US08466771B2
Disclosed is a sintered metal oxide used for thermistors, which includes a complex oxide represented by the following general formula: La1-yAy(Cr1-xMnx)O3 (with the proviso that A represents at least either one of Ca or Sr, and x and y satisfy 0.0≦x≦1.0 and 0.0
US08466760B2
Systems and methods for forming a configurable power supply uses a plurality of dual substrate MEMS switches to couple a plurality of power cells to provide a selectable, or variable, output voltage. The same circuit may output two different voltages to power two different circuits of the device, or may distribute the load evenly amongst the cells. Thus, the configurable power supply may extend the lifetime and improve the reliability of the device, or decrease its weight, size and cost.
US08466759B2
A reversible unit (10) is attached by being mounted over a pair of adjacently disposed electromagnetic contactors (1a) and (1b). The reversible unit (10) includes a pair of interlock plates (11) and (12), a lock piece (13), and a unit case (10b) accommodating the pair of interlock plates (11) and (12) and the lock piece (13). The lock piece (13) rotates in a first direction with the movement of one of the interlock plates (12) in a turn-on operation of one of the electromagnetic contactors (1a) to prevent the movement of the other interlock plate (11), and rotates in a second direction different from the first direction with the movement of the other interlock plate (11) in a turn-on operation of the other electromagnetic contactor (1b) to prevent the movement of one of the interlock plates (12). The unit case (10b) is provided with a lock piece display window (10g) which allows determination of the rotation of the lock piece (13) in the first direction or the second direction.
US08466757B2
A multilayer common mode filter is provided, which can inhibit cracks from occurring, while securing the magnetic coupling between coil conductors. Since magnetic layers are disposed in an inner region of spiral first and second coil conductors, the multilayer common mode filter can secure the magnetic coupling between the first and second coil conductors. In a columnar part including these magnetic layers, magnetic and nonmagnetic bodies are arranged alternately in the laminating direction, whereby the total volume of the magnetic layers in the inner region can be kept smaller than in the case where a magnetic layer penetrates through the inner region of the coil conductors. As a result, at the time of firing a matrix, the difference in the amount of shrinkage between the nonmagnetic and magnetic layers can be suppressed, so as to inhibit cracks from occurring at their interfaces.
US08466753B2
A metal base having plural protrusions at its bottom is engaged with and placed on standing metal pins in plural through holes provided in a base board, and a circuit board is fitted to an upper end of the metal pins. A crystal resonator is arranged on the circuit board via a heater element, and the metal base is covered with a metal cover, thereby obtaining a sealed structure of the crystal resonator. A two-stage counterbored portion including a first-stage and a second-stage counterbored portions is formed in the bottom of the base board, and a solder or conductive resin is filled in a gap between the first-stage counterbored portion formed around the metal pin inserted into the through hole, and the through hole and the metal pin to fix the metal pin in the though hole. Slits penetrating through the base board are formed around the metal pin.
US08466736B1
A circuit includes an amplifier having an input and an output; and at least one transistor comprising at least one terminal and at least one isolated well. The input of the amplifier is electrically connected to the at least one terminal of the transistor; and the output of the amplifier is electrically connected to the at least one isolated well of the at least one transistor.
US08466732B2
An input of a first inverter is configured to serve as an input node. An output of the first inverter is coupled to an input of a second inverter. An output of the second inverter is configured to serve as an output node. An input of a third inverter is coupled to an input of the first inverter. A gate of a first NMOS transistor is coupled to an output of the third inverter. A drain of the first NMOS transistor is coupled to the second inverter. A source of the first NMOS transistor is configured to serve as a level input node. When the input node is configured to receive a low logic level, the output node is configured to receive a voltage level provided by a voltage level at the level input node.
US08466726B2
Duty cycle correction systems and methods of adjusting duty cycles are provided. One such duty cycle correction system includes a duty cycle adjustor and a variable delay line coupled to the duty cycle adjustor. First and second phase detectors have first inputs coupled to the duty cycle adjustor through an inverter and second inputs coupled to the variable delay line. The phase detectors cause the delay line to align rising or falling edges of signals at the output of the delay line with rising or falling edges, respectively, of signals at the output of the inverter. The controller simultaneously causes the duty cycle adjustor to adjust the duty cycle of the output clock signal until the rising and falling edges of signals at the output of the delay line are aligned with rising and falling edges, respectively, of signals at the output of the inverter.
US08466724B2
Provided is a frequency synthesizer capable of fine setting over a wide band and having a wide frequency pull-in range. A sine wave signal of an output frequency of a voltage controlled oscillating part is quadrature-detected, and in a PLL utilizing a vector rotating at a frequency (velocity) equal to a difference from a frequency of a frequency signal used for the detection, a frequency pull-in means integrates a first constant for increasing the output frequency as a pull-in voltage when a control voltage from the PLL to the voltage controlled oscillating part is larger than a prescribed set range, and integrates a second constant for decreasing the output frequency as the pull-in voltage when the control voltage is smaller than the set range. Then, an adding means adds the control voltage from the PLL and the pull-in voltage from the frequency pull-in means to output an addition result to the voltage controlled oscillating part.
US08466717B2
The provision of a technique capable of determining a state where PLL control does not operate normally instantly or in advance in a frequency synthesizer that frequency-divides, A/D converts, and quadranture-detects a frequency signal from a voltage controlled oscillating unit, and extracts a rotation vector rotating at a frequency difference between the frequency signal used for the detection and the A/D converted frequency signal, and integrates a difference between a frequency of the above rotation vector and a set frequency to set an integration result as a control voltage to the voltage controlled oscillating unit. The control voltage to be input to the voltage controlled oscillating unit is monitored, and it is determined whether or not a level of the monitored control voltage deviates from a set range determined in advance, and an unlock detection signal is output. In a structure in which the rotation vector is multiplied by a reverse rotation vector reversely rotating at a frequency determined in rough increments according to the set frequency to reduce a velocity of the rotation vector, a determination result whether or not a length of the rotation vector whose velocity is reduced (a scalar quantity) or a correction signal for gain control deviates from a range set in advance is further considered.
US08466716B2
A synthesizer including an oscillator for outputting an oscillation signal based on an output signal from a comparator, a frequency divider for dividing a frequency of an output signal from the oscillator based on control from a controller, and a temperature sensor for detecting an error between a preset frequency and a frequency based on a reference oscillation signal. The comparator compares an output signal from the frequency divider with an output signal from a MEMS oscillator and outputs a signal indicating the comparison result to the oscillator. The controller changes the frequency division ratio of the frequency divider based on an output signal from the temperature sensor and changes the frequency division ratio in a state in which the frequency division ratio is kept at the past value. Thus, phase noise deterioration in the synthesizer can be suppressed.
US08466711B2
In one embodiment, a programmable priority encoder is configured to receive inputs, including an ordered list of a plurality of input request values each representing either a request or a non-request, and a starting position within the ordered list of the plurality of input request values. The programmable priority encoder is configured to generate an identification of a result position of a first input indicating said request in order from a position identified from the starting position within the ordered list. In one embodiment, the programmable priority encoder includes a hierarchal structure of logic blocks including a plurality of columns of logic blocks; wherein a first-stage column of the plurality of columns of logic blocks is configured to operate on at most N input values; and wherein the ordered list of the plurality of input request values consists of N input request values.
US08466707B2
In a particular embodiment, a method includes receiving a testing activation signal at a controller coupled to a semiconductor device. The method further includes biasing a well of at least one transistor of the semiconductor device in response to the received testing activation signal. The bias is provided by a biasing circuit that is responsive to the controller. While the well is biased, a test of the semiconductor device is performed to generate testing data.
US08466706B2
A combiner that calculates energy produced by each panel feed during the daytime, and calculates a resistance value needed to calculate the energy by injecting a known current into each panel feed at nighttime and measuring the resulting voltage across a resistive element in each panel feed. A voltage tap across the protection device in each panel feed allows logic and control circuitry to measure the voltage across each protection device. At nighttime, a known current is injected into each panel feed and the voltage across each protection device is measured. Plugging the current and voltage into Ohm's Law, a resistance of each protection device is calculated, then that resistance value is used during the daytime to calculate energy produced by each string in real time and to monitor each string's performance. When an individual string's performance wanes, an alarm is indicated to help the operator troubleshoot which individual panel(s) within the string is responsible for that string's underperformance.
US08466705B1
A system for analyzing electronic devices includes a first cab, an input station, a transport apparatus, an electric machine interface station, and an electric machine interface. The first cab includes a holder having formations for removably receiving a first subset of electronic devices and a communications interface. The input station receives the first cab and the transport apparatus transports the first cab with the first subset of electronic devices from the input station to the electric machine interface station. The electric machine interface is positioned to engage communicatively with the communications interface of the first cab when the first cab is at the electric machine interface station, and is disengageable from the communications interface of the first cab for the first cab to be transportable by the transport apparatus away from the electric machine interface station. Heat conducts to or from the electronic devices while they are being analyzed.
US08466698B2
A current sensor, which senses current passing through a harness via a terminal of a battery, includes a resistor through which current passes, a current sensing circuit which measures the current passing through the resistor based on a potential difference between two positions along the direction in which current is passed through the resistor, a power supply circuit which supplies power to the current sensing circuit, and at least one capacitor which is connected to at least one of an input terminal and an output terminal of the power supply circuit to smooth input/output voltage. The resistor includes a flat energizing path, and the capacitor is disposed in an area other than a plane of projection of the energizing path on a board on which the current sensing circuit and the power supply circuit are mounted.
US08466695B2
Systems and methods for real time detection of corrosion of rebars embedded in a concrete structure. Test bars are selected for corrosion testing purposes, and may or may not also be part of the concrete reinforcement structure. These test bars are coated, and exposed sections of these test bars form a network of node electrodes. Electrical measurement from a counter electrode near a node electrode provides an indication of corrosion at that node electrode. Using a system of node electrodes and counter electrodes, a large concrete area may be monitored, and if corrosion is indicated, a methodical selection of electrodes can be used to locate the corrosion. The same concepts may be applied to detect corrosion in buried structures, such as pipelines and tanks.
US08466693B2
A fill level measuring device for capacitive fill level measurement and/or travel time fill level measurement of a fill substance in a container. The measuring device has a coaxial measuring probe, whose inner conductor is galvanically isolated from its shield conductor, and whose shield conductor lies electrically at a reference potential. The device additionally includes: a securement apparatus lying electrically at a reference potential and serving for securement of the measuring device on a container opening equipped with a counterpart of the securement apparatus; and a washer made of an electrically conductive material and clamped in measurement operation between the securement apparatus and the counterpart. The inner conductor is completely surrounded in measurement operation by an insulating layer and passes through the washer into the container. The device additionally includes an insulating body adjoining the insulating layer and coaxially surrounding the inner conductor. The insulating body has a washer-shaped section clamped between the securement apparatus and the washer. The shield conductor coaxially surrounds the inner conductor and is connected mechanically and in an electrically conducting manner with the washer. At least one electrical contact element is affixed in the washer outside of a region of such covered by the insulating body and on a spring element. Via the contact element and the washer, the shield conductor is connected in an electrically conducting manner to the securement apparatus.
US08466690B2
A sensor for condition monitoring the high voltage insulation of an electrical, generation, transmission or distribution system and/or an item of plant is described. The sensor comprises an impedance measurement unit that connects directly, via a single point of connection, to the electrical system to be tested. The electrical components of the impedance measurement unit are arranged so that high frequency partial discharge signals and low frequency power cycle information signal are preferentially transmitted through separate branches. Analysis of these separated signals thus enables extraction of information about the insulation of the electrical system being monitored. Safe operation of the sensor for users is also achieved through an opto-electronic circuit being employed to control the impedance measuring unit.
US08466689B2
A method of monitoring a capacitor bank comprising a plurality of capacitor strings connected in parallel, each capacitor string comprising a plurality of capacitors connected in series is provided. The method includes energizing the capacitor bank. The method includes determining dissipation factors of each of the plurality of the capacitor strings. The method further includes comparing each of the determined dissipation factors with an expected dissipation factor and estimating a health state of the plurality of the capacitor strings based, at least in part, on the comparison of the determined and expected dissipation factors.
US08466684B2
A battery control module for use with a battery includes a voltage measuring module that measures battery voltage and a current measuring module that measures battery current. A power limit module communicates with the current and voltage measuring modules and once every time period estimates a battery current limit that corresponds with a future time period. The battery current limit is based on a predetermined voltage limit of the battery and a battery current and a battery voltage that correspond with a time period that precedes the future time period.
US08466680B2
A magnetic field generator includes a power source and a segmented or un-segmented coil connected to the power source to generate a time-varying magnetic field. Energy is applied to the coil so that the coil generates a time-varying magnetic field gradient with a magnitude of at least 1 milliTesla per meter and a rise-time of less than 10 microseconds. The coil may be comprised of overlapping, non-overlapping or partially overlapping coil segments that may individually energized to further improve the operating characteristics of the coil to further decrease bio-effects in magnetic resonance imaging through the use of reduced pulse lengths and multi-phasic magnetic gradient pulses.
US08466675B2
A magneto-impedance element with a longitudinal columnar section whose cross section about a longitudinal center axis is either a circle or a polygon inscribed in the circle, and which has a trap region configured to trap a magnetic substance that is formed in a band region extending along at least one of two lines of intersection between a plane containing the center axis and a lateral surface of the longitudinal columnar section and a non-trap region for a magnetic substance that is a region of the lateral surface of the magneto- impedance element excluding the trap region. The magneto-impedance element is used to provide a detection apparatus and a detection method that can easily detect a magnetic substance with high precision.
US08466670B1
A power supply for a gated load includes a power current source controlled by a current magnitude signal. A capacitor integrates the power current to produce load voltage. The power current is sampled, and compared with a reference voltage appearing across a reference capacitor, to produce the current magnitude signal. The reference voltage is controlled by a window comparator which charges the reference capacitor when the load voltage exceeds an upper threshold, and discharges the reference capacitor when the load voltage is less than a lower threshold. The window comparator is enabled by the load gating signal.
US08466667B2
A switch-mode power circuit comprises a controllable element and a control unit. The controllable element is configured to control a current in response to a control signal supplied to the controllable element. The control unit is connected to the controllable element and provides the control signal. The control unit comprises a first signal processing unit, a second signal processing unit, and a combiner unit. The first signal processing unit has an output and is supplied with a first carrier signal and an input signal. The second signal processing unit has an output and is supplied with a second carrier signal and the input signal. The combiner unit is connected to the first and second signal processing units combining the outputs of the first and the second signal processing units to form a signal representative of the control signal.
US08466659B2
An apparatus and method for rendering a battery safe for disposal by completing a circuit between positive and negative terminals to rapidly deplete the battery of power.
US08466657B2
A charge balancing circuit implemented within a charge storage device (cell) in a series connected charge storage unit (battery) made up of a plurality of cells. The charge balancing circuit may utilize a controller to sense the voltage in the cell it is implemented therein and the cells adjacent thereto. If the voltage of the current cell exceeds a threshold voltage and is greater than at least one adjacent cell the current cell can transfer charge to the adjacent cell having the lowest voltage. The transfer of the charge is done with a switching network that extracts current from the current cell and then transfers the current to the adjacent cell having the lowest voltage. The switching network may utilize switches and a current storage device (inductor) to transfer the charge. The controller may activate different switches based on which adjacent cell has the lowest voltage.
US08466653B2
In a battery charger, the rectifier includes rectifying elements provided for respective three phases. The rectifier supplies, for the respective phases, currents for rectifying three-phase AC voltages so as to charge a battery. A voltage detector detects whether or not the battery is charged. Switching units are provided for the respective rectifying elements, and rectify the AC voltages to charge the battery in the off-state. Switch controllers output gate signals in accordance with a timing of zero-cross detection upon receiving a detection signal indicating that all the gate signals for turning on and off the respective switching units for the respective phases are supplied in the order of the phases. On the other hand, upon receiving a detection signal indicating that all the gate signals for the respective phases are not supplied in the order of the phases, the switch controllers output gate signals to the corresponding switching units in synchronization with the detection signal so as to enter the shorting state.
US08466636B2
An excavator drive system wherein one of a pair of propulsion motors shares one of a pair of inverter power sources with another of a pair of motors dedicated to crowd and hoist motions. A pair of non-volatile bi-state switches, triggered under control of a controller, allow sharing of inverters between hoist and propel 1 motors. Another pair of switches allows inverter sharing between propel 2 and crowd motors. Each pair of switches enables change over and power transfer from one of the paired motors to the other motor. The bi-state switches enable quicker transfer of power between motors than transfer switches employing external motor-powered mechanical transfer linkages. Bi-state transfer switches also maintain transfer coupling status in the event of power failure to the switch actuators, allowing an excavator operator to continue the drive function in operation prior to the switch power failure.
US08466633B2
An illumination controlling device for a vehicle includes a controlling portion to change a luminance phase of a meter based on operation of an operating portion and to maintain a luminance phase of a lighting while the lighting is extinguished. The controlling portion changes the luminance phase of the meter based on the operation of the operating portion and changes the luminance phase of the lighting to correspond to the luminance phase of the meter if the operating portion is operated in a state that the luminance phase is different between the meter and the lighting while the lighting is illuminated.
US08466619B2
An illumination apparatus includes an adapter that converts power into driving power; a light emitting device illumination part that is detachably and electrically connected to the adapter to emit light according to the driving power from the adapter; and a driving unit that controls an illumination direction of the light emitting device.
US08466614B2
A front light plate includes a transparent substrate, a first electrode layer disposed on the transparent substrate and including first electrodes arranged in parallel, a second electrode layer disposed opposite to the first electrode layer and including second electrodes arranged in parallel, and light emitting components. The light emitting components arranged in array are disposed between the first electrode layer and the second electrode layer and at overlapping positions of the first electrodes and the second electrodes. Each of the light emitting components has a top surface connected to the corresponding first electrode, a bottom surface connected to the corresponding second electrode and a side surface between the top surface and the bottom surface. The side surface is a light emitting surface. The front light plate has high brightness uniformity and high light utility efficiency.
