US11802424B2
A motor vehicle door lock comprising a locking mechanism that essentially consists of a rotary latch and a pawl. In addition, a lock retainer interacting with the locking mechanism is produced, which is introduced into the locking mechanism in order to achieve the closed position and rests on a load arm of the rotary latch in the closed position of the locking mechanism. According to the invention, the load arm is provided with a force deflection contour for the lock retainer. The force deflection contour changes a force direction acting on the load arm from the lock retainer, at least in the event of an excessive impact of the lock retainer.
US11802423B2
A door lock contains: a casing, a head, a first clutch element, a second clutch, a drive gear, a gear assembly, a guide rod, a locking column, and a holder. The casing includes a first connection part and a second connection part. The head includes a retainer, a first engagement portion, and a receiving orifice. The first clutch element includes a groove. The second clutch element includes a driving orifice, a limitation protrusion, and an abutting segment. The drive gear includes a defining trench. The gear assembly includes a driven gear, a motor, a transmission gear, a first meshing gear, and a second meshing gear. The guide rod includes a toothed section, a guiding stem, a tongue, and a resilient element. The locking column includes a cross section in a square shape. The holder includes an extending sheet, a fixing orifice, a fitting sleeve, and a first through orifice.
US11802421B2
An electronic lockbox includes a latching apparatus that uses a rotary actuator with multiple positions to achieve multiple locking states. Multiple positions of the actuator are detected, using optical sensors. The locking mechanism includes an outer sleeve and an inner cylindrical barrel that are coupled with torsion springs. The lockbox has a shackle and a key bin that include latch pins which are retained by the inner barrel when in the locked state, and the barrel can be rotated to either release the shackle or to release the key bin that typically holds a building's key. During insertion of a latch pin into the rotatable barrel, a first interior protrusion is sufficiently wide such that after the first latch pin has been inserted into the barrel and has become latched, the first latch pin does not unlatch itself as the second latch pin is inserted and rotates the rotatable barrel during the second latch pin insertion.
US11802420B2
A stringer for an off-set board-on-board fence having an inverted U-section elongated body having two mutually opposed sides depending from an intermediate adjoining portion having laterally off-set and longitudinally over-lapping first and second sets of spaced board slots extending flush with inside surfaces of the opposed sides for attaching fence boards of predetermined cross-section flush to the inside surfaces of the opposed sides of the stringer. The stringer has board fastening apertures in the opposed sides of the stringer to fasten the fence boards flush with the inside surfaces of the opposed sides. The stringer has a plurality of bracket attachment apertures, preferably square, arranged longitudinally from end to end, between the first and second sets of board slots for attaching post brackets at each end of the stringer. A stringer support of each opposing bracket is within range of one bracket attachment aperture at each end of the stringer.
US11802409B2
A hardware system for use on a deck railing includes two pair of flat shear struts, one pair on each the lower and upper main rail each extending up to the length of each main rail between the deck posts. Both the upper and lower main rail shear strut pairs are identical and a mirror image of one another. The hardware system further includes an infill embodiment that includes a sub-rail that houses one of the shear struts in each pair, is attached to the sub-rail which is further attached to the balusters between the upper sub-rail and the lower sub-rail. The second shear strut in each pair is attached to the underside of the main upper rail and on top of the main lower rail. When the infill embodiment is placed into the deck railing frame opening, screws hold the railing infill in place creating a removable deck railing.
US11802406B2
A hardscaping unit includes a first block fixedly attached to a second block. The method of assembling the hardscaping unit includes the steps of forming a first block from a first material, placing a second material into a mold, contacting a surface of the first block with the second material that is in the mold, maintaining contact of the surface of the first block with the second material while transitioning the second material from a first state to a second state, the second state being more solid than the first state, and when in the second state the second material forms a second block that is fixedly attached to the first block.
