recycling wet wipe, or wet plastic comprising, products are provided. The recycling process can include processing broken-down wet waste material into a molten polymer using a dewatering, degassing, and compacting extruder. The recycling process can also include dewatering, degassing, and compacting the broken-down wet waste material and the molten polymer being processed in the dewatering, degassing, and compacting extruder and removing gas and waste material residue from the dewatering, degassing, and compacting extruder and capturing large residue particles.