US08466609B2
An electrodeless or induction ceramic HID lamp includes a ceramic arc body having a generally spheroidal portion enclosing a discharge chamber and an induction coil received around a perimeter portion of the spheroidal portion. At least one leg extends from the spheroidal portion of the arc body. A mounting structure connects the arc body to the surrounding lamp assembly. In one arrangement, a mounting tube is received over at least a portion of the leg, and may further include a light transmissive shroud that also abuts with the induction coil to precisely locate the arc body relative to the coil. In another arrangement, first and second mounting members extend from spaced locations of the arc body, either as pins or legs extending from the spheroidal portion, or radially extending legs from an equatorial portion of the arc body. In still another arrangement, a ceramic mounting member extends from the arc body and includes a thin peripheral rim having spaced ridges to engage spaced locations of the induction coil.
US08466603B2
A driving apparatus is capable of efficiently transmitting a reciprocating displacement of an electromechanical transducer element to a movement member and of effectively utilizing a vacant space. The driving apparatus includes an electromechanical transducer element having first and second end faces opposed to each other in a direction of expansion and contraction thereof, a vibration friction portion attached to the second end face of the electromechanical transducer element, and a movement member friction-bonded to the vibration friction portion. The movement member is movable along the direction of expansion and contraction of the electromechanical transducer element. The driving apparatus includes a vibration transmission member arranged between the second end face of the electromechanical transducer element and an end face of the vibration friction portion. A central axis of the electromechanical transducer element and a central axis of the vibration friction portion are not on the same line.
US08466599B2
In an electrostatic micromotor, a mobile substrate faces a fixed substrate and is suspended over the fixed substrate at a given distance of separation in an operative resting condition; an actuation unit is configured so as to give rise to a relative movement of the mobile substrate with respect to the fixed substrate in a direction of movement during an operative condition of actuation. The actuation unit is also configured so as to bring the mobile substrate and the fixed substrate substantially into contact and to keep them in contact during the operative condition of actuation. The electrostatic micromotor is provided with an electronic unit for reducing friction, configured so as to reduce a friction generated by the contact between the rotor substrate and the stator substrate during the relative movement.
US08466598B2
An electric rotating machine includes a multi-phase stator coil that is wound on a stator core in a distributed winding manner. Each of phase windings of the stator coil is formed of an electric wire bundle which includes a plurality of insulation-coated electric wires that are electrically connected to one another. Each of the electric wire bundles forming the phase windings has in-slot portions, which are respectively received in corresponding slots of the stator core, and turn portions that are located outside the slots of the stator core to connect adjacent pairs of the in-slot portions. Each of the electric wire bundles further includes a plurality of insulating layers that are respectively formed at predetermined positions, at which the turn portions of the electric wire bundle overlap those of the other electric wire bundles, so as to surround the electric wires of the electric wire bundle.
US08466595B2
A hydroelectric turbine having a stator and a rotor housed concentrically within the stator, the turbine having a circumferentially disposed array of magnets on a rim of the rotor, and wherein the stator is slotless in configuration and is formed from a wire winding as opposed to the conventional toothed laminations, the turbine further having an annular array of individual coils mounted on the stator concentrically inwardly of the wire winding, each coil being provided with a dedicated rectifier to convert AC current induced in the coil into DC, preferably for transmission to a remote location.
US08466593B2
A method for fabricating a rotor assembly for an induction motor includes assembling a shorting end ring onto the rotor assembly which includes a steel laminate stack and a plurality of conductor bars. The shorting end ring includes a plurality of grooves aligned with corresponding portions of the conductor bars extending from a first end of the steel laminate stack. Assembling includes inserting the corresponding portions of the conductor bars into the grooves of the shorting end ring. The shorting end ring is affixed to the rotor assembly by applying a compressive force around a perimeter of the shorting end ring to deform the conductor bars.
US08466582B2
A method and apparatus for applying an electric field to a photovoltaic element. In one embodiment, the apparatus comprises at least one photovoltaic (PV) cell having a P-N junction; and a voltage supply for (i) converting a first voltage to an e-field voltage, the first voltage generated local to the at least one PV cell, and (ii) coupling the e-field voltage to the at least one PV cell to create an electric field extending across the P-N junction.
US08466573B2
A wind turbine generator system can regulate the rotational velocity of the wind turbine within an operation range even when the wind velocity suddenly changes and can perform continuous operation of the wind turbine. The wind turbine generator system includes a generator connected to the shaft of the wind turbine and a converter connected to the generator. When the rotational velocity of the wind turbine is within a predetermined range, power outputted from the generator is controlled so as to follow the instruction concerning the generator output given from the wind turbine to the converter. When the rotational velocity of the wind turbine is out of the predetermined range, the power outputted from the generator is controlled without following the instruction concerning generator output given from the wind turbine to the converter.
US08466569B2
An improved alignment structure for photolithographic pattern alignment is disclosed. A topographical alignment mark in an IC under a low reflectivity layer may be difficult to register. A reflective layer is formed on top of the low reflectivity layer so that the topography of the alignment mark is replicated in the reflective layer, enabling registration of the alignment mark using common photolithographic scanners and steppers. The reflective layer may be one or more layers, and may be metallic, dielectric or both. The reflective layer may be global over the entire IC or may be local to the alignment mark area. The reflective layer may be removed during subsequent processing, possibly with assist from an added etch stop layer, or may remain in the completed IC. The disclosed alignment mark structure is applicable to an IC with a stack of ferroelectric capacitor materials.
US08466561B2
A semiconductor module includes a power semiconductor chip and a passive discrete component. The semiconductor chip includes on its top side and/or on the back side a large-area contact, which in its two-dimensional extent takes up the top side and/or the back side of the semiconductor chip virtually completely. The passive component, arranged in a package, is stacked on one of the large-area contacts. The electrode of the passive component is electrically connected with one of the large-area contacts. The counter electrode of the passive component is operatively connected with a control or signal electrode of the power semiconductor chip or an electrode of a further semiconductor chip.
US08466549B2
A semiconductor device formed by using semiconductor packages is provided. The semiconductor device includes two semiconductor packages adjacently arranged in opposite directions on an inductive conductor. Terminals of the two semiconductor packages are joined by a third lead. The third lead is arranged substantially in parallel to the inductive conductor. Leads at the joint portions have, for example, a bent structure, and the third lead is arranged to be close to the inductive conductor.
US08466547B2
Provided is a manufacturing method of a substrate for a semiconductor element including the steps of: providing a first photosensitive resin layer on a first surface of a metal plate; providing a second photosensitive resin layer on a second surface different from the first surface of the metal plate; forming a first etching mask for forming a connection post on the first surface of the metal plate; forming a second etching mask for forming a wiring pattern on the second surface of the metal plate; forming the connection post by performing an etching from the first surface to a midway of the metal plate; filling in a premold resin to a portion of the first surface where the connection post does not exist; processing so that a height of the connection post of the first surface is lower than a height of the premold resin surrounding the connection post; and forming the wiring pattern by performing an etching on the second surface.
US08466543B2
An apparatus, system, and method are disclosed for connecting integrated circuit devices. A plurality of primary electrically conductive contacts and a plurality of primary electrically conductive pillars are electrically coupled to a primary integrated circuit device. The plurality of primary electrically conductive contacts form a pattern corresponding to secondary electrically conductive contacts disposed on one or more secondary integrated circuit devices. The plurality of primary electrically conductive pillars extends away from the primary integrated circuit device. The plurality of primary electrically conductive pillars forms a pattern that corresponds to substrate electrically conductive contacts that are disposed on a substrate. The plurality of primary electrically conductive pillars and associated connecting material provide a standoff height between the primary integrated circuit device and the substrate that is greater than or equal to a height of the one or more secondary integrated circuit devices.
US08466542B2
A stacked microelectronic assembly is provided which includes first and second stacked microelectronic elements. Each of the first and second microelectronic elements can include a conductive layer extending along a face of such microelectronic element. At least one of the first and second microelectronic elements can include a recess extending from the rear surface towards the front surface, and a conductive via extending from the recess through the bond pad and electrically connected to the bond pad, with a conductive layer connected to the via and extending along a rear face of the microelectronic element towards an edge of the microelectronic element. A plurality of leads can extend from the conductive layers of the first and second microelectronic elements and a plurality of terminals of the assembly can be electrically connected with the leads.
US08466538B2
The present invention is an SOI wafer comprising at least: an SOI layer; a silicon oxide film; and a base wafer, wherein the SOI layer has a plane orientation of (100), and the base wafer has a resistivity of 100 Ω·cm or more and a plane orientation different from (100). As a result, there is provided the SOI wafer and the manufacturing method thereof that have no complicated manufacturing step, defects on a bonding interface which are not practically a problem in number and a high interface state density (Dit) for trapping carriers on an interface of a BOX layer and the base wafer.
US08466530B2
A system and method for image sensing is disclosed. An embodiment comprises a substrate with a pixel region, the substrate having a front side and a backside. A co-implant process is performed along the backside of the substrate opposing a photosensitive element positioned along the front side of the substrate. The co-implant process utilizes a first pre-amorphization implant process that creates a pre-amorphization region. A dopant is then implanted wherein the pre-amorphization region retards or reduces the diffusion or tailing of the dopants into the photosensitive region. An anti-reflective layer, a color filter, and a microlens may also be formed over the co-implant region.
US08466529B2
According to one embodiment, an imaging device includes a substrate, a photodetecting portion, a circuit portion and a through interconnect. The substrate has a first major surface, a second major surface on a side opposite to the first major surface, a recess portion provided on the first major surface and retreated in a first direction going from the first major surface to the second major surface, and a through hole communicating with the first major surface and the second major surface and extending in the first direction. The photodetecting portion is provided above the recess portion and away from the substrate. The circuit portion is electrically connected to the photodetecting portion and provided on the first major surface. The through interconnect is electrically connected to the circuit portion and provided inside the through hole. The recess portion has a first inclined surface. The through hole has a second inclined surface.
US08466526B2
A Hall sensor has a P-type semiconductor substrate and a Hall sensing portion having a square shape and an N-type conductivity disposed on a surface of the semiconductor substrate. The Hall sensor includes Hall voltage output terminals having the same shape with each other, and control current input terminals having the same shape with each other. The Hall voltage output terminals are disposed at respective ones of four vertices of the Hall sensing portion. The control current input terminals include pairs of control current input terminals disposed at respective ones of the four vertices of the Hall sensing portion and arranged on both sides of respective ones of the Hall voltage output terminals in spaced apart relation from the Hall voltage output terminals so as to prevent electrical connection between the control current input terminals and the Hall voltage output terminals.
US08466524B2
Apparatus and associated method for writing data to a non-volatile memory cell, such as spin-torque transfer random access memory (STRAM). In accordance with some embodiments, a resistive sense element (RSE) has a heat assist region, magnetic tunneling junction (MTJ), and pinned region. When a first logical state is written to the MTJ with a spin polarized current, the pinned and heat assist regions each have a substantially zero net magnetic moment. When a second logical state is written to the MTJ with a static magnetic field, the pinned region has a substantially zero net magnetic moment and the heat assist region has a non-zero net magnetic moment.
US08466521B2
A hydrogen ion-sensitive field effect transistor and a manufacturing method thereof are provided. The hydrogen ion-sensitive field effect transistor includes a semiconductor substrate, an insulating layer, a transistor gate, and a sensing film. A gate area is defined on the semiconductor substrate having a source area and a drain area. The insulating layer is formed within the gate area on the semiconductor substrate. The transistor gate is deposited within the gate area and includes a first gate layer. Further, the first gate layer is an aluminum layer, and a sensing window is defined thereon. The sensing film is an alumina film formed within the sensing window by oxidizing the first gate layer. Thus, the sensing film is formed without any film deposition process, and consequently the manufacturing method is simplified.
US08466517B2
A method of forming capacitorless DRAM over localized silicon-on-insulator comprises the following steps: A silicon substrate is provided, and an array of silicon studs is defined within the silicon substrate. An insulator layer is defined atop at least a portion of the silicon substrate, and between the silicon studs. A silicon-over-insulator layer is defined surrounding the silicon studs atop the insulator layer, and a capacitorless DRAM is formed within and above the silicon-over-insulator layer.
US08466516B2
According to one embodiment, a semiconductor device includes a semiconductor substrate of a first conductivity type, an element isolation insulator, a source layer of a second conductivity type, a drain layer of the second conductivity type, a contact layer of the first conductivity type and a gate electrode. The element isolation insulator is formed on the semiconductor substrate. The source layer is formed on the semiconductor substrate and is in contact with a side surface of the element isolation insulator. The drain layer is formed on the semiconductor substrate, is in contact with the side surface, and is spaced from the source layer. The contact layer is formed between the source layer and the drain layer. The gate electrode is provided on the element isolation insulator along the side surface.
US08466512B2
A method for producing a semiconductor device includes preparing a structure having a substrate, a planar semiconductor layer and a columnar semiconductor layer, forming a second drain/source region in the upper part of the columnar semiconductor layer, forming a contact stopper film and a contact interlayer film, and forming a contact layer on the second drain/source region. The step for forming the contact layer includes forming a pattern and etching the contact interlayer film to the contact stopper film using the pattern to form a contact hole for the contact layer and removing the contact stopper film remaining at the bottom of the contact hole by etching. The projection of the bottom surface of the contact hole onto the substrate is within the circumference of the projected profile of the contact stopper film formed on the top and side surface of the columnar semiconductor layer onto the substrate.
US08466508B2
A non-volatile memory structure including a substrate, stacked patterns and stress patterns is provided. The stacked patterns are disposed on the substrate. Each of the stacked patterns includes a charge storage structure and a gate from bottom to top. Here, the charge storage structure at least includes a charge storage layer. The stress patterns are disposed on the substrate between the two adjacent stacked patterns, respectively.
US08466504B2
A DRAM with dopant stop layer includes a substrate, a trench-type transistor and a capacitor electrically connected to the trench-type transistor. The trench-type transistor includes a gate structure embedded in the substrate. A source doping region and a drain doping region are disposed in the substrate at two sides of the gate structure. A boron doping region is disposed under the source doping region. A dopant stop layer is disposed within the boron doping region or below the boron doping region. The dopant stop layer includes a dopant selected from the group consisting of C, Si, Ge, Sn, Cl, F and Br.
US08466485B2
Disclosed is a semiconductor light emitting device. The semiconductor light emitting device comprises a first conductive semiconductor layer, an active layer under the first conductive semiconductor layer, a second conductive semiconductor layer under the active layer, a second electrode layer under the second conductive semiconductor layer, and a transmissive conductive layer at least one part between the second conductive semiconductor layer and the second electrode layer.
US08466484B2
The present teachings provide methods for forming organic layers for an organic light-emitting device (OLED) using a thermal printing process. The method can further use one or more additional processes, such as vacuum thermal evaporation (VTE), to create an OLED stack. OLED stack structures are also provided wherein at least one of the charge injection or charge transport layers is formed by a thermal printing method at a high deposition rate. The organic layer can be subject to post-deposition treatment such as baking. The structure of the organic layer can be amorphous, crystalline, porous, dense, smooth, rough, or a combination thereof, depending on deposition parameters and post-treatment conditions. The organic layer can improve light out-coupling efficiency of an OLED, increase conductivity, decrease index of refraction, and/or modify the emission chromaticity of an OLED. An OLED microcavity is also provided and can be formed by one of more of these methods.
US08466482B2
A high performance electric device which uses an adhesive layer over a substrate. A color filter is over a substrate, and an adhesive layer is also located over the substrate and color film. An insulating layer is over the adhesive layer, and thin film transistors cover the insulating film and the color filters. Light emitting elements cover the thin film transistors and emit light through the substrate that is through the adhesive layer and color filter. The substrate may be plastic, thus increasing the heat resistance.
US08466481B2
A first intermediate electrode 30 is a plural number of electrodes connecting to plural electrode forming parts formed in plural places, respectively on the surface of a first semiconductor layer 104. A second intermediate electrode 40 is a plural number of electrodes connecting to plural places of a transparent electrically conductive film 10, respectively. A first electrode 60 connects a plural number of the first intermediate electrodes 30 to each other, and a second electrode 70 connects a plural number of the second intermediate electrodes 40 to each other. The transparent electrically conductive film 10 is formed thin in a region A where a distance between the first intermediate electrode and the second intermediate electrode is the shortest, as compared with other regions.
US08466480B2
A light emitting device according to the embodiment includes a conductive support substrate including plural pairs of first and second conductive layers; alight emitting structure layer including a first conductive semiconductor layer, a second conductive semiconductor layer, and an active layer between the first and second conductive semiconductor layers on the conductive support substrate; and an electrode on the light emitting structure layer. The first and second conductive layers are formed by using the same material.
US08466475B2
A light detecting chip includes at least one detection region configured to accommodate a sample that is capable of emitting fluorescent light, and a light reflecting section configured to reflect at least a portion of the fluorescent light emitted from the sample in a direction toward a light detector.
US08466473B2
A semiconductor device is provided that includes a semiconductor substrate having a well region located within an upper region thereof. A semiconductor material stack is located on the well region. The semiconductor material stack includes, from bottom to top, a semiconductor-containing buffer layer and a non-doped semiconductor-containing channel layer; the semiconductor-containing buffer layer of the semiconductor material stack is located directly on an upper surface of the well region. The structure also includes a gate material stack located directly on an upper surface of the non-doped semiconductor-containing channel layer. The gate material stack employed in the present disclosure includes, from bottom to top, a high k gate dielectric layer, a work function metal layer and a polysilicon layer.
US08466469B2
A pair of substrates forming the active matrix liquid crystal display are fabricated from resinous substrates having transparency and flexibility. A thin-film transistor has a semiconductor film formed on a resinous layer formed on one resinous substrate. The resinous layer is formed to prevent generation of oligomers on the surface of the resinous substrate during formation of the film and to planarize the surface of the resinous substrate.
US08466466B2
An organic light-emitting display device includes a first substrate having transmitting regions and pixel regions separated from each other by the transmitting regions, a plurality of thin film transistors on the first substrate in the pixel regions, a passivation layer covering the plurality of thin film transistors, a plurality of pixel electrodes on the passivation layer and electrically connected to the thin film transistors, the pixel electrodes being in the pixel regions and overlapping the thin film transistors, an opposite electrode in the transmitting regions and the pixel regions, the opposite electrode facing the plurality of pixel electrodes and being configured to transmit light, an organic emission layer interposed between the pixel electrodes and the opposite electrode, and a color filter in corresponding pixel regions.