US11802395B2
A system, a method, and an apparatus for a temperature-adjusting adapter is described. The adapter includes first and second connectors coupled to first and second supply lines, wherein each of the first and second connector comprise an input, an output, and an adjustment port; a tube and an adjustment mechanism positioned between the adjustment ports of the first and second connectors, wherein the adjustment mechanism is movable between an open position and a closed position for selecting a temperature of a third fluid exiting the output port of the first or the second connector, wherein the third fluid is one of the first fluid, the second fluid, or a mixture of the first fluid and the second fluid, and wherein a mixing ratio of the mixture is based at least in part on the position of the adjustment mechanism.
US11802389B2
The present invention discloses an ecological seawall water close side embankment slope drainage structure and a construction method thereof. The ecological seawall water close side embankment slope drainage structure includes a seawall, and further includes a wave dissipation ridge and water collecting wells, wherein the wave dissipation ridge is disposed at an upper side of the seawall, a drainage blind ditch is formed in an upper surface of the seawall, and the drainage blind ditch is matched with the wave dissipation ridge; the water collecting wells are distributed at a lower side of the drainage blind ditch at equal intervals, and lower end portions of the water collecting wells communicate with drainage concealed pipes; and pipe seats are disposed at a lower end portion of an inclined plane of the seawall, lower end portions of the drainage concealed pipes are fixedly connected onto the pipe seats, and flap valves are rotationally connected to lower end surfaces of the drainage concealed pipes. The present invention not only can reduce the erosion degree of sea waves to the seawall, but also can collect seawater going over the wave dissipation ridge and discharge the collected seawater into the sea again.
US11802387B2
A vacuum and container assembly is provided for collecting and disposing of dog poop. The vacuum includes a housing with an inlet tube or nozzle. The container assembly includes an outer sleeve and an inner flexible, air permeable bag. The sleeve is open at the rear end so as to fit over the vacuum nozzle, with the bag residing in the nozzle. The front end of the container assembly is temporary closed by flexible fingers. When the vacuum is turned on, the dog poop is suctioned past the fingers into the bag, without touching the vacuum housing or nozzle. The container assembly can then be removed from the nozzle and deposited in a waste receptacle for disposal.
US11802380B2
A track maintenance machine for carrying out track position corrections includes a machine frame movable by on-track undercarriages on rails of a track and a track position measuring system having two outer measuring devices and a central measuring device with a common reference base, relative to a longitudinal direction of the machine. The measuring devices are defined in their position relative to the rails. Two mutually aligned measuring chords are tensioned or stretched as a reference base between the outer measuring devices. The central measuring device includes a measuring transducer for detecting position data of the two measuring chords. The position data are fed to an evaluation device in order to determine a longitudinal level for each rail and a versine. Thus, two measuring chords are sufficient to detect all of the track parameters. A method for operation of a track maintenance machine is also provided.
US11802376B2
The present invention relates to a polymer composition comprising an anionic polymer composite having a synthesized polymer portion and a polysaccharide portion, obtainable by polymerizing vinyl monomers in the presence of the polysaccharide. The present invention further relates to a strength system and methods of production and use in providing a paper product.
US11802372B2
The invention relates to a rope made of textile fiber material, comprising a rope core and a sheath surrounding the rope core, wherein the sheath, an intermediate sheath located between the sheath and the rope core and/or a reinforcement located between the sheath and the rope core comprise(s) a twine of excess length, the twine of excess length being formed in that it comprises at least a first yarn and a second yarn which are twisted together, the first yarn having a greater length than the second yarn, measured in an untwisted state of a unit length of the twine. In a further aspect, the invention relates to a method of manufacturing a twine of excess length for the above-mentioned rope.
US11802359B2
Backing fabric shifting relative to needles and gauge parts for seizing yarns is utilized in a tufting machine having needle plate fingers or backing support that reciprocates in synchronization with the cycles of the needles to support the backing during penetration of the backing fabric while allowing backing shifts between stitches.
US11802358B2
Nonwoven fabrics suitable for a wide variety of applications (e.g., healthcare, filtration, industrial, packaging, etc.) are provided. In one aspect, the nonwoven fabric includes a plurality of segmented fibers. Each of the plurality of segmented fibers may comprise a fiber axis and a plurality of alternating larger diameter and smaller diameter segments along the fiber axis. The plurality of segmented fibers may be substantially aligned in a first direction.
US11802355B2
Disclosed is a weaving method with which the yarn tension of several part groups with at least one warp thread per part group is controlled or adjusted separately, in order to follow a respective reference yarn tension profile during weaving, where, for at least one part group, the reference yarn tension profile is changed during weaving, where the reference yarn tension profile is determined and changed separately for at least two part groups, and where each reference yarn tension profile is selected from a collection of different reference yarn tension profiles. Also disclosed is a weaving machine provided with yarn tensioning elements, a storage unit in which said collection is provided, and a control or steering unit in order, in cooperation with the yarn tensioning elements, to adjust or control the yarn tension in separate warp threads using the indicated weaving method.
US11802351B2
The present application discloses and claims a method to make a flexible ceramic fibers (Flexiramics™) and polymer composites. The resulting composite has an improved mechanical strength (tensile) when compared with the Flexiramics™ respective the nanofibers alone. Additionally a composite has better properties than the polymer alone such as lower fire retardancy, higher thermal conductivity and lower thermal expansion. Several different polymers can be used, both thermosets and thermoplastics. Flexiramics™ has unique physical characteristic and the composite materials can be used for numerous industrial and laboratory applications.
US11802348B2
An element body has an exposed surface including a selective surface material which is to be coated with the coating material and a non-selected surface material which is not to be coated with the coating material. The selected surface material has different material properties than the non-selected surface material. The element body is coated with the coating material by applying a surface modifier only on the surface of the selected surface material and thereafter coating the surface of the selected surface material to which the surface modifier has been applied with the coating material.
US11802347B2
A molded article includes a first plateable region spaced apart from a second plateable region the first plateable region by a barrier of electrically insulating material. Each of the plateable regions include an associated plateable layer of electrically conductive material for being electroplated with a different plateable finish. Several different geometries and configurations of the barrier and/or the plateable regions are provided to prevent migration of plating material from one of the plateable regions acting as bipolar electrode while another one of the plateable regions is being electroplated. A non-plateable insert may be disposed between the plateable regions to prevent migration of plating material from one of the plateable regions onto the other one of the plateable regions. A conducive robber in electrical communication with one of the one of the plateable regions, and which may be removable, may also be used to prevent migration of plating material.
US11802344B2
A hydrogen production system includes: a hydrogen production device connected to an electric power system or connected to a power generation device using renewable energy and configured to produce hydrogen by electrolyzing pure water; an output control unit capable of controlling an amount of power supplied from the electric power system to the hydrogen production device according to request from the electric power system; a first pure water line for supplying pure water to the hydrogen production device; a first adjustment device capable of adjusting an amount of pure water supplied to the hydrogen production device via the first pure water line; and a first control unit configured to control the first adjustment device, based on a power amount signal indicating information on an amount of power supplied from the electric power system to the hydrogen production device.
US11802337B1
Methods for generating one or more atmospheric pressure plasma jets that can be used to deposit various types of conductive traces, coatings, and micro/nano-sized particles/structures on two or three dimensional body surfaces. The method includes generating atmospheric pressure plasma, nebulizing a precursor to generate an aerosol; receiving the aerosol from the nebulizer in a chamber; mixing the atmospheric pressure plasma with the aerosol from the chamber at a nozzle; and printing the plasma-exposed aerosol onto the surface of a substrate.
US11802336B2
The present disclosure relates to an apparatus for fluidised-bed chemical vapour deposition from a gaseous phase allowing the temperature of the fluidised bed to be stabilised during the deposition and also to an associated method for its implementation, the apparatus being characterised in that it comprises a porous thermal insulator present in an inlet zone and configured to be passed through by the gaseous phase, said porous thermal insulator having an effective thermal conductivity at 20° C. less than or equal to 3.5 W·m-1·K-1.
US11802315B2
The present invention relates to a method for determining or predicting the response of a patient diagnosed with non-small-cell lung carcinoma to targeted pharmacotherapy. The present invention also aims to provide methods and devices for predicting the response of patients diagnosed with non-small-cell lung carcinoma to specific medicaments. More specifically, the present invention provides methods which measure kinase-activity by studying phosphorylation levels and profiles and inhibitions thereof by drugs in blood samples of said patients.