US08466462B2
A thin film transistor (TFT) including a gate electrode, an active layer, and source and drain electrodes. The active layer includes contact regions that contact the source and drain electrodes, which are thinner than a remaining region of the active layer. The contact regions reduce the contact resistance between the active material layer and the source and drain electrodes.
US08466461B2
Example embodiments relate to a resistive random access memory (RRAM) and a method of manufacturing the RRAM. A RRAM according to example embodiments may include a lower electrode, which may be formed on a lower structure (e.g., substrate). A resistive layer may be formed on the lower electrode, wherein the resistive layer may include a transition metal dopant. An upper electrode may be formed on the resistive layer. Accordingly, the transition metal dopant may form a filament in the resistive layer that operates as a current path.
US08466460B2
A polymer comprising repeating units A and optionally repeating units B wherein Z=S, Se, N—R and O; W is at each occurrence independently a monocyclic or polycylic moiety optionally substituted with 1-4 Ra groups; Y, at each occurrence, is independently a divalent C1-6 alkyl group, a divalent C1-6 haloalkyl group, or a covalent bond; c is from 1 to 6.
US08466458B2
An organic light-emitting device including a mixed organic layer that includes a triphenyl amine derivative and a pyrazine derivative and an emission layer that includes an anthracene derivative, an amine-containing styryl derivative, or any mixture thereof.
US08466455B2
Organic light emitting devices are provided having multiple subpixels. An organic spacer layer is provided in at least one subpixel to protect the emissive layer of the at least one subpixel from overspray due to the deposition of a different emissive layer in a nearby subpixel. More generally, a first device is provided, where the first device comprises a multicolor organic light emitting device. The first device may be the multicolor organic device itself. Or, the first device may be a larger device, such as a consumer device, that includes one or many of the multicolor organic devices. The multicolor organic light emitting, device further comprises multiple subpixels. In the most general case, there are at least a first subpixel and a second subpixel.
US08466453B2
The invention relates to an organic electronic luminescent component with an arrangement of organic layers formed between an electrode and a counter electrode, wherein said arrangement of organic layers is electrically insulated from the electrode and the counter electrode and comprises a light-emitting layer and a charge carrier generation region allocated to the light-emitting layer, wherein the charge carrier generation region is configured to provide positive and negative charge carriers at an application of an electrical AC voltage to the electrode and the counter electrode and wherein a pn-layer transition is formed in the charge carrier generation region by means of a p-doped organic layer and a n-doped organic layer arranged next to the p-doped organic layer.
US08466452B2
A color unit is disclosed in which is included in an imaging device. The color unit includes; a first p-type electrode layer disposed on a light receiving side of the color unit, and including a light-absorptive organic material which selectively absorbs a wavelength other than a desired wavelength in a visible light band of the electromagnetic spectrum, a second p-type electrode layer disposed under the first p-type electrode layer and including a light-absorptive organic material which absorbs a desired wavelength and an n-type electrode layer disposed under the second p-type electrode layer and including an organic material, wherein photoelectric conversion is performed through a p-n junction between the second p-type electrode layer and the n-type electrode layer and light of the desired wavelength is converted into electrical current.
US08466445B2
The invention is related to methods and apparatus for providing a resistance variable memory element with improved data retention and switching characteristics. According to an embodiment of the invention a resistance variable memory element is provided having at least one silver-selenide layer in between glass layers, wherein at least one of the glass layers is a chalcogenide glass, preferably having a GexSe100-x composition.
US08466438B2
A system to selectively display a symbol at a location on a vehicle window. The system includes an arrangement of a fluorescent material at the location, wherein the fluorescent material: a) is sufficiently transparent in the absence of ultraviolet (UV) light, b) fluoresces when illuminated with UV light, c) and has a shape corresponding to the symbol, and a UV light source configured to illuminate the location with UV light to display the symbol. Such a system may use unfocused UV light sources to illuminate the symbol shaped fluorescent material as opposed to focused UV light sources such as UV lasers.
US08466437B2
A compact image sensor for imaging radiation emitted by fluorescing objects exposed to excitation light is disclosed. The compact image sensor includes a light guide defining a longitudinal axis for channeling radiation emitted by the fluorescing object; a reflective surface defined on the light guide that is oriented at an angle with respect to the longitudinal axis of the light guide to reflect the excitation light away from a detector of the image sensor; and the detector positioned at an end of the light guide for imaging radiation emitted by the fluorescing object. Also disclosed is a fluorescence imaging system for imaging radiation emitted by a fluorescing object to be imaged by compact image sensor and a method of fluorescence imaging.
US08466431B2
Techniques for improving extracted ion beam quality using high-transparency electrodes are disclosed. In one particular exemplary embodiment, the techniques may be realized as an apparatus for ion implantation. The apparatus may comprise an ion source for generating an ion beam, wherein the ion source comprises a faceplate with an aperture for the ion beam to travel therethrough. The apparatus may also comprise a set of extraction electrodes comprising at least a suppression electrode and a high-transparency ground electrode, wherein the set of extraction electrodes may extract the ion beam from the ion source via the faceplate, and wherein the high-transparency ground electrode may be configured to optimize gas conductance between the suppression electrode and the high-transparency ground electrode for improved extracted ion beam quality.
US08466424B2
A device that detects electromagnetic radiation, including an assembly of juxtaposed parallelepipedic semiconductor detection blocks, each detection block including a given length separating a detection face and at least one rear face opposite to the said detection face, a given thickness separating a first polarization face with one or more electrodes and a second polarization face with one or more other electrodes, and a given width.
US08466423B2
An X-ray radiation detector is disclosed for detecting ionizing radiation, in particular for use in a CT system, with a multiplicity of detector elements. In at least one embodiment, each detector element includes a semiconductor used as detector material with an upper side facing the radiation and a lower side facing away from the radiation, at least two electrodes, wherein one electrode is formed on the upper side of the semiconductor by a metallization layer, and the sum of all detector elements forms a base, which has a base normal at each point. In at least one embodiment, the invention is distinguished by the fact that the upper side of the semiconductor has a surface structure with a surface normal at each point, wherein the surface normal at least in part subtends an angle to the base normal. In at least one embodiment, the invention furthermore relates to a CT system provided with an X-ray radiation detector, which advantageously includes a multiplicity of detector elements structured according to at least one embodiment of the invention.
US08466422B2
Methods, camera, and a computer-readable medium for registering on a camera display infrared and visible light images of a target scene taken from different points of view causing a parallax error.
US08466415B2
Methods for using sub-100V electron beam landing energies for performing circuit edit operations. Circuit edit operations can include imaging for navigation and etching in the presence of a suitable gas. Low landing energies can be obtained by modifying a decelerator system of native FESEM equipment, or by using biasing means near the sample surface for decelerating electrons of the primary beam. At low landing energies near the operating voltage of a semiconductor circuit, voltage contrast effects can be visually seen for enhancing operator navigation. Low landing energies can be used during etching processes for minimizing the interaction volume of the beam and obtaining accurate and localized etching.
US08466407B2
Asymmetric rotating stray light baffles are provided for conformal dome two-axis seekers having arch corrector optics mounted on the outer gimbal. A pair of side skirt baffles are mounted on opposite sides of the arch corrector optics on the outer gimbal extending forward beyond the transparent arch adjacent but not touching the inner surface of the dome and extending aft beyond the forward most receiver optic for all fields of regard (FOR). The optical system may also include: (a) an annular objective baffle mounted on and around the receiver optics on the inner gimbal and between the pair of side skirt baffles, the objective baffle extending forward of the receiver optics without interfering with the receiver optics' FOV and without interfering with the transparent arch as the inner gimbal rotates, (b) a plurality of fin baffles mounted between the side skirt baffles on the outer gimbal that extend forward adjacent but not touching the inner surface of the dome and aft of the transparent arch, each fin baffle positioned to reduce the cross-section seen by the receiver optic when rotated in the direction of that fin baffle and (c) central baffles (short or long) along the axis of symmetry that obscure a portion of the receiver optics' FOV at a zero degree angle of rotation about the second axis.
US08466389B2
A method for producing superalloy weld wire and weld wire having fewer inclusions, and specifically fewer hafnia inclusions, and superalloy weld wire, particularly hafnium-containing superalloy weld wire, produced by this method. The method includes producing directionally solidified cast rod in a diameter of less than about ½ inch. The rod preferably is produced by investment casting or by continuous casting. The directional solidification process results in rod having inclusions such as oxides and dirt segregated into portions of the casting where they are easily removed. The cast rod can then be formed into semi-finished weld wire using a single extrusion step, followed by grinding to the final required diameter.
US08466388B2
A workpiece processing machine, such as a laser cutting machine, includes a motion unit having an associated drive, a cutting head mounted on the motion unit and configured to deliver a cutting beam, and a suction duct or other form of beam interceptor coupled to the motion unit so that it moves therewith and an opening of the suction duct is positioned below the cutting head during a workpiece processing operation. The machine also includes a frame configured to support the motion unit and defining a movement area of the motion unit, the frame having a beam located generally centrally in the movement area.
US08466381B2
A push button switch includes a hollowed housing, an electric switching circuit coupled to the hollowed housing and a stack of non-conductive sliders disposed within a narrow recess in the housing. An array of externally accessible push rods extends vertically through the housing and is used to longitudinally displace certain sliders into selective engagement with movable contacts in the electric switching circuit. A plurality of outwardly protruding projections are formed on at least one of the front and rear surfaces of alternating sliders, each projection being generally circular in transverse in cross-section and in the range of approximately 0.001 inches to 0.004 inches in height. The entire surface contact established between adjacent sliders is achieved through the one or more projections, thereby reducing the frictional forces experienced within the stack during slider displacement.
US08466378B1
A snap tight electrical connector for securing and grounding an electrical cable or conduit to a junction box. The electrical connector includes a one-piece, electrically conductive connector body with a seat on the leading end and an electrically conductive snap ring held in the seat. A raised grounding lug on the seat of the connector body extends through a notch in the snap ring and provides a direct path for establishing an electrical grounding path between the connector body and the junction box. Locking tangs on the snap ring provide a secure snap-fit engagement between the connector body and the junction box. The raised grounding lug on the seat of the connector body provides a direct grounding path between the connector body and the junction box, thereby improving electrical continuity and lowering the millivolt drop between the connector body, the junction box, and the electrical cable or conduit secured to the connector body.
US08466368B2
A high-frequency device according to one embodiment includes: a plate-like first dielectric substrate; a plurality of surface electrodes for capacitors which are formed on a surface of the first dielectric substrate; a rear face electrode for the capacitors which is formed on a rear face of the first dielectric substrate; a second dielectric substrate which is laminated on the first dielectric substrate and has an opening portion through which a plurality of the surface electrodes are exposed; a transmission line which is formed on a surface of the second dielectric substrate; and a conductive member to connect a plurality of the surface electrodes to the transmission line. The first dielectric substrate is made of dielectric material having a first dielectric constant. The second dielectric substrate is made of dielectric material having a second dielectric constant. The first dielectric constant is higher than the second dielectric constant.
US08466364B2
There is provided a cable fixing member, comprising: an intermediate member crimped and tightened to a cable; a pair of bracket members for clamping and grasping one or a plurality of cables with the intermediate member tightened thereto, through the intermediate member; and one or a plurality of grooves formed on facing surfaces of the pair of bracket members by which the cable is clamped, for clamping the cable through the intermediate member, wherein an inner surface shape of the groove is formed to mesh with an outer surface shape of the intermediate member which is crimped and tightened to the cable.
US08466342B2
Compositions and methods for regulating expression of heterologous nucleotide sequences in a plant are provided. Compositions include a novel nucleotide sequence for a maize early endosperm 5 (eep5) promoter. Also provided is a method for expressing a heterologous nucleotide sequence in a plant using a promoter sequence disclosed herein.
US08466340B2
The present invention provides mouse models for Pompe disease and methods of using the same to test agents that may be effective in the treatment of Pompe disease.
US08466332B1
A method and apparatus is provided for the continuous microwave depolymerization of high molecular weight organic feedstock material, such as waste plastics and includes intermittent or continuous feeding of the processing material on the surface or into the bulk of the sensitized hot bed located under microwave irradiation. As a result of the interaction of electromagnetic field with processed materials, sensitizer is heated by microwave energy and feedstock material undergoes the depolymerization reactions. The reaction zone can be localized on the surface of the hot bed or distributed in the bulk of the reaction mass depending on the agitation conditions of the reaction mass, such as stirring, or other agitation means, for example by recirculated gas. Products of the reactions are vaporized and transported to the collection system, which may include a combination of a scrubber, a condenser and a settler.
US08466331B2
A gasification apparatus is provided which enables gas hydrate pellets to be transported and gasified in the same vessel and enables a gas to be generated by pellet decomposition in a controlled amount. The apparatus is free from bridging. The apparatus includes a heat-in-saluted vessel main body and, disposed therein, a tubular structure which is open at the top and bottom. This tubular structure holds therein gas hydrate pellets obtained by compression-molding a gas hydrate produced by the hydration reaction of a raw-material gas with raw-material water. The tubular structure becomes wider in diameter from the upper opening toward the lower opening. A channel for passing a heat carrier therethrough has been disposed between the lower end of the tubular structure and the inner bottom surface of the vessel main body. The apparatus is further equipped, between the tubular structure and the inner wall surface of the vessel main body, with a nozzle which ejects the heat carrier in a circumferential direction for the vessel main body. The vessel main body has a discharge pipe for discharging the heat carrier ejected from the nozzle, the discharge pipe projecting upright from the inner bottom surface of the vessel main body.
US08466313B2
The present invention provides an improved method for fluoridation of an iodonium salt wherein a solution of the iodonium salt comprising a free radical trap is stored before the reaction is carried out. The method of the invention may be automated, which is particularly convenient when the method of the invention is radiofluoridation. As such the present invention also provides a cassette comprising the iodonium salt solution suitable for carrying out the method of the invention on an automated synthesizer.
US08466309B2
The disclosure relates to novel compounds of the formula (I) R1NH—CH(R2)CH2—S—S—CH2—C(R3)(R4)—CONH—C(R5)(R6)—COOR7, in which R1 is a (acyloxy)alkyl carbamate-C(O)—O—C(R8)(R9)—OC(O)—R10 group; R2 is a hydrocarbon chain, a methylene radical substituted by a heterocycle, R4 is a hydrogen atom and R3 is a phenyl or benzyl radical, a heteroaryl, a methylene group substituted by a heterocycle or R3 and R4 form together a saturated cycle; R5 and R6 are hydrogen, a hydrocarbon chain, a phenyl or benzyl radical or R5 and R6 form together a saturated cycle; R7 is hydrogen, a phenyl or benzyl radical, a group of the formula CR12(R13)C(O)OR14 or OCR12(R13)OC(O)R14 or OCR12(R13)OC(O)OR14. The disclosure also relates to the use of these compounds as a drug, and to a pharmaceutical composition containing said compounds and a pharmaceutically acceptable carrier. The disclosure further relates to the combined use of at least one cannabinoid derivative and/or morphine or one derivative thereof and/or Gaba derivatives for enhancing the analgesic and anti-depressive effect of the compounds of the formula (I).
US08466307B2
The present invention relates to the field of one step process for the preparation of monomeric or dimeric [Ru(diene)(OOCR)2]n complexes from [(diene)RuCl2]n, as well as a new class of [Ru(diene)(OOCR)2]n complexes and their use to prepare [Ru(PP)(OOCR)2] complexes, which are good catalysts.
US08466305B2
The present invention relates to systems and methods of using fatty acid alkyl ester solutions to refine feed stocks before converting the feed stocks into fatty acid fatty acid alkyl esters. In an embodiment, the invention includes a method for producing fatty acid alkyl esters. The method can include mixing a crude lipid feed stock with a refining solution to form a crude product mixture, the refining solution comprising greater than about 10 wt. % fatty acid alkyl esters. The method can include extracting the liquid phase from the crude product mixture to obtain a purified lipid feed stock. The method can also include reacting the purified lipid feed stock with an alcohol to form a product mixture comprising fatty acid alkyl esters. In an embodiment, the invention includes a method of making a fatty acid alkyl ester composition. The method can include extracting lipids from a corn-based ethanol production byproduct, adding an alcohol solution to the lipids to form a reaction mixture, and contacting the reaction mixture with a metal oxide catalyst. Other embodiments are included herein.
US08466298B2
Provided are a kind of high selectivity polymeric adsorbents with amide functional groups based on the hydrogen bonding interaction, which is prepared by adequately swelling a DVB-co-MA copolymer of 6% crosslinking degree as the initial resin with dimethyl formamide, performing an amination reaction by adding a diamine, soaking the dried resultant yellow resin with an acylating agent that is a dianhydride, and performing an acylation reaction to obtain the polymeric adsorbent with amide functional groups of the invention. The polymeric adsorbent of the invention can be used to effectively isolate and purify the active ingredients, i.e., flavones and lactones, from the extract of ginkgo leaf.
US08466297B2
The present invention relates to a novel manufacturing process and novel intermediates useful in the synthesis of pharmaceutically active compounds of general formula I used for treatment of epilepsy, neuropathic pain, anxiety and social phobia. The invention describes preparation of enantiomerically pure (S)-Pregabalin from chiral pyrrolidin-2-one of formula IV.
US08466295B2
The present invention provides compounds of Formula (I): or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein the variables A, L1, R3, and R11 are as defined herein. The compounds of Formula (I) are useful as selective inhibitors of serine protease enzymes of the coagulation cascade and/or contact activation system; for example thrombin, factor Xa, factor XIa, factor IXa, factor VIIa and/or plasma kallikrein. In particular, it relates to compounds that are selective factor XIa inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.
US08466282B2
Compounds represented by the formulas (I) (II) wherein each symbol is as defined in the specification, and a prodrug thereof have a superior renin inhibitory activity, and are useful as agents for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension and the like.
US08466269B2
A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate and has at least two amino acid substitutions relative to the wild-type hydrolase. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein.
US08466268B2
Lactobacillus sp. strain with antimutagenic activity and, more particularly, Lactobacillus sp. JNU2116 having a specific amino acid sequence at an N-terminal. Such strain has various advantages in that it has antimutagenic activity to inhibit mutation of cells thus preventing cancer caused by modification of genes, may be added to general fermented dairy products, food additives and/or health foods so as to be simply applied to the human body by the intake of food and, in addition, may be safely used without side effects from intake thereof. The strain was deposited with Accession No. KCCM11055P to Korea Culture Center of Microorganisms (KCCM) (having the address of 361-221, Yurim B/D. Hongje-1-dong, Seodaemun-gu, Seoul, 120-091, Republic of Korea) on Dec. 2, 2009.
US08466266B2
The present invention provides a new class of solids supports for synthesis of modified oligomers of nucleic acids, and nucleic acid probes that have a format expediently synthesized on the new supports. Exemplary solid supports include at least one quencher bound through a linker to the solid support. Various exemplary embodiments include a moiety that stabilizes a duplex, triplex or higher order aggregation (e.g., hybridization) of nucleic acids of which the oligomer of the invention is a component. Other components of the solid support include moieties that stabilize aggregations of nucleic acids, e.g., intercalators, minor groove binding moieties, bases modified with a stabilizing moiety (e.g., alkynyl moieties, and fluoroalkyl moieties), and conformational stabilizing moieties, such as those described in commonly owned U.S. Patent Application Publication No. 2007/0059752.
US08466260B2
The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
US08466240B2
Processes for producing high pressure polyethylene and processes for increasing the crosslinkability of high pressure polyethylene are disclosed. The processes comprise controlling particular reaction parameters that have been found to promote crosslinkability in the resulting high pressure polyethylene. High pressure polyethylenes having improved crosslinkability are also disclosed.
US08466237B2
Biodegradable aliphatic/aromatic copolyester comprising: A) an acid component comprising repeating units of: 1) 49 to 63 mol % of an aromatic carboxylic acid; 2) 51 to 37 mol % of an carboxylic acid, at least 50% of which is brassylic acid; B) a diol component; said copolyester being disintegrated according to the Standard ISO 20200 in 90 days.
US08466236B2
The invention provides a fluororesin composition capable of providing a molded article having low relative dielectric constant, excellent in a temperature stability and causing only small transmission losses. The invention is a fluororesin composition wherein a rate of change in relative dielectric constant between 25° C. and 80° C. of a molded article produced therefrom under a standard condition is not greater than 0.2%.
US08466230B2
A water-dispersible polyurethane polymer useful in coating applications preferably includes a backbone having urethane linkages and at least one cycloaliphatic group having a closed aliphatic ring structure. Ethylenically unsaturated groups are preferably provided on the polyurethane polymer.
US08466213B2
The object of the invention is to provide a white ink composition for ink jet textile printing by which even if printing is carried out without discoloring the dye of textile piece, the whiteness degree of a dyed article obtained is high and the dyed article superior in coating film durability and laundering fastness is further obtained without losing the drape of the textile piece. The invention is directed to a white ink composition for ink jet textile printing including a white pigment, a polymer dispersant, an anionic resin emulsion and an aqueous medium, wherein the polymer dispersant is a polymer dispersant (A) obtained by neutralizing a anionic water-soluble resin having a glass transition temperature of 0 to 80° C., an acid value of 100 to 300 mgKOH/g and a mass average molecular weight of 5000 to 30000 with a basic compound, and the anionic resin emulsion is an anionic resin emulsion (B) with a glass transition temperature of at most 0° C, and the mass ratio of the content of the polymer dispersant (A) and that of the anionic resin emulsion (B) is (A)/(B)=1/5 to 1/10 converted to each solid content.
US08466210B2
The present invention relates to a curable dental composition comprising a surfactant and an F-containing compound. The dental composition can be used e.g. as impression material and/or for the production of crown and bridges.
US08466208B2
A curable sheet composition able to follow up a mold shape under the application of heat and pressure, able to polymerize and cure upon being irradiated with light, permitting an optical element molding pattern to be fixed, and comprising 50% to 94% of a polycarbonate diol-modified urethane acrylate oligomer, 5% to 40% of a (meth)acrylate containing at least one carboxyl group in each molecule thereof, and 0.5% to 5% of a photopolymerization initiator.
US08466207B1
Disclosed is a method for making a polyurethane closed-cell foam material exhibiting a bulk density below 4 lbs/ft3 and high strength. The present embodiment uses the reaction product of a modified MDI and a sucrose/glycerine based polyether polyol resin wherein a small measured quantity of the polyol resin is “pre-reacted” with a larger quantity of the isocyanate in a defined ratio such that when the necessary remaining quantity of the polyol resin is added to the “pre-reacted” resin together with a tertiary amine catalyst and water as a blowing agent, the polymerization proceeds slowly enough to provide a stable foam body.
US08466203B2
A method for stabilizing collagenous eye tissues by nitrite and nitroalcohol treatment. The topical stiffening agent contains sodium nitrite or a nitroalcohol in a buffered balanced salt solution and can be applied to the surface of the eye on a daily basis for a prolonged period. Application of the solution results in progressive stabilization of the corneal and scleral tissues through non-enzymatic cross-linking of collagen fibers. The compounds can penetrate into the corneal stroma without the need to remove the corneal epithelium. In addition, ultraviolet light is not needed to activate the cross-linking process. The resulting stabilization of corneal and scleral tissues can prevent future alterations in corneal curvature and has utility in diseases such as keratoconus, keratectasia, progressive myopia, and glaucoma.
US08466196B2
The present invention relates to the field of perfumery. More particularly, it concerns some acetal derivatives of 3-methyl citral of formula (I) wherein the dotted lines indicate the presence of a single or double bond; R1 represents a hydrogen atom or a methyl or ethyl group, R2 represents a hydrogen atom or methyl group; and each R3, taken alone, simultaneously or independently, represents a C1-3 alkyl or alkenyl group; or said R3 groups, taken together, represent a C2-6 hydrocarbon group optionally comprising an oxygen atom. The present invention concerns the use of said compounds in the perfumery industry as well as the compositions or articles containing said compounds.
US08466193B2
Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of histone deacetylase 8 (HDAC8). Also described herein are methods of using such HDAC8 inhibitors, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of HDAC8 activity.
US08466182B2
The present invention relates to compounds of Formula I below and their tautomers or pharmaceutically acceptable salts, compositions and methods of uses thereof.
US08466175B2
The present invention relates to a novel form of the (−)-enantiomer of 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-1H-benzimidazole, i.e. S-omeprazole. More specifically, it relates to a novel form of the magnesium salt of the S-enantiomer of omeprazole trihydrate. The present invention also relates to processes for preparing such a form of the magnesium salt of S-omeprazole and pharmaceutical compositions containing it. Furthermore, the present invention also relates to new intermediates used in the process.
US08466174B2
Ophthalmic compositions and methods of preparing such compositions are disclosed.
US08466173B2
Crystalline polymorphs of (3R)-1-(2-methylalanyl-D-tryptophyl)-3-(phenylmethyl)-3-piperidinecarboxylic acid 1,2,2-trimethylhydrazide which are useful as pharmaceutical agents are disclosed. Methods of production and isolation of these polymorphs and pharmaceutical compositions which include these polymorphs and pharmaceutical methods of treatment are also disclosed. The crystalline polymorphs of the present invention are useful as they act directly on the pituitary gland cells to release growth hormone.
US08466166B2
This invention relates to compounds of the formula (I): or a pharmaceutically acceptable salt thereof, wherein: R1, R2, R3, R4, A and E are each as described herein or a pharmaceutically acceptable salt, and compositions containing such compounds and the method of treatment and the use, comprising such compounds for the treatment of a condition mediated by acid pump antagonistic activity such as, but not limited to, as gastrointestinal disease, gastroesophageal disease, gastroesophageal reflux disease (GERD), laryngopharyngeal reflux disease, peptic ulcer, gastric ulcer, duodenal ulcer, NSAID-induced ulcers, gastritis, infection of Helicobacter pylori, dyspepsia, functional dyspepsia, Zolliπger-Ellison syndrome, non-erosive reflux disease (NERD), visceral pain, cancer, heartburn, nausea, esophagitis, dysphagia, hypersalivation, airway disorders or asthma.
US08466158B2
Compounds of the formula II: wherein R2 is the side chain of leucine, isoleucine, cyclohexylglycine, O-methyl threonine, 4-fluoroleucine or 3-methoxyvaline; R3 is H, methyl or F; Rq is trifluoromethyl and Rq′ is H or Rq and Rq′ define keto; Q is a p-(C1-C6alkylsulphonyl)phenyl- or an optionally substituted 4-(C1-C6alkyl)piperazin-1-yl-thiazol-4-yl-moiety have utility in the treatment of disorders characterized by inappropriate expression or activation of cathepsin K, such as osteoporosis, osteoarthritis, rheumatoid arthritis or bone metastases.
US08466157B2
Disclosed herein is the use of HLM-008182, as well as its analogues formed via in-house synthesis, as a potent proteasome inhibitors. A new method was developed for HLM-008182 through a four-step protocol and the method was further optimized to a two step protocol. The synthesis in both protocols was regioselective with TiCl4. The reaction was highly efficient with microwave assisted heating and THF as solvent. The modification around the molecule HLM-008182 established primary SAR, indicating that the proteasome inhibition activity was a function of the 2-side chain.
US08466156B2
The present invention relates to 2-phenyl-4-cyclopropyl-pyrimidine derivatives and their use as P2Y12 receptor antagonists in the treatment and/or prevention of peripheral vascular, of visceral-, hepatic- and renal-vascular, of cardiovascular and of cerebrovascular diseases or conditions associated with platelet aggregation, including thrombosis in humans and other mammals.
US08466142B2
The present invention provides novel cephalotaxus esters, syntheses thereof, and intermediates thereto. The invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of using said compounds or compositions in the treatment of proliferative diseases (e.g., benign neoplasm, cancer, inflammatory disease, autoimmune disease, diabetic retinopathy) and infectious disease. The invention further provides methods of using said compounds or compositions in the treatment of multidrug resistant cancer.
US08466139B2
The invention relates to a novel sustained release pharmaceutical formulation adapted for administration by injection containing the compound 7α-[9-(4,4,5,5,5-pentafluoropentylsulphinyl)nonyl]oestra-1,3,5(10)-triene-3,17β-diol, more particularly to a formulation adapted for administration by injection containing the compound 7α-[9-(4,4,5,5,5-pentafluoropentylsulphinyl)nonyl]oestra-1,3,5(10)-triene-3,17β-diol in solution in a ricinoleate vehicle which additionally comprises at least one alcohol and a non-aqueous ester solvent which is miscible in the ricinoleate vehicle.
US08466120B2
Compounds, compositions and methods are provided for modulating the levels expression, processing and function of pri-miRNAs. In particular, methods and compounds are provided for the modulation of the levels, expression, processing or function of polycistronic pri-miRNAs. The compositions comprise oligomeric compounds targeted to small non-coding RNAs and pri-miRNAs. Further provided are methods for selectively modulating pri-miRNA levels in a cell. Also provided are methods for identifying oligomeric compounds that result in increase pri-miRNA levels when contacted with a cell.
US08466116B2
This disclosure provides a method of inducing epithelial cell growth. The method includes administering an effective amount of a K-type CpG oligonucleotide, thereby inducing epithelial cell growth. The epithelial cell can be in vivo or in vitro. Methods are also provided for inducing wound healing in a subject. The methods include administering to the subject a therapeutically effective amount of at least one K-type CpG ODN.
US08466113B2
The present invention provides 4-isopropylphenyl glucitol compounds which have no tendency to accumulate in the body and which inhibit SGLT1 activity to suppress postprandial hyperglycemia (or impaired glucose tolerance) through suppression of glucose absorption in the small intestine, whereby the compounds, for example, can suppress the onset of diabetes and metabolic syndrome or can treat these diseases.A 4-isopropylphenyl glucitol compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof: wherein R1 represents a hydrogen atom, etc., R2 represents a methyl group, etc., R3 represents a C1-4 alkyl group substituted with an amino group(s), etc., and R4 represents a hydrogen atom, etc.
US08466111B2
A cyclopenta[g]quinazoline derivative, containing an L-Glu-γ-D-Glu dipeptide group, of formula (I): wherein R1 is amino, C1-4 hydroxyalkyl, C1-4 fluoroalkyl or methoxy-C1-4-alkyl; R2 is hydrogen, C1-4 alkyl, C3-4 alkenyl, C3-4 alkynyl, C2-4 hydroxyalkyl C2-4 halogenoalkyl or C1-4 cyanoalkyl; and Ar is phenylene, thiophenediyl, thiazolediyl, pyridinediyl or pyrimidinediyl which may optionally bear one or two substituents selected from halogeno, hydroxy, amino, nitro, cyano, trifluoromethyl, C1-4 alkyl and C1-4 alkoxy, the compound (I) optionally being in the form of a pharmaceutically acceptable salt or ester; may be used for the treatment of rheumatoid arthritis or acute myeloid leukaemia.
US08466107B2
Fibrin-binding peptides having high binding affinity and excellent physical characteristics compared to previously known fibrin-binding peptides are provided. These fibrin-binding peptides may be conjugated to a detectable label or a therapeutic agent and used to detect and facilitate treatment of pathological conditions associated with the presence of fibrin such as thrombic, angiogenic and neoplastic conditions. These peptides may be used in imaging processes such as MRI, ultrasound and nuclear medicine imaging (e.g. PET, scintigraphic imaging, etc.). The peptides may also be used therapeutically. The present invention also provides processes and methods for making and using such peptides and conjugates thereof.
US08466097B2
The invention relates to flours of plant components, wherein a solution of 10 ml water and 1 ml of an aqueous methylene blue solution of 0.1 wt % brought into contact with 1 g of the flour, comprising an extinction at a wavelength of 660 nm to <1, to a method for producing said flours, products comprising said flours, and the use of the flours for producing skin and hand cleaning agents, surface cleansers, or peeling agents, and the use of the products for cleaning skin, hands, and surfaces.
US08466091B2
Focused libraries of vectors or genetic packages that display, display and express, or comprise a member of a diverse family of antibody peptides, polypeptides or proteins and collectively display, display and express, or comprise at least a portion of the focused diversity of the family. The libraries have length and sequence diversities that mimic that found in native human antibodies.
US08466090B2
A method for high throughput screening of probes is described. These probes are useful for characterization and measurement of unbound metabolites in a fluid sample, particularly characterization and measurement of levels of unbound free fatty acids. By practice of the disclosed invention, a profile of unbound metabolites can be determined for an individual which can be used to determine the individual's relative risk for disease such as stroke, cardiac disease and cancer.
US08466089B2
The present invention provides a novel herbicide showing excellent herbicidal effects, which has a wide application range including agricultural fields and non-agricultural fields and various application methods including soil treatment and foliage treatment. A pyrazole compound represented by the formula (I) or its salt: wherein R1 is alkyl, R2 is a hydrogen atom or alkyl, R3 is alkyl, R4 is alkyl, R5 is alkyl substituted by one alkoxy, alkoxy substituted by one alkoxy, or alkoxycarbonyl, R6 is alkylsulfonyl, A is alkylene substituted by at least one alkyl; a process for its production; a herbicide containing it as an active ingredient; and a method for controlling undesired plants or inhibiting their growth, which comprises applying a herbicidally effective amount thereof to the undesired plants or to a place where they grow.
US08466088B2
Provided is an herbicidal composition which can be applied at a low dose as compared with individual application, and thus is effective to reduce the environmental load on a place where the composition is applied or a periphery thereof, of which the herbicidal spectrum is enlarged, and of which the herbicidal effects last over a long period of time. The herbicidal composition has as active ingredients (a) a herbicidal benzoylpyrazole compound represented by the formula (I) or its salt: wherein Q is —C(O)SR3 or a hydrogen atom, R1 is alkyl or cycloalkyl, R2 is a hydrogen atom or alkyl, R3 is alkyl, cycloalkyl or the like, R4 is alkyl, haloalkyl or the like, R5 is a hydrogen atom, alkyl or the like, R6 is haloalkyl, halogen or the like, and (b) a further herbicidal compound.
US08466087B2
A seed composition comprising a seed and a first component comprising an agriculturally acceptable complex mixture of dissolved organic material characterized by natural organic matter that is partially humified and methods of seed treating. A method comprising contacting a seed with a first component comprising an agriculturally acceptable complex mixture of dissolved organic material characterized by natural organic matter that is partially humified, where the first component enhances at least one of germination, emergence, root development, seedling vigor, seedling growth, mortality resistance, chlorophyll production, cold resistance, water log resistance, and nutrient uptake compared to similar seed not contacted with the first component.
US08466086B2
Manufactured seeds are disclosed that comprise a unit of totipotent plant tissue and a nutritive medium. The nutritive medium can contain a number of different components selected from the following: a gel solute, charcoal, a carbon source, urea, KNO3, NH4NO3, CuCl2, CuSO4, KI, KH2PO4, CaCl2, MgSO4, Na2EDTA, FeSO4, ferric citrate, MnSO4, MnCl2, H3BO3, ZnSO4, CoCl2, Na2MoO4, (NH4)2MoO4, thiamine, riboflavin, pyridoxine, HCl, Ca-pantothenate, nicotinic acid, biotin, folic acid, and myo-inositol. The nutritive medium can also include any of various protein amino acids, any of various polyamines, any of various oxygen-absorbing compounds, any of various non-protein amino acids, and/or a smoke suspension.
US08466085B2
The present invention provides a thermosensitive recording medium, which has a satisfactory color developing sensitivity, an excellent general printability (surface strength) and an excellent anti-sticking property. The thermosensitive recording layer of the thermosensitive recording medium of the present invention contains an alkylketene dimer. Without forming a protecting layer, the thermosensitive recording medium of the present invention is superior in color developing sensitivity, general printability (surface strength) and anti-sticking property.
US08466080B2
A catalyst comprising an aluminosilicate zeolite having an MOR framework type, an acidic MFI molecular sieve component having a Si/Al2 molar ratio of less than 80, a metal component comprising one or more elements selected from groups VIB, VIIB, VIII, and IVA, an inorganic oxide binder, and a fluoride component.