US11802304B2
Providing herein, among other things, are kits, compositions and methods that relate to DNA fragmentation. An embodiment of a composition provides combining: one or more enzymes capable of nick translating activity, a dNTP mix comprising at least one dNTP having a modified base, and at least one modification-sensitive nicking endonuclease that is prevented from nicking DNA if its recognition site contains the modified base. When the composition is added to a sample comprising a double-stranded DNA template that comprises recognition sites for the modification-sensitive nicking endonuclease, a reaction mix was produced which could be incubated for any time period in excess of about 5 minutes to produce fragments of a desired size of the double-stranded DNA template. In this method, the fragments produced include the modified base and, as such, are not re-nicked by the nicking endonuclease.
US11802302B2
The invention provides methods and reagents for detecting luciferase in biological samples. The methods and reagents of the present invention allow detecting fungal luciferase or a functional analog thereof.
US11802301B2
This disclosure concerns production of product peptides with a target amino acid sequence by proteolysis of a recombinant polypeptide comprising specific protease recognition sites or chemical cleavage sequences. In some embodiments, the product peptide is released from repeating peptide units in the recombinant polypeptide by removal of intervening amino acid sequences by proteolysis by proteases that recognize sites within the intervening amino acid sequences and a carboxypeptidase, aminopeptidase, and/or further protease.
US11802298B2
The present invention provides a decanedioic acid produced by microbial fermentation process, in which the content of C10 aliphatic acid and C10 hydroxy aliphatic acid is maintained at a very low level. The present invention also provides a preparation method of the decanedioic acid and a polymer prepared by using the decanedioic acid as monomer. The decanedioic acid provided by the present invention is prepared by microbial fermentation process. The decanedioic acid product which is produced through the processes of microbial fermentation and separation has a higher purity, a higher thermal stability, and a lower impurity content. The decanedioic acid provided by the present invention could satisfy the requirements of high grade product of polyamide or polyester to produce polymer with excellent qualities. The preparation method of the decanedioic acid provided by the present invention which has many advantages of mild reaction conditions, environmental friendliness, high yield, and good product quality, may replace the chemical method to be used in industrial scale production of the decanedioic acid.
US11802295B2
Provided are methods, systems, and kits for cell processing, e.g., for therapeutic use, such as for adoptive cell therapy. The provided methods include transduction methods, in which cells and virus are incubated under conditions that result in transduction of the cells with a viral vector. The incubation in some embodiments is carried out in an internal cavity of a generally rigid centrifugal chamber, such as a cylindrical chamber made of hard plastic, the cavity of which may have a variable volume. The methods include other processing steps, including those carried out in such a chamber, including washing, selection, isolation, culture, and formulation. In particular, the disclosure relates to method providing advantages over available processing methods, such as available methods for large-scale processing. Such advantages include, for example, reduced cost, streamlining, increased efficacy, increased safety, and increased reproducibility among different subjects and conditions.
US11802292B2
The disclosure relates to modified orthopoxvirus vectors, as well as methods of using the same for the treatment of various cancers. The disclosure provides modified orthopoxvirus vectors that exhibit various beneficial therapeutic activities, including enhanced oncolytic activity, spread of infection, immune evasion, tumor persistence, capacity for incorporation of exogenous DNA sequences and safety. The viruses we have discovered are also amenable to large scale manufacturing protocols.
US11802288B1
The disclosure relates to improvements in methods for efficient editing of two or more endogenous soybean genes by insertion of one or more single stranded DNA donor molecules that are not homologous to the insertion sites in the soybean genome.
US11802287B2
Described are methods and materials for the genetic modification of plants by specific gene targeting and precise editing of nucleic acid sequences in a plant. The methods and materials provided herein enable one to edit the plant genome by design to control the expression of endogenous genes and/or control the transmission and expression of transgenic traits. Provided are also methods of producing plants having a desirable agronomic trait by crossing a transgenic plant expressing a gRNA with a plant expressing a Cas enzyme, and selecting a progeny plant having the desirable agronomic trait or a seed thereof.