US08466079B2
A method for regenerating at least one impurity-adsorbing sorbent bed includes passing impurity-containing fluid through the impurity-adsorbing bed. The impurity-adsorbing sorbent bed adsorbs an impurity in the impurity-containing fluid to produce a purified fluid. A portion of the purified fluid is sent back through the impurity-adsorbing sorbent bed that contains the adsorbed impurity. The impurity-adsorbing sorbent bed is exposed to microwave energy to desorb the impurity adsorbed on the impurity-adsorbing sorbent bed.
US08466071B2
An object of the present invention is to provide a method for etching a single wafer, which effectively realizes a high flatness of wafer and an increase in productivity thereof. In a method for etching a single wafer, a single thin disk-like wafer sliced from a silicon single crystal ingot is spun, and a front surface of the wafer is etched with an etching solution supplied thereto. In the method, a plurality of supply nozzles are disposed above and opposite to the front surface of the wafer at different portions in the radial direction of the wafer, respectively; and then one or more conditions selected from the group consisting of temperatures, kinds, and supply flow rates of etching solutions from the plurality of supply nozzles are changed.
US08466069B2
According to one embodiment, a method is disclosed for manufacturing a semiconductor device. The method can form a plurality of grooves extending in a first direction on a semiconductor substrate. The method can form an insulating layer on the inner face of the groove and on the top face of the semiconductor substrate. The method can deposit a first conductive layer on the insulating layer so as to fill in the groove. The method can deposit a second conductive layer on the first conductive layer. The method can form a hard mask in a region including part of a region immediately above the groove on the second conductive layer. The method can form a columnar body including the hard mask and the second conductive layer by etching the second conductive layer using the hard mask as a mask.
US08466067B2
Processes for forming high density gap-filling silicon oxide on a patterned substrate are described. The processes increase the density of gap-filling silicon oxide particularly in narrow trenches. The density may also be increased in wide trenches and recessed open areas. The densities of the gap-filling silicon oxide in the narrow and wide trenches/open areas become more similar following the treatment which allows the etch rates to match more closely. This effect may also be described as a reduction in the pattern loading effect. The process involves forming then planarizing silicon oxide. Planarization exposes a new dielectric interface disposed closer to the narrow trenches. The newly exposed interface facilitates a densification treatment by annealing and/or exposing the planarized surface to a plasma.
US08466061B2
A method for forming a through via in a semiconductor element includes providing a semiconductor element having electronic circuitry integrated on the main side thereof. The semiconductor element further includes an etch stop layer and a conductive region, wherein the conductive region is arranged between the etch stop layer and the main side of the semiconductor element. The method also includes selectively etching a through via from a backside of the semiconductor element, opposite to the main side of the semiconductor element, to the etch stop layer and removing at least partly the etch stop layer, so that the conductive region is exposed to the backside and filling at least partly the through via with a conductive material, wherein the conductive material is electrically isolated from the semiconductor element.
US08466060B2
A thin and stackable power MOSFET (SP-MOSFET) and method are proposed. The SVP-MOSFET includes semiconductor substrate with bottom drain metal layer. Formed atop the semiconductor substrate are trenched gate regions and source-body regions. A patterned gate metal layer and source-body metal layer respectively contact trenched gate regions and source-body regions. At least one of through substrate drain via (TSDV), through substrate gate via (TSGV), through substrate source via (TSSV) is provided. The TSDV, formed through semiconductor substrate and in contact with drain metal layer, has top drain contacting pad and bottom drain contacting pad for making top and bottom contacts thereto. Similarly the TSGV, formed through semiconductor substrate and in contact with gate metal layer, has top gate contacting pad and bottom gate contacting pad. Likewise the TSSV, formed through semiconductor substrate and in contact with source-body metal layer, has top source contacting pad and bottom source contacting pad.
US08466057B2
A method of manufacture of an integrated circuit packaging system includes: providing a substrate; forming a via hole in the substrate, the via hole having a top end and a bottom end with the bottom end is larger than the top end; forming a pad on the substrate, the pad encloses the top end of the via hole; and reflowing a conductive filler having higher volume than the via hole over the via hole, the conductive filler having a protrusion extending from the bottom end and the bottom end entirely overlaps at least one surface of the protrusion.
US08466053B2
A gate insulating film is formed on a substrate. Next, a gate electrode film is formed on the gate insulating film. A mask film is formed on a portion of the gate electrode film. The gate electrode film is selectively removed by etching using the mask film as a mask. A gate sidewall film is formed so as to be in contact with the lateral surfaces of the mask film and the gate electrode film. The mask film is formed of a laminated film in which at least a first film, a second film and a third film are laminated in this order. The second film has a higher etching selectivity ratio than that of the third film with respect to the gate sidewall film. The third film has a higher etching selectivity ratio than that of the second film with respect to the gate electrode film.
US08466050B2
A method for forming a lightly doped drain (LDD) region in a semiconductor substrate. The method includes generating an ion beam of a selected species, and accelerating the ion beam, wherein the accelerated ion beam includes a first accelerated portion and a second accelerated portion. The method further includes deflecting the accelerating ion beam, wherein the first and second accelerated portions are concurrently deflected into a first path trajectory having a first deflected angle and second path trajectory having a second deflected angle. In an embodiment, the first and second path trajectories travel in the same direction, which is perpendicular to the surface region of the semiconductor wafer, and the first deflected angle is greater than the second deflected angle. In an embodiment, the selected species may include an n-type ion comprising phosphorous (P), arsenic (As), or antimony (Sb).
US08466045B2
A method for forming strained epitaxial carbon-doped silicon (Si) films, for example as raised source and drain regions for electronic devices. The method includes providing a structure having an epitaxial Si surface and a patterned film, non-selectively depositing a carbon-doped Si film onto the structure, the carbon-doped Si film containing an epitaxial carbon-doped Si film deposited onto the epitaxial Si surface and a non-epitaxial carbon-doped Si film deposited onto the patterned film, and non-selectively depositing a Si film on the carbon-doped Si film, the Si film containing an epitaxial Si film deposited onto the epitaxial carbon-doped Si film and a non-epitaxial Si film deposited onto the non-epitaxial carbon-doped Si film. The method further includes dry etching away the non-epitaxial Si film, the non-epitaxial carbon-doped Si film, and less than the entire epitaxial Si film to form a strained epitaxial carbon-doped Si film on the epitaxial Si surface.
US08466041B2
Provided is a method for manufacturing a lamination type semiconductor integrated device that can simultaneously attain grinding force resistance during back side grinding of a semiconductor wafer, heat resistance during anisotropic dry etching and the like, chemical resistance during plating and etching, smooth debonding of a support substrate for processing at the end, and low adherend staining; the method comprises at least a step of back side grinding of a first semiconductor wafer having a device formed on its surface and a step of laminating by electrical bonding the first semiconductor wafer with a second semiconductor wafer having a device formed on its surface, wherein, at the time of back side grinding of the first semiconductor wafer, back of the first semiconductor wafer is ground after surface of formed device on the first semiconductor wafer is bonded to a support substrate for processing by using a pressure-sensitive silicone adhesive.
US08466038B2
Front-side integrated parts of integrated-circuit chips are produced at locations on a substrate wafer. The front-side parts have a front side. A support wafer having a bearing side is mounted with the bearing side on top of said front-side parts. The support wafer includes at least one weak surface layer. This weak surface layer is attached to the substrate wafer using a retaining adhesive. In one implementation, the weak surface layer is attached to a front surface of the wafer. In another implementation, the weak surface layer is attached to a peripheral edge of the wafer. After attaching the support wafer, back-side integrated parts of the integrated-circuit chips are produced on the substrate wafer. The weak surface layer is then destroyed so as to demount the support wafer from the substrate wafer.
US08466036B2
An integrated circuit chip is formed with an active layer and a trap rich layer. The active layer is formed with an active device layer and a metal interconnect layer. The trap rich layer is formed above the active layer. In some embodiments, the active layer is included in a semiconductor wafer, and the trap rich layer is included in a handle wafer.
US08466031B2
Memory devices and methods of forming include a mixed valent oxide located between a first electrode and a second electrode. Implantation of a metal below a surface of one of the electrodes allows formation of the mixed valent oxide with a direct interface to the electrode. An intermetallic oxide can be subsequently formed between the mixed valent oxide and the electrode by annealing the structure.
US08466017B2
Semiconductor devices and methods of making the devices are described. The devices can be junction field-effect transistors (JFETs) or diodes such as junction barrier Schottky (JBS) diodes or PiN diodes. The devices are made using selective ion implantation using an implantation mask. The devices have implanted sidewalls formed by scattering of normal or near normal incident ions from the implantation mask. Vertical junction field-effect transistors with long channel length are also described. The devices can be made from a wide-bandgap semiconductor material such as silicon carbide (SiC) and can be used in high temperature and high power applications.
US08466015B2
A thin film transistor and a fabrication method thereof, in which one excimer laser annealing (ELA) makes a pixel portion and a driver portion different from each other in surface roughness and grain size. The thin film transistor includes: a substrate including a pixel portion and a driver portion; a first semiconductor layer disposed in the pixel portion and having a first surface roughness; and a second semiconductor layer disposed in the driver portion and having a second surface roughness smaller than the first surface roughness.
US08466007B2
A power semiconductor module includes: an interconnect layer including an electrical conductor patterned on a dielectric layer, the electrical conductor including a power coupling portion having a thickness sufficient to carry power currents and a control coupling portion having a thickness thinner than that of the power coupling portion; and a semiconductor power device physically coupled to the interconnect layer and electrically coupled to the power coupling portion of the electrical conductor.
US08466004B2
Organic photosensitive optoelectronic devices are disclosed. The devises are thin-film crystalline organic optoelectronic devices capable of generating a voltage when exposed to light, and prepared by a method including the steps of: depositing a first organic layer over a first electrode; depositing a second organic layer over the first organic layer; depositing a confining layer over the second organic layer to form a stack; annealing the stack; and finally depositing a second electrode over the second organic layer.
US08465994B2
A method for fabricating a display device having a thin film transistor. When forming wirings and electrode patterns made of a metal layer on a mother substrate, the metal wiring and the electrode patterns are patterned and, simultaneously, the metal layer within a predetermined range of the outermost region of the mother substrate is removed. Removing the metal layer in the outermost region of the mother substrate when patterning the metal layer may obtain stability in the process of fabricating the display device and lower a device failure rate, thereby increasing productivity.
US08465993B2
A vertical cavity surface emitting laser that includes: a substrate; a first semiconductor multilayer reflector; an active region; a second semiconductor multilayer reflector; a columnar structure formed from the second semiconductor multilayer reflector to the first semiconductor multilayer reflector; a current narrowing layer formed inside of the columnar structure and having a conductive region surrounded by an oxidization region; a first electrode formed at a top of the columnar structure, electrically connected to the second semiconductor multilayer reflector and defining a beam window; a first insulating film comprised of a material with a first refractive index and formed on the first electrode to cover the beam window; and a second insulating film comprised of a material with a second refractive index and formed on the first insulating film, of which a radius is smaller than a radius of the conductive region.
US08465982B2
A chromatographic method including chromatographically separating sample ionic species in an eluent stream, detecting the separated sample ionic species, catalytically combining hydrogen and oxygen gases or catalytically decomposing hydrogen peroxide in a catalytic gas elimination chamber, and recycling the effluent stream from the chamber to the chromatography separation column. The residence time between the detector and the chamber is at least about one minute. Also, flowing the recycle sequentially through two detector effluent flow channels of an electrolytic membrane suppressor. Also, applying heat or UV energy between the detector and the chamber. Also, detecting bubbles after the chamber. Also, a Platinum group metal catalyst and ion exchange medium in the chamber. Apparatus for performing the methods.
US08465971B2
Methods and apparatus for controlling biological functions with mechanical vibration are provided. Stimulation is applied to cells of one of an organism, bacteria or virus by mechanical vibration. The biological function comprises biological functions relating to cell growth. The biological functions relating to cell growth may include at least one of cell cultivation, cell proliferation, cell fusion, and cell differentiation.
US08465967B2
A method of trapping a charged particle. The method includes providing a planar substrate having a conductive surface thereon, the conductive surface having at least one non-conductive region. The method also includes applying a solution to the conductive surface, the solution comprising at least one charged particle. The method further includes applying a voltage of a threshold level to the conductive surface. The method also includes, in response to the voltage, generating an electrostatic field in the solution adjacent to a boundary between the conductive surface and the non-conductive region. The method also includes setting the threshold level of voltage to result in a strength of the electrostatic field sufficient to prevent the particle from crossing the electrostatic field.
US08465966B2
The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
US08465965B2
The present invention provides reagents and methods for biomaterial production from cyanobacteria.
US08465953B2
Non-recombinant bacteria that produce ethanol as the primary fermentation product, associated nucleic acids and polypeptides, methods for producing ethanol using the bacteria, and kits are disclosed.
US08465948B2
A polypeptide and polynucleotides comprising at least two carboxy-terminal peptides (CTP) of chorionic gonadotrophin attached to a non-human peptide-of-interest are disclosed. Pharmaceutical compositions comprising the non-human polypeptides and polynucleotides of the invention and methods of using both human and non-human polypeptides and polynucleotides are also disclosed.
US08465946B2
The present invention relates to a microbial expression system for the production of polypeptides based on the use of extrachromosomal DNA, whereby no antibiotic marker genes for the selection of the host cell but DNA sequences that encode glycerine-3-phosphate dehydrogenase are used, and, thus, the production of the desired polypeptide, e.g., xylanase, does not need the addition of antibiotics. The expression system is free from antibiotic-resistance genes. The invention further relates to a DNA sequence that encodes a polypeptide with glycerine-3-phosphate dehydrogenase activity as well as a polypeptide with glycerine-3-phosphate dehydrogenase activity.
US08465942B2
Provided are hydrolases, including lipases, saturases, palmitases and/or stearatases, and polynucleotides encoding them, and methods of making and using these polynucleotides and polypeptides. Further provided are polypeptides, e.g., enzymes, having a hydrolase activity, e.g., lipases, saturases, palmitases and/or stearatases and methods for preparing low saturate or low trans fat oils, such as low saturate or low trans fat animal or vegetable oils, e.g., soy or canola oils.
US08465939B2
Provided is an age-related apolipoprotein B oxidase (apoBNOX) found tightly associated with the low-density lipoprotein particles and believed to be responsible for oxidizing lipoprotein particles and initiating atherogenesis. It causes damage by directly oxidizing the apolipoprotein B protein and indirectly oxidizing the lipids in the particles due to superoxide formation by the apoBNOX and its conversion into hydrogen peroxide. apoBNOX activity is inhibited by tyrosol and hydroxytyrosol and components of white wine, important components of French and Mediterranean diets, which seem to be a very good source of inhibitors of the apolipoprotein B oxidase. Agents comprising at least one naturally-occurring apoBNOX inhibitor and compositions lessen, ameliorate or treat disorders and complications resulting from cell damage caused by oxidation of apolipoprotein B. Also provided is an assay system comprising recombinant apoBNOX or an equivalent peptide and apolipoprotein B purified from human sera as a model to screen for agents and supplements that lower apoBNOX activity when administered orally.
US08465935B2
The invention relates to the detection and quantitation of cyclodextrins and cyclodextrin derivatives in solutions comprising a protein. The invention further relates to methods of evaluating pharmaceutical preparations for the presence of residual cyclodextrins.
US08465921B2
Conjugates between a minor groove binding molecule, such as the trimer of 1,2-dihydro-(3H)-pyrrolo[3,2-e]indole-7-carboxylate (CDPI3), and an oligonucleotide form unusually stable hybrids with complementary target sequences, in which the tethered CDPI3 group resides in the minor groove of the duplex. These conjugates can be used as probes and primers. Due to their unusually high binding affinity, conjugates as short as 8-mers can be used as amplification primers with high specificity and efficiency. MGB conjugation also increases the discriminatory power of short oligonucleotides, providing enhanced detection of nucleotide sequence mismatches by short oligonucleotides. The MGB-conjugated probes and primers described herein facilitate various analytic and diagnostic procedures, such as amplification reactions, PCR, detection of single-nucleotide polymorphisms, gene hunting, differential display, fluorescence energy transfer, hydrolyzable probe assays and others; by allowing the use of shorter oligonucleotides, which have higher specificity and better discriminatory power.
US08465920B2
The invention relates to a method for manipulating, isolating, detecting or amplifying a target nucleic acid in a sample by hybridization with an oligonucleotide-oligocation conjugate, comprising allowing said nucleic acid to react with an oligonucleotide-oligocation conjugate comprising at least A1 and Bj linked together directly or via a linker, wherein. A, is an i-mer oligonucleotides, with i=3 to 50, where Ai is an oligomer with naturally or non naturally occurring nucleobases and/or pentafuranosyl groups and/or native phosphodiester bonds, optionally comprising a marker group. Bj is a j-mer organic oligocation moiety, with j=1 to 50, where B is —HPO3—R1—(NH—R2)n—NH—R3—O—, where R1, R2 and R3 are lower alkylene, identical or different, NH—R2 moieties being identical or different when n is >1; HPO3—R1—CH(X)—R3—O—, where Ri and R3, identical or different, are lower alkylene and X is putrescine, spermidine or spermine residue.
US08465919B2
The method for detecting a methylated cytosine of the present invention comprises the steps of: hybridizing a sample DNA with an oligonucleotide which can hybridize with a region of the sample DNA containing a cytosine suspected of being methylated and has an a basic site at the position complementary to the cytosine; reacting the hybridized sample DNA obtained in the previous step with an oxidizing agent to oxidize the cytosine when it is methylated; and detecting the oxidized methylated cytosine.
US08465916B2
The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at least one variance in the kinase domain of the erbB1 gene confers sensitivity to the tyrosine kinase inhibitor gefitinib. Thus, a diagnostic assay for these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.
US08465915B2
The invention relates to efficient, high-throughput methods, systems, and DNA constructs for identification and isolation of transcription termination sequences. The invention relates further to specific terminator sequences identified by the methods isolated from rice.