US11802284B2
An object of the present invention is to reveal a role of a stem cell control factor including Matrin-3 in cancer exhibiting neural differentiation including small cell lung cancer, and develop a medicine useful for treating cancer and the like based on the role. Among cancers having the cancer stem cell controlling mechanism, in cancer exhibiting the differentiation potency, the peculiar balance where both of expression of a stem cell maintenance factor and expression of a differentiation promoting factor are higher as compared with normal cells is retained. Additionally, in undifferentiated cancer, the peculiar balance where expression of a stem cell maintenance factor is higher as compared with normal cells is retained. In cancer in which the cancer stem cell controlling mechanism exists, these peculiar balances of a stem cell control factor different from the balance of normal cells exist. In the medicine for treating cancer and the method for treating cancer of the present invention, proliferativeness of cancer is suppressed by breaking down this balance of a stem cell control factor.
US11802274B2
The present application provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.
US11802271B2
The present invention relates to a method for irradiating a population of mammalian cells comprising at least one target mammalian cell with electron beams and/or X-rays, characterized in that: (i) a composition comprising a population of mammalian cells is irradiated in vitro with electron beams and/or X-rays, the population of mammalian cells containing at least one target mammalian cell and the dose rate being within the range from 5 Gy/sec to 107 Gy/sec, and (ii) optionally viable target mammalian cells are isolated or enriched from the population of mammalian cells, and to agents obtainable thereby and to uses thereof.
US11802264B2
Apparatuses and methods are described for the use of optically driven bubble, convective and displacing fluidic flow to provide motive force in microfluidic devices. Alternative motive modalities are useful to selectively dislodge and displace micro-objects, including biological cells, from a variety of locations within the enclosure of a microfluidic device.
US11802261B2
A system and method are provided to produce a beverage concentrate such as a beer extract. A forward osmosis (FO) filtration technique removes pure water from a conventional brewed beer; accordingly, the beer extract can be produced without distillation or other alteration steps that may negatively impact of flavor and aroma components of the beer. A draw solution is used to provide a differential osmotic pressure through a FO filtration device. The diluted draw solution is recycled by reverse osmosis, distillation, and combinations thereof.
US11802258B2
A fragrance precursor represented by formula (1): wherein R1 represents a hydrogen atom, an alkyl group having a carbon number of 1 to 12, a hydroxy group, a methoxy group or an ethoxy group R2 represents a single bond, an alkylene group having a carbon number of 1 to 2, which may have a substituent, or a vinylene group which may have a substituent; and R3 represents a residue resulting from removal of one hydrogen atom of a hydroxy group from a fragrance alcohol having a carbon number of 5 to 20 or a phenol which may have a substituent.
US11802254B2
A grease composition may be used for speed reducers and speed increasers, being excellent in both torque transmission efficiency and leak prevention performance. The grease composition may contain a base oil (A) and a urea-based thickener (B), which is used for speed reducers and speed increasers, wherein the particles containing the urea-based thickener (B) in the grease composition satisfy the following requirement (I). Requirement (I): the area-based arithmetic average particle diameter of the particles is 2.0 μm or less, as measured by a laser diffraction/scattering method.
US11802252B2
Fuel composition rich in aromatic compounds, paraffins and ethers, and use thereof in motor vehicles
The object of the present invention is a fuel composition comprising: (i) from 50 to 79% by mass of a mixture of hydrocarbons comprising: a) from 35 to 55% by mass of aromatic compounds; b) from 30 to 50% by mass of non-cyclic paraffins containing at least 5 carbon atoms; and c) from 5 to 15% by mass of naphthenes; (ii) from 20 to 40% by mass of one or more ethers; and (iii) from 1 to 10% by mass of butane. This composition is useful for supplying a controlled-ignition engine, in automobile vehicles intended for general-public applications or for competition.