US08465903B2
Methods for forming photoresists sensitive to radiation on a substrate are provided. Described are chemical vapor deposition methods of forming films (e.g., silicon-containing films) as photoresists using a plasma which may be exposed to radiation to form a pattern. The deposition methods utilize precursors with cross-linkable moieties that will cross-link upon exposure to radiation. Radiation may be carried out in the with or without the presence of oxygen. Exposed or unexposed areas may then be developed in an aqueous base developer.
US08465890B2
An electrophotographic photoconductor comprising a conductive support, an undercoat layer and a photosensitive layer, the undercoat layer and the photosensitive layer being formed on the conductive support in sequence, wherein the undercoat layer contains a binder resin, titanium oxide particles surface-treated with at least anhydrous silicon dioxide and titanium oxide particles surface-treated with at least hydrous silicon dioxide.
US08465885B2
A method for forming anti-boundary layer patterns includes patterning a first masking layer on a chrome layer, etching to remove portions of the chrome layer and expose portions of a first quartz layer, removing the first masking layer, patterning a second masking layer on portions of the chrome layer and the first quartz layer, and etching to remove exposed portions of the first quartz layer and to expose portions of an etch stop layer to define anti-boundary layers defined by the first quartz layer and the etch stop layer.
US08465884B2
A method of depicting a photomask using e-beams includes preparing a photomask having an e-beam resist, depicting the e-beam resist and forming an e-beam resist pattern on the photomask. Depicting the e-beam resist includes irradiating e-beams to an e-beam depiction region without irradiating the e-beams to an e-beam non-depiction region disposed in the e-beam depiction region. The e-beam depiction region and the e-beam non-depiction region are formed using an e-beam resist pattern having the same polarity.
US08465882B2
A membrane-electrode assembly for a solid polymer electrolyte fuel cell includes a proton-conductive composite membrane including a reinforcing sheet and an electrolyte membrane. The reinforcing sheet has through-holes extending in a thickness direction of the reinforcing sheet. The through-holes are provided in a portion other than an edge of the reinforcing sheet in an in-plane direction. An anode electrode layer is provided on one surface of the proton-conductive composite membrane. A cathode electrode layer is provided on another surface of the proton-conductive composite membrane. At least one of an edge of the anode electrode layer and an edge of the cathode electrode layer in the in-plane direction is arranged outside in the in-plane direction with respect to the portion in which the plurality of through-holes are provided.
US08465880B2
There has been a problem that the cell units cannot bear the load exerted on the units while being stacked since a fuel cell stack including a refrigerant channel formed between cell units each having an even number of electrolyte/electrode structures (MEA) and metal separators which are alternated does not have any structure supporting the separators forming the refrigerant channel in a stacking direction. In order to solve the above problem, in each of a first power generating unit and a second power generating unit, projections formed at the buffer portions of the separators are disposed in the same positions in the stacking direction with the MEA interposed therebetween. Since between the first and second power generating units, the projections of the buffer portions are staggered, the projections of the first and second power generating units are thereby disposed in the same positions in the stacking direction.
US08465877B2
A F-type electrochemical cell, which is a lithium air battery, includes a positive electrode facing a negative electrode composed of metallic lithium with a separator provided therebetween in a casing. Air is capable of flow to the positive electrode. A nonaqueous electrolytic solution is charged into a space between the positive electrode and the negative electrode. At least one of the positive electrode and the nonaqueous electrolytic solution of the lithium air battery contains a compound having a stable radical skeleton. The compound also serves as a redox catalyst for oxygen.
US08465876B2
A process for the utilization of the methane produced by enteric fermentation, specifically to a process that utilizes methane produced by ruminant animals through enteric fermentation as a source of carbon and/or energy for the directed production of methane-based goods or processes is provided.
US08465867B2
A large-capacity battery module may be formed by integrating a plurality of unit cells. The present invention provides a secondary battery module having a plurality of unit cells and connectors for electrically connecting the unit cells, which includes: a spacer set up between the unit cells and the connectors. The secondary battery module can insulate a cap from a connector and maintain a uniform space between the unit cells.
US08465861B2
A battery pack includes: a battery including a battery element covered with a packaging member, the battery element including a positive electrode and a negative electrode which are spirally wound together or stacked on one another through a separator; a protection circuit board for the battery; and a covering material collectively covering the battery and the protection circuit board. The covering material includes a shape-retaining polymer. The shape-retaining polymer contains an insulating curable polyurethane resin including polyol and polyisocyanate.
US08465860B2
A primary cell having an anode comprising lithium or lithium alloy and a cathode comprising iron disulfide (FeS2) and carbon particles. The electrolyte comprises a lithium salt dissolved in an organic solvent mixture. The electrolyte contains between about 100 and 2000 parts by weight water per million parts by weight (ppm) electrolyte therein. The electrolyte may contain between about 200 and 2000, or between about 500 and 2000 parts by weight water per million parts by weight electrolyte. A cathode slurry is prepared comprising iron disulfide powder, carbon, binder, and a liquid solvent. The mixture is coated onto a conductive substrate and solvent evaporated leaving a dry cathode coating on the substrate. The anode and cathode can be spirally wound with separator therebetween and inserted into the cell casing with electrolyte then added.
US08465859B2
A current sensor includes a magnetic balance sensor and a switching circuit. The magnetic balance sensor includes a feedback coil which is disposed near a magnetic sensor element varying in characteristics due to application of an induction field caused by measurement current and which produces a canceling magnetic field canceling the induction field. The switching circuit switches between magnetic proportional detection and magnetic balance detection. The magnetic proportional detection is configured to output a voltage difference as a sensor output. The magnetic balance detection is configured to output, as a sensor output, a value corresponding to current flowing through the feedback coil when a balanced state in which the induction field and the canceling magnetic field cancel each other out is reached after the feedback coil is energized by the voltage difference.
US08465853B2
A hard drive platter comprises a substrate that includes glassy metal. At least one magnetic layer is arranged on the substrate. The glassy metal includes at least three of zirconium, titanium, nickel, copper, and/or beryllium. A perpendicular recording system comprises the hard drive platter. A hard disk drive comprises the hard drive platter. A computer comprises the hard disk drive. A digital camera comprises the hard drive platter. A portable media player comprises the hard drive platter. An insulating layer and/or an Aluminum layer may be located between the glassy metal substrate and the at least one magnetic layer.
US08465848B2
This invention relates to electroluminescent benzofluorenes that are useful in electroluminescent applications. It also relates to electronic devices in which the active layer includes such a benzofluorene composition.
US08465840B2
The present invention relates to the use of a polyurethane system, comprising (a) polyisocyanates, (b) at least one isocyanate-reactive compound, (c) at least one carboxylic salt of an amine catalyst, where, based on one equivalent of the amine of the amino catalyst, from 0.5 to 1.5 equivalents of acid groups of a carboxylic acid are comprised, (d) if appropriate, further catalysts, (e) if appropriate, a reactive chain extender having at least two groups reactive toward isocyanates, where at least one group reactive toward isocyanates is a free, primary, NH2 group, and (f) if appropriate, further additives, for the production of polyurethane sandwich components. The present invention further relates to a process for the production of polyurethane sandwich components, and also to the polyurethane sandwich components obtained by the process of the invention.
US08465834B2
A conductive pressure sensitive adhesive tape is provided. The conductive pressure sensitive adhesive tape includes a first metal foil, a polymer film attached to a surface of the first metal foil with a polymer binder interposed therebetween, a second metal foil attached to a surface of the polymer film with a polymer binder interposed therebetween, and a polymer adhesive layer formed on a backside of at least one of the first and second metal foils.
US08465829B2
The invention is directed to a method of positioning nanoparticles on a patterned substrate. The method comprises providing a patterned substrate with selectively positioned recesses, and applying a solution or suspension of nanoparticles to the patterned substrate to form a wetted substrate. A wiper member is dragged across the surface of the wetted substrate to remove a portion of the applied nanoparticles from the wetted substrate, and leaving a substantial number of the remaining portion of the applied nanoparticles disposed in the selectively positioned recesses of the substrate. The invention is also directed to a method of making carbon nanotubes from the positioned nanoparticles.
US08465820B2
A casing of a solid-propellant engine comprising a core and a layer of elastomeric material, set as coating for at least part of the core to provide a thermal protection of the core itself is obtained by: inserting the core in a forming mold so as to make within the mold two annular chambers separated from one another by the core; forming a strand of elastomeric material; obtaining a defined portion of elastomeric material by cutting the strand transversely to size in an external environment; and injecting the cut portion of elastomeric material simultaneously within both of the annular chambers.
US08465818B2
A polymer composition and wall of a container made from such composition is set forth comprising a polyamide and polyester and a sufficient amount of an interfacial tension reducing agent such that the polyamide domains stretch disproportionately to the amount of stretch experienced by the polyester both with and without a cobalt salt.
US08465816B2
A pressure pipe resin is disclosed comprising from 90 to 99.9 wt %, based on the total weight of the resin, of a polyethylene, and from 0.1 to 10 wt %, based on the total weight of the blend, of an ionomer.
US08465809B2
A moving bed reactor system is provided. The system comprises at least one gas inlet, a distributor, a temperature control, a plurality of electrodes, and a spark control circuit. The spark control circuit drives the electrodes and generates a multi-arc discharge when the system is loaded with particles and a gas at approximately atmospheric pressure or greater is being pumped through the system. The multi-arc discharge is useful to create activated species which may improve the rate of a chemical reaction taking place in the moving bed reactor system.
US08465808B2
A process for modifying a surface of a metal is provided. The process includes providing a metal surface having a metal oxide, contacting the metal oxide with an organic acid having a hydroxamic acid, a sulphonic acid, or a carboxylic acid functional group, and depositing the organic acid on the surface of the metal oxide for providing a modified metal surface. Modified metal compositions are disclosed having a metal surface or a metal alloy surface having a metal oxide, and an organic acid having a functional group that is deposited onto the surface of the metal oxide forming a self assembled monolayer, multiple monolayers, or a film of a sulphonate, a hydroxamic acid, or a carboxylate with —COOH, —OH and —NH2 terminal tail groups on the native oxide surface of the metal or the metal alloy.
US08465798B2
Disclosed is a method for manufacturing a fluorescent material. The method includes: putting the fluorescent material into a first solution, and agitating the fluorescent material and the first solution; putting a nano fluorescent material having a nano size into the first solution, and agitating the nano fluorescent material having a nano size and the first solution; and separating supernatant from the first solution including the fluorescent material, and drying the fluorescent material. Disclosed is a light emitting device. The light emitting device includes: a body; a light emitting element mounted on a cavity formed in the body; a resin formed in the cavity; and a fluorescent material added to the resin, wherein a nano fluorescent material having a nano size is adsorbed in the fluorescent material.
US08465783B2
Provided is a magnesium rich composition including potassium, magnesium and citrate, a method for producing such a composition and food or nutritional product including the composition.
US08465780B2
The specification discloses a borate microemulsion product. In one embodiment, the borate microemulsion includes from about 24 to about 32 weight percent emulsified sodium pentaborate; and from about 24 to about 32 weight percent particulate boric acid suspended therein. The microemulsion has a density of about 9.5 to about 10.5 pounds per gallon at about room temperature. In certain embodiments, the microemulsion has a viscosity of about 1200 to about 1520 at a temperature of from about 66° F. to about 70° F. In certain other embodiments, microemulsion has a viscosity of about 1000 to about 3000 at a temperature of from about 70° F. to about 75° F.
US08465779B2
Generally, hydrogels are prepared by forming a liquid reaction mixture that contains a) monomer(s) and/or polymer(s) at least portion(s) of which are sensitive to environmental changes (e.g., changes in pH or temperature), b) a crosslinker and c) a polymerization initiator. If desired, a porosigen may be incorporated into the liquid reaction mixture to create pores. After the hydrogel is formed, the porosigen is removed to create pores in the hydrogel. These hydrogels may be prepared in many forms including pellets, filaments, and particles. Biomedical uses of these hydrogels include applications wherein the hydrogel is implanted in the body of a patient and an environmental condition at the implantation site causes the hydrogel to expand in situ.
US08465775B2
A plurality of artificial red blood cell particles includes each particle of the plurality being substantially monodisperse and each particle having a largest common linear dimension of about 5 μm to about 10 μm. The particles can also have a modulus configured such that a particle of the plurality of particles can pass through a tube having an inner diameter of less than about 3 μm.
US08465773B2
Compositions for forming a self-reinforcing composite biomatrix, methods of manufacture and use therefore are herein disclosed. Kits including delivery devices suitable for delivering the compositions are also disclosed. In some embodiments, the composition can include at least three components. In one embodiment, a first component can include a first functionalized polymer, a second component can include a second functionalized polymer and a third component can include silk protein or constituents thereof. In some embodiments, the composition can include at least one cell type and/or at least one growth factor. In some embodiments, the composition can include a biologic encapsulated, suspended, disposed within or loaded into a biodegradable carrier. In some embodiments, the composition(s) of the present invention can be delivered by a dual lumen injection device to a treatment area in situ, in vivo, as well as ex vivo applications.
US08465768B2
Disclosed is a pharmaceutical composition for release control comprising a plurality of particles for release control. The plurality of particles for release control comprise a core material containing methylphenidate and a polymer coating layer for release control formed on the core material. The plurality of particles for release control are divided into two or more groups based on the average thickness of the polymer coating layer for release control. The particle groups are identical in terms of the composition of the polymer in the polymer coating layer, but are different in terms of the average thickness of the coated layer. The pharmaceutical composition for release control according to the present invention may control the release pattern of methylphenidate contained in the core material as desired, and can be used as an oral formulation in a variety of forms such as orally disintegrating tablets, etc.
US08465758B2
A method of producing an intravascular stent has a coat comprising a crosslinked amphiphilic polymer and a sparingly water soluble matrix metalloproteinase inhibitor (MMPI). Preferably the polymer is formed from 2-methacryloyloxy-2′-ethyltrimethylammonium phosphate inner salt, C4-18 alkyl methacrylate and reactive and/or crosslinking monomer and the MMPI is a hydroxamic acid, more preferably batimastat. Preclinical and clinical results are reported, showing good luminal areas and reduced intimal thickening.
US08465754B2
An objective of the present invention is to provide a whole-cell bacterial vaccine composition for preventing whooping cough caused by Bordetella parapertussis, comprising whole cells, whole-cell homogenate, or cell lysate of B. parapertussis as an immunogen, and methods for producing them.
US08465745B2
Disclosed herein are compositions and methods for eliciting immune responses against antigens. In particular embodiments, the compounds and methods elicit immune responses against antigens that are otherwise recognized by the host as “self” antigens. The immune response is enhanced by presenting the host immune system with a chimeric antigen comprising an immune response domain and a target binding domain, wherein the target binding domain comprises a xenotypic antibody fragment. By virtue of the target binding domain, antigen presenting cells take up, process, and present the chimeric antigen, eliciting both a humoral and cellular immune response.
US08465738B2
The present invention is directed to a method of inhibiting tumor formation in a cancer patient at a site remote from sites of prior tumor formation and to a method of preventing metastases. These methods involve administering to the cancer patient an inhibitor of vascular endothelial growth factor receptor 1+ bone marrow-derived cells under conditions effective either to inhibit tumor formation in the cancer patient at a site remote from sites of prior tumor formation or to prevent metastases. Candidate compounds useful for such purposes can be screened depending on whether they bind to vascular endothelial growth factor receptor 1+ bone marrow-derived cells. Metastases in a cancer patient can be monitored by evaluating a patient sample for detection and quantification of vascular endothelial growth factor receptor 1+ bone marrow-derived cells and comparing the level of vascular endothelial growth factor receptor 1+ bone marrow-derived cells to prior levels.
US08465733B2
Disclosed are a method for producing a frozen pharmaceutical composition prepared from cultured human mesenchymal stem cells and a pharmaceutical composition containing human mesenchymal stem cells. This method is a method for producing a frozen pharmaceutical composition containing human mesenchymal stem cells, which comprises the following steps in this order: (a) adding trypsin to human mesenchymal stem cells in a culture vessel to detach the cells from the surface of the culture vessel; (b) adding a bicarbonate Ringer's solution containing human serum albumin to the detached cells to terminate the reaction with trypsin, and washing the cells with the bicarbonate Ringer's solution containing human serum albumin; (c) suspending the cells in a bicarbonate Ringer's solution containing human serum albumin and dimethyl sulfoxide; (d) putting the resulting suspension in a container which allows freezing of what is contained therein, and sealing the container; and (e) freezing the suspension put in the container.
US08465731B2
A probiotic color cosmetic composition comprising at least one extract from a probiotic microorganism; at least one non-clay lamellar phyllosilicate mineral particulate; and at least one anti-inflammatory ingredient present in an amount sufficient to inhibit one or more of the pathways that contribute to skin inflammation; and a method for treating skin for improvement by applying to skin in need of such improvement the composition of the invention.
US08465730B1
The present invention is directed toward a series of polyesters with tunable ascetics and skin conditioning properties for use in cosmetic formulation, specifically sun screening formulations in which the performance is improved by a synergistic effect between the sunscreening actives and the polyester. These novel polyglycerol polyesters are designed to be multidimensional. The physical properties and aesthetics of the current invention can be tuned rapidly by controlling the ratio of fatty groups, as well as the cross-linker used. The resulting polyglycerol polyesters have outstanding aesthetics and physical properties.
US08465726B2
This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits.
US08465724B2
Described herein are compounds, pharmaceutical compositions and methods for treating pathogenic cell populations in a patient. The compounds described herein include conjugates of a plurality of cytotoxic drugs and vitamin receptor binding ligands. The plurality of drugs may be the same or different. Similarly, the vitamin receptor binding ligands may be the same or different. The conjugates also include a linker that is formed from one or more spacer linkers, heteroatom linkers, and releasable linkers.
US08465709B2
There is provided a retention mechanism for an immersion medium, for use in a device which observes/measures a sample by use of an immersion objective lens, includes a member which retains the immersion medium near a tip portion of the objective lens, wherein the member is configured to include at least first and second materials.
US08465701B2
Provided is a catalyst material comprising aggregates of nanoneedles of mainly R-type manganese dioxide and having a mesoporous structure. With this, water can be oxidatively decomposed under visible light at room temperature to produce oxygen gas, proton and electron. Also provided is a catalyst material comprising aggregates of nanoparticles of mainly hydrogenated manganese dioxide. With this, acetic acid or an inorganic substance can be synthesized from carbon dioxide gas.
US08465690B1
A fluid inversion liner apparatus controls fluid loss to permit lining of pipe in smaller spaces by requiring less fluid. The apparatus includes a housing, a liner feeding assembly, and a nozzle. A tubular flexible liner is insertable through the liner feeding assembly. The liner has a first end couplable to the nozzle forming a fluid seal at the nozzle. A fluid injection port is provided for introducing fluid such as air or water into the housing. The liner feeding assembly is adjustable for conforming to the liner as the liner passes through the liner feeding assembly. Thus, fluid introduced into the housing through the fluid injection port is prevented from passing out of the housing through the liner feeding assembly. As a result, fluid pressure between the interior of the housing and the liner draws the liner through the liner feeding assembly and out of the nozzle.
US08465674B2
A compound represented by the formula (1) is provided. In the formula (1), for example, R1 and R2 are alkyl having 1 to 10 carbons, alkoxy having 1 to 9 carbons or alkenyl having 2 to 10 carbons; the ring A and the ring B are 1,4-cyclohexylene or 1,4-phenylene; Z1 and Z2 are a single bond and Z3 is —CH2O— or —OCH2—; Y1 and Y2 are halogen, —CF3, —CHF2, —CH2F, —OCF3, —OCHF2 or —OCH2F; and m and n is 0, 1 or 2, p is 1 or 2, and the sum of m, n and p is 1, 2 or 3.
US08465671B2
There is provided a novel dichroic dye having liquid crystal properties, dichroic properties and polymerizable reactivity, the dichroic dye being used to form a color filter layer having excellent physical properties such as dichroic ratio, heat resistance, durability, high contrast ratio and polarizing properties, a composition comprising the same for color filter, a color filter array plate (an upper plate) prepared therefrom, and a liquid crystal display comprising the color filter array plate. The dichroic dye has a structure of R1-L1-M-L2-D (wherein, D is a dichroic structure, M is a structure with liquid crystal properties, R1 is a reactive end functional group, and L and L1 are linking structures that link R1, M, and D), and the composition for forming a color filter layer includes the dichroic dye. Also, the color filter array plate, which comprises color filter layer formed of the composition of this invention and the liquid crystal display, which comprise the color filter array plate but does not requires an upper alignment film and/or a polarization plate are provided. The color filter array plate and the liquid crystal display comprising the same have excellent physical properties such as durability, polarizing degree, resolution and contrast ratio.
US08465657B2
Disclosed are a damascene and dual damascene processes both of which incorporate the use of a release layer to remove trace amounts of residual material between metal interconnect lines. The release layer is deposited onto a dielectric layer. The release layer comprises an organic material, a dielectric material, a metal or a metal nitride. Trenches are etched into the dielectric layer. The trenches are lined with a liner and filled with a conductor. The conductor and liner materials are polished off the release layer. However, trace amounts of the residual material may remain. The release layer is removed (e.g., by an appropriate solvent or wet etching process) to remove the residual material. If the trench is formed such that the release layer overlaps the walls of the trench, then when the release layer is removed another dielectric layer can be deposited that reinforces the corners around the top of the metal interconnect line.
US08465651B2
A sustainable method and system for treating and maintaining bodies of water at low cost for low density recreational use is disclosed. A system of the invention generally includes at least one containing means, at least one coordination means, at least one chemical application means, at least one non-intrusive mobile suction means, and at least one filtration means. The coordinating means can receive information regarding water quality parameters that are controlled, and can timely activate the processes necessary to adjust the water quality parameters within their respective limits. The disclosed methods and system filter only a small fraction of the total water volume, up to 200 times less per day than the flow filtered by conventional swimming pool filtration systems. The disclosed methods and system also use less chemicals, up to 100 times less than conventional swimming pool water treatment systems. The methods and system of the present invention can be used to treat recreational water bodies affected by bacteria and microalgae and provide sustainable methods for producing water that complies with bacteriological and physicochemical requirements for recreational water, as set forth by governmental regulatory agencies such as the Environmental Protection Agency (EPA), for bathing with full body contact.
US08465640B2
Elimination and/or mitigation of fouling in a vapor transport systems, such as vent lines and scrubber feed lines may be accomplished using an antifouling additive. The method for employing the antifouling additive includes introducing into the vapor transport system an additive including a polar solvent and corrosion inhibitor wherein: the vapor transport system is substantially water free; the vapor transport system is used to transport acidic materials; the additive is a liquid at vapor transport system operating conditions; and the additive is stable at the vapor transport system operating conditions.
US08465639B2
A system, and corresponding method for use, for providing a mass-producible retroreflective material, or sheeting, featuring full cube corner pins is presented. The full cube corner shaping may be provided with the use of a diamond turning tool. The diamond turning tool may be used to simultaneously manufacture a number of pins. The pins may be used to form a mold featuring a triangular or full cube corner surface formation.
US08465622B2
The present invention relates to a sizing composition that, when applied to paper substrate, creates a substrate, preferably suitable for inkjet printing, having increased print density, enhanced print mottle, as well as print sharpness, low HST, and/or image dry time, the substrate preferably having high brightness and reduced color-to-color bleed as well. In addition, the present invention relates to a method of reducing the HST of a paper substrate by applying the sizing composition to at least one surface thereof. Further, the application relates to methods of making and using the sizing composition, as well as methods of making and using the paper containing the sizing composition.
US08465620B2
The plasma processing apparatus includes a plasma chamber, a first electrode, a second electrode, and a plasma containment device. The plasma containment device has a plurality of slots and is electrically coupled to the first electrode. The containment device is configured to confine plasma within an inter-electrode volume while facilitating maximum process gas flow. When plasma is generated by applying electric fields to process gas within the inter-electrode volume, the containment device electrically confines the plasma to the inter-electrode volume without significantly restricting the flow of gas from the inter-electrode volume.
US08465616B2
A method for making a housing comprising: providing a metal layer, a decorative layer, and an adhesive layer; attaching the adhesive layer to the decorative layer; attaching the adhesive layer to the metal layer to form a intermediate product; and punching the intermediate product by a stamping mold to form the housing. The application also discloses a housing used in a portable electronic device.
US08465612B2
In this manufacturing method, a tubular body 18 having a rib 16 provided therein is obtained. The manufacturing method includes the steps of: preparing a mandrel 2 divided into two or more divided bodies d1 along a longitudinal direction of the mandrel 2; winding a prepreg r1 for a rib around at least one of the divided bodies d1; combining all the divided bodies d1 to obtain a first intermediate body 10 after the step of winding the prepreg r1 for the rib; winding a prepreg g1 for the outer peripheral part around an outside of the first intermediate body 10 to obtain a second intermediate body; heating the second intermediate body to obtain a cured laminate; and extracting the mandrel 2 from the cured laminate. Preferably, the mandrel is equally divided in a circumferential direction. Preferably, a winding start end part t2 of the prepreg r1 for the rib and a winding finish end part t1 thereof overlap with each other.
US08465611B2
A nonwoven fabric is provided having a plurality of semi-crystalline filaments that are thermally bonded to each other and are formed of the same polymer and exhibit substantially the same melting temperature. The fabric is produced by melt spinning an amorphous crystallizable polymer to form two components having different levels of crystallinity. During spinning, a first component of the polymer is exposed to conditions that result in stress-induced crystallization such that the first polymer component is in a semi-crystalline state and serves as the matrix or strength component of the fabric. The second polymer component is not subjected to stress induced crystallization and thus remains in a substantially amorphous state which bonds well at relatively low temperatures. In a bonding step, the fabric is heated to soften and fuse the binder component. Under these conditions, the binder component undergoes thermal crystallization so that in the final product, both polymer components are semi-crystalline.
US08465601B2
A high carbon steel sheet having superior strength and ductility and a method for manufacturing the same comprising: 0.2 to 1.0 wt % carbon (C), 0 to 3.0 wt % silicon (Si), 0 to 3.0 wt % manganese (Mn), 0 to 3.0 wt % chromium (Cr), 0 to 3.0 wt % nickel (Ni), 0 to 0.5 wt % molybdenum (Mo), 0 to 3.0 wt % aluminum (Al), 0 to 0.01 wt % boron (B), 0 to 0.5 wt % titanium (Ti), and the remainder substantially being iron (Fe) and inevitable impurities. The contents of carbon, manganese, chromium, and nickel satisfy the following Equation 1, and the contents of silicon and aluminum satisfy the following Equation 2: (3.0−2.5×C)wt %≦(Mn+Cr+Ni/2)≦8.5 wt %—(Equation 1) Si+Al>1.0 wt % (Equation 2).
US08465597B2
A modular recycling cleaning system comprising in combination: a pressure washing and control module, a vacuum motor assembly module, a reservoir module, an air/liquid separator module, a flexible hose system, a control system and a cleaning head, capable of being easily configured so as to function as any one of: a straight through pressure washer with cleaning liquid supplied from an external source; a straight through pressure washer with cleaning liquid supplied internally from an integral water reservoir; a recycling pressure washer with cleaning liquid being supplied and reused from an integral cleaning liquid reservoir replenished with cleaning liquid by means of a vacuum recovery system; a straight through pressure washer with recovery of contaminated cleaning liquid but without reuse; a conventional wet vacuum cleaning system or a conventional dry vacuum cleaning system. The appliance being capable of further configuration as a shampooing machine. Further preferred embodiments of the invention include the possible integration of a vane separator and/or a HEPA filter on the vacuum system exhaust; a coacting switch and control for the pressure pump and the vacuum recovery system such that maximum electric current draw remains below a threshold; IPX5 water resistance of the system; various filtering arrangements for both the air and the liquid drawn into the system and a compact coaxial hose set connecting the cleaner body to the hand piece.
US08465584B2
An aqueous slurry of finely divided fillers which are at least partly coated with anionic latices, wherein the slurry is obtainable by treating an aqueous slurry of finely divided fillers with an aqueous dispersion comprising at least one anionic latex and at least one degraded starch, preparation of the aqueous slurries and their use as an additive to the paper stock in the production of filler-containing paper, filler-containing cardboard or filler-containing board by draining the paper stock.
US08465578B2
A process for printing an image includes printing a substrate with an aqueous inkjet ink and drying the printed image with a near-infrared drying system, wherein the inkjet ink is a yellow or magenta inkjet ink and comprises a yellow or magenta colorant and a distinct near-infrared absorbing compound. Inkjet ink sets for use with an inkjet printing system employing a near-infrared drying system in the process include at least a black ink and a yellow ink, wherein the yellow ink comprises a yellow colorant and dispersed nanoparticulate colloidal silica at a concentration of from 0.1 to about 10 wt %, and the black ink comprises a black colorant and dispersed nanoparticulate colloidal silica at a concentration of from 0 wt. % to at most ½ of the wt. % of the dispersed nanoparticulate colloidal silica in the yellow ink. Various embodiments provide a process for inkjet printing and drying inks with improved absorption in the near-IR region of the spectrum for improved drying performance of aqueous, hypsochromic inks, and an inkjet ink set with improved balanced near-IR drying of black and yellow inkjet inks.
US08465577B2
A novel black ink composition is provided. In the black ink composition of the present invention, the dye compounds include a blue dye compound of formula (I), a red dye compound of formula (II) and a yellow dye compound of formula (III). The black ink composition of the present invention is suitable for inkjet printing to improve light-fastness and printing property.
US08465575B2
Disclosed is a dust collector (30) that is disposed in an air passageway (15) to which water droplets (21a) are supplied, and that includes a dust collecting electrode portion (31b) which electrically attracts dust charged in the air. The dust collecting electrode portion (31b) is made of a plate-like member having a mesh-like structure with a plurality of pores, thereby reducing an interfacial tension between the water droplets (21a) adhering on the surface of the dust collecting electrode portion (31b) and the dust collecting electrode portion (31b). Thus, water droplets are prevented from increasing in size on the surface of a dust collecting electrode, and a decrease in the dust collection capability due to adhesion of dust or the like is reduced.
US08465574B2
The present invention relates to an electrostatic filter. Particularly but not exclusively the invention relates to an electrostatic filter for removing dust particles, for example an electrostatic filter for use in a vacuum cleaner, fan or air conditioner. The electrostatic filter includes a filter medium located between a first and a second electrode, each at a different voltage during use, such that a potential difference is formed across the filter medium, the first and second electrodes being substantially non-porous.
US08465572B1
A horizontal heater treater tank for separating petroleum mixtures. An inlet on one end of the tank and gas, water, and oil outlets provided on an opposite end, with each outlet having a vortex breaker. The inlet communicating with a c-shaped inlet diverter where gas separates into the top of a heating section and the fluids flow to the bottom of the heating section. Sediment collects in the bottom of the heating section and is removed via a sand trap. Water remains at the bottom of the tank, and oil completely surrounds a horizontally oriented u-shaped firetube which heats the oil. The fluids flow through a perforated baffle then a bent lamella separator before entering a settling portion of the tank where gas and water exit via the gas and water outlets and oil flows over an oil weir and exits via the oil outlet downstream of the weir.
US08465567B2
The present invention relates to a method for the production of stable humus- and nutrient-rich and water-storing soil substrates with properties of anthropogenic soil types (Terra Preta) in which pyrogenic carbon, organic biomass, and/or natural mineral materials are used as initial materials in a fermentation process. The soil produced or treated according to the invention leads to a sustainably high soil yield such that mineral fertilizers are no longer needed for agricultural use. Moreover, the soil is suitable for use as a soil substitute, for use as a soil supplement, for greening developments, for preventing erosion, for improving regional water supplies, for preventing floods, for preventing climate change, for reducing carbon dioxide content in the atmosphere, for waste water cleaning and treatment, for exhaust air cleaning and building air purification, for creating material flow cycles from biogenic waste and/or waste water in order to develop and utilize land use and development systems.
US08465566B2
A honeycomb body includes at least one housing and metal foils forming a channel structure. The channel structure is fastened to the housing by a multiplicity of linear brazed connections. A production method for providing the linear brazed connections between the channel structure and the housing and an exhaust gas treatment component having the honeycomb body in an exhaust system of a motor vehicle, are also provided.
US08465560B1
A gasoline deposit control additive composition for use in a fuel comprising from about 70 to about 95 volume percent of hydrocarbons in the gasoline boiling range and from about 5 to about 30 volume percent of at least one alcohol, comprising the imine or tertiary amine product of the reaction between (a) at least one aldehyde or ketone or mixture thereof having the formula R16 CHO, R16 CH2 CHO, R17 (C=0) R18 or R17 CH2 (C=0) R18, wherein R16, R17, and R18 are the same or different and are each independently a straight or branched chain hydrocarbyl or aryl group that contains from 1 to 18 carbon atoms, and (b) a primary or secondary amine functionality.
US08465555B2
The present subject matter includes a method of producing an apparatus for use in a patient, the method including etching an anode foil, anodizing the anode foil, assembling the anode foil, at least one cathode foil and one or more separators into a capacitor stack adapted to deliver from about 5.3 joules per cubic centimeter of capacitor stack volume to about 6.3 joules per cubic centimeter of capacitor stack volume at a voltage of between about 465 volts to about 620 volts, inserting the stack into a capacitor case, inserting the capacitor case into a device housing adapted for implant in a patient, connecting the capacitor to a component and sealing the device housing.
US08465551B1
This invention relates to a temporary indwelling prostatic stent which provides a passage for urine through the prostatic urethra and which enable the patient to void the bladder at will. This temporary prostatic stent consists of a coiled or braided made out of metal or plastic section which spans the prostatic urethra, wings composed of memory alloy allowing an anchoring means in the bladder, and an anchoring means below the external sphincter, and a retrieval string to facilitate removal of the stent from the patient.
US08465538B2
A variable length endovascular prosthesis to prevent endoleaks includes a substantially tubular first graft member having an interior surface, an exterior surface, and an open end, and a substantially tubular second graft member engaged coaxially within the first graft member, the second graft member having a proximal end. The prosthesis further includes a substantially tubular fluid-tight connecting member attached at one end to the first graft member and attached at another end to the second graft member, where the connecting member is axially compressible and expandable to facilitate engagement of the proximal end of the second graft member within the first graft member while maintaining a seal between the proximal end of the second graft member and the open end of the first graft member.
US08465523B2
An apparatus and system useful as a stabilization or correction system for a spinal column. A threaded rod is used that can be straight, rigid, bent or flexible depending on the vertebrae condition to be addressed. The rod may be bent or flexible to achieve varying degrees of lordosis (backward curvature) or kyphosis (forward curvature) before being affixed to the anchoring means and apparatus. The straightness, curvature, bent, or flexibility of rod depends upon the location along the spinal column. Once installed to the vertebrae, the rod provides the proper, desired curvature and stabilization for the spinal column. Sharp edges and corners of the apparatus are eliminated by rounding the edges and corners.
US08465519B2
A tissue puncture closure device includes an anchor, a sealing plug, a suture coupled to the sealing plug, a compaction arrangement, and an automatic driving assembly. The automatic driving assembly includes first and second spool members and an actuation member. The first spool member is configured to coil a portion of the suture. The second spool member is configured to coil a portion of the compaction arrangement. The actuation member is coupled to the first and second spool members. Activation of the actuation member releases the first spool member for rotation to apply a tension force in the suture, and releases the second spool member for rotation to distally advance a portion of the compaction arrangement to compress the sealing plug.
US08465518B2
Methods and apparatus for sealing a puncture or incision formed percutaneously in tissue separating two internal portions of the body of a living being with an anchor, a sealing plug and a filament connecting the anchor and sealing plug are disclosed. The methods and apparatus provide for automatic tamping of the sealing plug. In addition, torque required to tamp the sealing plug is automatically sensed and gear ratios of an automatic tamping device are automatically changed in response to sensed changes in torque. A planetary transmission may be used to automatically change gear ratios in response to the changes in torque.