US11802239B2
Provided are a quantum dot, a method of preparing the quantum dot, an optical member including the quantum dot, and an electronic device including the quantum dot. The quantum dot includes a core including indium (In), A1, and A2; and a shell covering the core. A1 is a Group V element, A2 is a Group III element other than indium, and the core includes a first region, and a second region covering the first region. The first region does not include A2, and includes indium and A1, and the second region includes indium, A1, and A2, and indium and A2 are alloyed with each other in the second region.
US11802237B2
The present invention provides a method for producing a powder containing zirconia particles and a fluorescent agent that enables easy production of a zirconia sintered body having both high translucency and high strength despite containing a fluorescent agent. The present invention relates to a method for producing a zirconia particle- and fluorescent agent-containing powder, comprising: a mixing step of mixing a zirconia particle-containing slurry and a liquid-state fluorescent agent; and a drying step of drying the slurry containing the zirconia particles and the fluorescent agent. Preferably, the fluorescent agent comprises a metallic element, and the powder comprises the fluorescent agent in an amount of 0.001 to 1 mass % in terms of an oxide of the metallic element relative to a mass of zirconia. Preferably, the zirconia particles have an average primary particle diameter of 30 nm or less. Preferably, the zirconia particles comprises 2.0 to 9.0 mol % yttria.
US11802232B2
A polymer-nanofiller hydrogel including polymer hydrogel and nanofiller. The nanofiller is or includes nanosand. A method for forming the polymer-nanofiller hydrogel. A method of treating a wellbore in a subterranean formation, including applying a polymer-nanofiller hydrogel to the wellbore.
US11802230B2
The present application pertains to liquid-liquid phase transition compositions and processes. In one embodiment a liquid-liquid phase transition process comprises first forming a composition comprising a glycol polymer and water and then phase transitioning the composition at or above the composition's cloud point temperature to form at least two liquid phases. The enthalpy of liquid-liquid phase transition may be greater than 5 kJ per kg as measured by a calorimeter and each liquid phase may have unique and advantageous properties. In another embodiment the application pertains to compositions suitable for liquid-liquid phase transition compositions.
US11802225B2
A method for manufacturing a polylactic acid-based hot melt adhesive includes: (1) preparing a first polylactic acid composition by adding a phosphite and a hindered phenol to a mixture prepared by adding and melt-mixing a first polylactic acid (relative viscosity 2.5-4.0) in a liquid mixture of a dithiocarbamate and a plasticizer at 180 to 280° C., wherein with respect to 100 parts by weight of the first polylactic acid, 10 to 100 parts by weight of the plasticizer, 0.02 to 0.3 parts by weight of the dithiocarbamate, 1 to 10 parts by weight of the phosphite, and 1 to 10 parts by weight of the hindered phenol are used; and (2) mixing a second polylactic acid (relative viscosity 2.5-4.0), into the first polylactic acid composition at 180-280° C., a weight ratio of the first polylactic acid/the second polylactic acid is 2/8 to 8/2.
US11802224B2
The present invention aims to provide an adhesive tape that is easily peelable while capable of maintaining high adhesion at high temperature. The present invention also aims to provide a method for fixing an electronic device component or an in-vehicle device component using the adhesive tape and a method for producing an electronic device or an in-vehicle device. Provided is an adhesive tape including an adhesive layer containing: an acrylic copolymer; and 0.01 parts by weight or more and 10 parts by weight or less of a compound having a structure represented by the following formula (A) or (B) relative to 100 parts by weight of the acrylic copolymer:
US11802200B2
The invention provides systems and methods for substantially improving the compaction resistance of isoporous block copolymer (BCP) film by adding a high molecular weight hydrophilic additive in the casting dope formulation. Systems and methods disclosed also disclose several other multifunctional enhancements to film properties including: low fouling propensity, improved permeability, improved permeability retention upon drying, and ability to tune the substructure and pore size of these novel BCP films. These porous BCP films are useful in filtration and separations applications and are amenable to standard manufacturing practices.
US11802199B2
There is provided a thermoplastic fluororesin tube that, during the production of a catheter, can prevent a gap or air bubbles from being formed in the connection part of the catheter, and can be suitably used for the production of a catheter. A thermoplastic fluororesin tube, the thermoplastic fluororesin tube having tearability in a longitudinal direction, wherein a thermal expansion coefficient in the longitudinal direction upon heating in a gaseous phase at a temperature of 100° C. for 5 minutes is 0% or more.