US08465515B2
Methods and devices are provided for performing surgical procedures using tissue retractors. In general, the methods and devices allow a surgeon to use a retractor to capture a large or small amount of tissue in a fabric and to move the fabric to relocate the tissue to one or more convenient locations during the procedure. The flexible nature of the fabric can allow the fabric to be moveable between an open position, in which the fabric can support tissue, and a closed position, in which the fabric can be folded, rolled, or otherwise compressed in size and fit through a port, such as a trocar or an incision in a tissue wall. Furthermore, the position of the fabric and thus the tissue held in the fabric can be adjusted and readjusted by pushing or pulling one or more grasping elements coupled to the fabric.
US08465496B2
A method for performing a cesarean section includes the occlusion of uterine arteries using an atraumatic occlusion instrument, for example, an atraumatic clamp, after pulling the uterus from the pelvic cavity and placing it on the patient abdomen, The method significantly reduces blood loss in patients. An atraumatic occlusion clamp has disposable covers made of gauze.
US08465494B2
An apparatus (650) for inserting a distal ring (9) of a wound retractor device (2) through a wound opening comprises a bladeless tip (641) for creating the wound opening by forcing tissue apart, and a conveying device (5) for conveying the distal ring (9) through the wound opening. The conveying device (5) comprises a hook element (6) for engaging the distal ring (9) to convey the distal ring (9) through the wound opening, and a receiver housing (651) for receiving a seal (652) and a proximal ring (653) of the wound retractor device (2) to hold the seal (652) and the proximal ring (653) externally of the wound opening, and thus maintain a sleeve portion of the wound retractor device (2) in tension, during conveying of the distal ring (9) through the wound opening.
US08465488B2
An endoscopic surgical instrument includes an insertion section which is inserted into a body cavity, and a surgical section which is disposed on a tip of the insertion section and treats an object. The surgical section includes a body section, and a first electrode, a second electrode, and a third electrode which are disposed on the body section. The surgical section coagulates and cuts the object by using a combination of not less than two of the first electrode, the second electrode, and the third electrode.
US08465484B2
The present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors. The methods rely on non-thermal irreversible electroporation (IRE) to cause cell death in treated tumors. In embodiments, the methods comprise the use of high aspect ratio nanoparticles with or without modified surface chemistry.
US08465478B2
There is provided a system, apparatus and methods for developing laser systems that can create a precise predetermined jigsaw capsulotomy. The systems, apparatus and methods further provide laser systems that can use a single laser as a therapeutic laser and as laser radar and that reduce the patient-to-patient variability and doctor-to-doctor variability associated with hand held apparatus for performing capsulorhexis and capsulotomies. There is further provided a precise predetermined jigsaw shot pattern and shaped capsulotomy that is based at least in part on the shape of an IOL and in particular an accommodating IOL.
US08465474B2
In one embodiment, a force sensing robotic surgical instrument includes a proximal housing linkable with a surgical robot arm, a shaft having a proximal portion and a distal portion, the proximal portion operably coupled to the housing, and a force transducer operably coupled to the distal portion of the shaft, the force transducer having a proximal portion, a distal portion, a plurality of radial ribs, and a strain gauge positioned over each of the plurality of radial ribs, the radial ribs forming a plurality of through passages. The instrument further includes a wrist mechanism coupled to the distal portion of the force transducer, an end effector coupled to the wrist mechanism, and a flush manifold that receives a liquid from the proximal portion of the shaft and directs the liquid along a first subset of through passages of the force transducer toward the distal portion of the force transducer. A plenum at the distal portion of the force transducer collects the liquid from the first subset of through passages and redirects the liquid back toward the proximal portion of the shaft along a second subset of through passages different from the first subset of through passages.
US08465467B2
A dual pump aspiration system having both a vacuum level control loop and a flow rate control loop. The system can be operated either as a vacuum priority system or a flow rate priority system.
US08465463B2
A medicament dispensing device including a substantially rigid carpule body which has a dispensing end and an actuation end opposite the dispensing end. The carpule body is substantially tubular and thus defines a carpule bore. The device further includes a plunger operatively disposed within the carpule bore having a plunger actuator near the actuation end of the carpule body and a plunger tip opposite the plunger actuator. The plunger tip and an orifice at the dispensing end of the carpule bore define a medicament volume which may be loaded with a medicament selected to achieve specific therapeutic goals. The carpule body may also include a wound depth scale. The depth scale is typically associated with the dispensing end of the carpule body. Similarly, the medicament dispensing device may include a dosage scale. Also disclosed are methods of dispensing medicaments.
US08465461B2
Drug delivery devices having non-luer connections and adapters and adaption connectors for providing non-luer connections to drug delivery devices are provided. An exemplary drug delivery device for use with a catheter connection includes a blunt needle component with a non-luer connection and a filter component with a non-luer connection, wherein the non-luer connections of the blunt needle component and filter component are incompatible with standard luer fitting and intravenous route-accessing devices. In one or more embodiments, an adapter having a non-luer connection at one end and a luer connector is provided for use with blunt needle components and filter components wherein one of the blunt needle component and the filter component includes a luer connection and the other of the blunt needle component and the filter component includes a non-luer connection. Methods of delivering liquid medication to a catheter are also provided.
US08465456B2
An intravascular aspirating assembly comprising an elongate guidewire having a proximally facing filter disposed on a distal portion thereof, a single operator exchange aspiration catheter disposed on the guidewire, the aspiration catheter having a proximal end, a distal end and an aspiration lumen extending therebetween, an extension catheter slidably disposed in the aspiration lumen and having a length greater than that of the aspiration catheter.
US08465453B2
Medical devices with surfaces on which viable biologic cells are magnetically attracted and retained are disclosed along with methods of magnetic coating. The medical devices can be located in a carrier liquid containing high concentrations of magnetic cells before or after implantation. The carrier liquid with magnetic cells may be contact with the medical device in vitro or in vivo. In either case, the carrier liquid may have a concentration of magnetic cells that is high enough to facilitate coating of the medical device within an acceptable period of time, e.g., several hours or less. Magnetization of medical devices before, during, and/or after implantation and apparatus for performing the same are disclosed. Degaussing of magnetic medical devices is also disclosed.
US08465446B2
A dialysis system includes at least one pneumatic valve, a pneumatic pump in fluid communication with the pneumatic valve, a pneumatic line communicating with an inlet and an outlet of the pneumatic pump, a flow restrictor placed in the pneumatic line, and a logic implementer. The logic implementer is programmed to operate the pneumatic valve to either (i) communicate the pneumatic outlet with the pneumatic inlet of the pneumatic pump through the flow restrictor and the pneumatic line, or (ii) communicate the outlet of the pneumatic pump with a component of the dialysis system.
US08465441B2
A cannula introducing device comprises an elongate body (10) having a needle (12) projecting from a front end, an operating element (24) for displacement longitudinally of the body (10), a plunger (16) disposed at the front end of the body (10), and a coupling means (18), such as a flexible wire, coupling the operating element (24) and the plunger (16), arranged so that retraction of the operating element (24) serves to advance the plunger (16) over the needle (12) and so advance the cannula (30) which is disposed over the needle.
US08465435B2
The invention relates to a method 10 for determining a beat-to-beat stroke volume 9a and/or a cardiac output 9b based on a measurement 2 of suitable arterial pressure data. At the step 4 a waveform of the arterial pressure pulse is assessed based on data obtained during the measurement of step 2. At step 6 a compliance or impedance in dependence of at least one measurement of arterial pressure data is computed using a non-linear model 7. The non-linear model may comprise an arctangent model. The arctangent model may be differentiated numerically or analytically to obtain the compliance or the impedance of an aortic portion. The thus obtained compliance or impedance may then be substituted into a linear model 8. The linear model 8 may comprise a Windkessel model 8a, or a Waterhammer model 8b or any other suitable linear pulse contour model 8c. As a result, the beat-to-beat stroke volume 9a and/or cardiac output 9b are computed.
US08465425B2
In aspects of the present disclosure, an auto turn on blood glucose monitoring unit including a calibration unit integrated with one or more components of an analyte monitoring system is provided. Also disclosed are methods, systems, devices and kits for providing the same.
US08465422B2
Methods and devices are provided to allow the same component used to access a surgical site to assist in closing the surgical opening in which it was disposed. In one exemplary embodiment a flexible retractor is provided that includes proximal and distal ends and a lumen extending therethrough. A wound closure component is associated with the flexible retractor and is configured to engage tissue adjacent to a surgical incision in which the retractor is disposed and move tissue from one side of the surgical incision toward a second side of the surgical incision to assist in closing the surgical incision. In one embodiment the wound closure component includes strands of suture having hooks disposed on a distal end. In another embodiment the wound closure component includes a ring having hooks disposed around a circumference of the ring. Exemplary methods for closing a surgical opening are also provided.
US08465414B2
A clean and inexpensive medical manipulator device can be provided in which a risk of failure caused by current leakage or disconnection is eliminated and reliability is higher than in a manipulator device using an electrically driven actuator or electric motor. The medical manipulator device includes a stage section 3 that can hold a medical instrument 2; a plurality of actuators 4 each linked at one end to the stage section 3; and a base section 5 linked to the other end of each of the plurality of actuators 4 and serving as a base for the plurality of actuators 4, wherein each of the actuators 4 causes the medical instrument 2 and the stage section 3 to displace with respect to the base section 5 by extending or contracting in the longitudinal direction of the actuator 4 in response to a pressure of a liquid 6.
US08465405B2
A solid-bowl centrifuge that includes a drum rotatable about a horizontal axis of rotation and a screw arranged in the drum. Also included are a continuous solids discharge located at a first end of the drum and a continuous liquid discharge located at a second, opposite end of the drum. Further included is at least one discontinuously acting outlet opening including a closure device.
US08465398B2
An elliptical exercise apparatus includes a frame unit having a base frame and an upstanding frame, two crank arms, and an adjustment unit including a motor, a slide mounted movably on the upstanding frame, and a threaded rod connected threadedly to the slide and connected drivenly to the motor. Two swing units are disposed respectively on left and right sides of the frame unit and each includes a handle movable along with the slide, a link rod connected pivotally between an intermediate portion of the handle and one of the crank arms, a pivot arm connected pivotally to the link rod, and a pedal rod connected pivotally between a lower connecting portion of the handle and the pivot arm. The slide moves upwardly or downwardly along the upstanding frame when the motor is activated to adjust the position of the handle relative to the upstanding frame.
US08465397B2
A method is disclosed for guiding a person to a physiological cumulative state in physical exercise, in which the exercise has a physiological target in the form of a physiological state at the end of the exercise, a duration, and a performance parameter. At the start of the exercise the physiological target is set, as is the value of the performance parameter, and during the exercise at regular intervals: at least one quantity proportional to the momentary intensity is measured. The present physiological state and an estimate of the physiological state at the end of the exercise are calculated with the aid of momentary intensity and the exercise performed. A guidance range for the momentary intensity is defined, in order to reach the target state and the performance parameter. The user is guided by feedback to remain within the guidance intensity range.
US08465396B2
A manual valve disconnects a line pressure oil passage and an R position pressure oil passage when a selector is in a D position or an N position and causes the R position pressure oil passage and the line pressure oil passage to communicate when the selector is in an R position. A switching valve is switched to disconnect a low & reverse brake pressure oil passage and the R position pressure oil passage when the selector is in the D position or the N position and a vehicle is driving at a vehicle speed equal to or lower than a predetermined vehicle speed.
US08465393B2
A method of accelerating decoupling of the starting clutch (5) that is able to connect the electric machine (2) to the transmission input in a hybrid drive-train of a motor vehicle, when a decoupling command is issued, at the same time as the regulation of the starting clutch begins for the purpose of decoupling the starting clutch (5) or a specified time after the regulation of the starting clutch begins. The electric machine is regulated in such manner that a torque is built up such that the transition to sliding friction, and thus decoupling and the onset of slip, are sped up while maintaining the nominal driving torque.
US08465382B2
An Electronic Basketball Shooting Coach device is used to recondition the mind helping people maintain the proper elbow angle range when shooting a basketball. The self-contained device is worn on either arm below the elbow of a user. The ergonomically designed device is contained in the specially designed pocket of the sleeve before it can be attached below the elbow. The sleeve wraps around the upper-arm below the elbow and is held in place by hook-and-loop materials. The device has no internal movable parts. The device will articulate a phrase when the programmed non-adjustable trip point range. The device has a sleep mode to save on the common single cell's power and is reactivated by movement. The non-adjustable knob must be positioned up towards the fingers and aligned with the thumb or little finger. Two single cell sources must be added to energize the invention.
US08465379B2
A face portion of a golf club head includes first to fourth main ribs on an inner surface of the head. The first main rib extends from a center portion of the face portion toward a crown, and the second main rib extends from the center portion toward a sole. The face portion is formed to have such a thickness that the center portion, the first main rib, and the second main rib become thinner in this order. The third and fourth main ribs extend from the center portion in outward directions of the face portion.
US08465372B2
The torque fluctuation absorber includes a flywheel fixed on a first rotating shaft by a fixation member, a damper unit connected with a second rotating shaft and absorbs fluctuation of torque occurred between the first rotating shaft and the second rotating shaft by elastic force, and a limiter unit provided on a power transmission path between the flywheel and the damper unit and inducing a slide when the fluctuation of the torque exceeded a predetermined value. A predetermined member rotates with the first rotating shaft on a power transmission path between the first rotating shaft and the limiter unit. The predetermined member has a side plate at the damper unit and a guide portion that prevents movement radially of a hub member, and the guide portion is provided at radially internal side of the fixation member.
US08465368B2
The field of the invention relates generally to sports and event betting, and more specifically to the use of the Internet in land-based casino sports and event betting. A bettor signs onto an Internet website to find what bets are being accepted and the bettor then places and registers a bet. The player then goes and places pays for the bet at a land-based casino prior to the start of the event. Further, follow-up rounds of making a wager may then be performed over a network such as, for example, the Internet.
US08465367B2
Methods, systems, and computer programs for playing browser based game with alternative controls and interfaces are presented. One method includes an operation for receiving a definition of native inputs defined for causing actions in the game. The native inputs are tied to game actions through a native device. When a gesture recognition system, lacking some capability to play the game, is detected, at least some of the actions in the game associated with the native inputs are mapped to gesture inputs detected by the gesture recognition system. This enables game play with the gesture recognition system. Further, the alternate gesture inputs are translated to corresponding actions in the game according to the mapping during game play.
US08465366B2
Described are methods, systems, and apparatuses, including computer program products, for biasing a musical performance input of a player of a rhythm-action game to a part in the game. In one aspect this is accomplished by providing, by a game platform, a history of a degree of matching between a prior music performance input data and a prior music data associated with a first part in a musical composition. Then, on a display, a plurality of target music data, each associated with a respective part in the musical composition, is displayed, with one of the plurality being associated with the first part. Music performance input data is received by the game platform via an input device, such as a microphone, and, based on the history, the received music performance input is assigned to the target music data of the plurality that is associated with the first part.
US08465364B2
Systems and methods for playing live casino games. The systems have a casino table with changeable displays for players and a common or central display. The displays portray virtual playing cards or symbols to live participants. Shuffling, cutting, dealing, betting and return of playing cards are accomplished using data processing functions within an electronic game processor or processors which enable these functions to be performed quickly and without manual manipulation of playing cards. The invention allows casinos to speed play and reduce the risk of cheating while maintaining the attractive ambiance of a live table game. The systems can also be multi-user slot machines using the processor to associate or assign one or more symbols either with the virtual playing cards or as slot symbols in participant subsets. The participant subsets are compared to a predetermined list so that payoffs can be awarded on the basis of winning symbols or combinations of symbols.
US08465360B2
In a shooting game device capable of having more than one player play a game, stop control module (M1), generates first stop information (ST1) upon detecting that a first gun unit (30) points out of the screen, and generates second stop information (ST2) upon detecting that a first gun unit (40) points out of the screen. A virtual view position movement module (M2) moves a first virtual view position for a first player and a second virtual view position for a second player at the predetermined speed, but stops the movement of the first virtual view position upon detecting first stop information (ST1) and stops the movement of the second virtual view position upon detecting second stop information (ST2). An image generation module (M4) generates a first image (GD1) for the first player and a second image (GD2) for the second player in a virtual space based on first position information (PS1) showing the first virtual view position and second position information (PS2) showing the second virtual view position.
US08465357B2
A gaming machine including a display. The display includes a plurality of display positions for displaying combinations of symbols. A controller controls operation of the machine. The controller includes a processor for processing data and displaying selected data on the display. A selector is operable by the player of the machine for enabling the player to select at least one feature which can be added to a base game played on the machine.
US08465355B1
A method and apparatus is provided for conducting a word game that is intended to be played by a plurality of participants though not necessarily at the same time or from the same location. The game may be played using one or a plurality of electronic client devices. One or more participants are assigned one or more words or phrases and tasked to create a work that includes text that should contain a predetermined number of the assigned words or phrases. Such work may also include other assigned materials such as images, moving images, other visual objects, audio pieces, other text or instructions. The participant(s) submit the work to a contest to be judged by other participants and also participate in judging contests containing the works of other participants.
US08465344B2
A method of producing a grinding wheel is provided. An outer profile of an outer surface of the grinding wheel is formed with a rotary dresser element, so that the outer profile corresponds to a dressing profile of the rotary dresser element. An inner profile of an inner surface of the grinding wheel is formed with the rotary dresser element, so that the inner surface corresponds to the dressing profile of the rotary dresser element.
US08465342B2
A polishing system includes a polishing pad with an aperture that extends through all layers of the polishing pad and a light transmissive film positioned on top of a light-generating or light-guiding element of an optical monitoring system.
US08465332B2
An electrical contact assembly is provided. The assembly includes a contact hood having a body including an axis and an opening extending through the body along the axis. The opening has an inner surface. The contact hood is configured to be received in an opening of a connector housing. At least two protrusions are formed on the inner surface of the contact hood opening. An electrical contact is provided having a body including a contact end and a socket end. The socket end is inserted axially into the opening of the contact hood. The contact end of the electrical contact is configured to extend from a mating end of the connector housing. At least two apertures are formed on the socket end of the electrical contact. The at least two protrusions are received in the at least two apertures to secure the electrical contact within the contact hood.