US11802198B2
A fluororesin composition is provided. The fluororesin composition comprises the following constituents: (A) a first fluororesin, which is polytetrafluoroethylene (PTFE) resin; (B) a first filler, which is a flat glass fiber; and (C) particles of a second fluororesin, which are coated with polysiloxane, wherein, the particle size of the polysiloxane-coated particles of second fluororesin ranges from 0.2 μm to 80 μm, and the melting point of the second fluororesin is lower than the melting point of the first fluororesin.
US11802177B2
An imide oligomer is provided for use in a cured product that has a high glass transition temperature after curing and is excellent in thermal decomposition resistance, adhesiveness, and long-term heat resistance. Also provided are a curable resin composition and an imide oligomer composition each containing the imide oligomer, an adhesive containing the curable resin composition, and a curing agent containing the imide oligomer composition.
US11802162B2
Provided herein are antibodies, or antigen binding portions thereof, that bind to glucocorticoid-inducible TNF receptor (GITR). Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.
US11802160B2
The present disclosure provides antibody sequences found in antibodies that bind to human CD25. In particular, the present disclosure provides sequences of anti-human CD25 antibodies, which do not block the binding of CD25 to IL-2 or IL-2 signalling. Antibodies and antigen-binding portions thereof including such sequences can be used in pharmaceutical composition and methods of treatment, in particular for treating cancer.
US11802156B2
The present disclosure relates to antibodies including human antibodies and antigen-binding portions thereof that specifically bind to MAdCAM, preferably human MAdCAM and that function to inhibit MAdCAM. The disclosure also relates to human anti-MAdCAM antibodies and antigen-binding portions thereof. The disclosure also relates to antibodies that are chimeric, bispecific, derivatized, single chain antibodies or portions of fusion proteins. The disclosure also relates to isolated heavy and light chain immunoglobulins derived from human anti-MAdCAM antibodies and nucleic acid molecules encoding such immunoglobulins. The present disclosure also relates to methods of making human anti-MAdCAM antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions for diagnosis and treatment. The disclosure also provides gene therapy methods using nucleic acid molecules encoding the heavy and/or light immunoglobulin molecules that comprise the human anti-MAdCAM antibodies. The disclosure also relates to transgenic animals or plants comprising nucleic acid molecules of the disclosure.
US11802154B2
Provided herein are antibodies, or antigen binding portions thereof, that bind to CD200. Also provided are uses of these proteins in therapeutic applications, such as the treatment of cancer and in conjunction with organ transplantation. Also provided are nucleic acids encoding the heavy and/or light chain variable regions (or heavy and/or light chains) of the antibodies, vectors comprising the nucleic acids, and cells that produce the antibodies.
US11802150B2
Provided herein are interleukin 7 (IL-7) binding proteins, pharmaceutical compositions and their use in the treatment or prevention of a disease or condition.
US11802140B2
A system, including methods and compositions, for treatment of ischemia.
US11802137B2
A method for preparing an intermediate by a reduced glutathione-indicated amino acid Maillard reaction is provided. The method includes a two-stage reaction at an increased temperature. A reduced glutathione is added after different times of a low-temperature reaction, and a subsequent Maillard reaction is effectively inhibited on a basis wherein a substance is interacted with an intermediate degradation product to reduce a formation of colored substances. Comparing with a browning of Maillard products after a high-temperature stage, a reaction time with a best color inhibition effect is found to be the optimal preparation condition of the intermediate, and the intermediate is prepared in an aqueous medium at a low temperature under this optimal preparation condition. The method uses the water soluble reduced glutathione as a tracer to improve a tracing accuracy comparing to cysteine.
US11802133B2
The invention provides new heterocyclic compounds having the general formula (I) wherein A, L, X, m, n, R1 and R2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
US11802130B1
The benzofuro[3,2-c]-chromen-6-one compounds are antibacterial agents. The emergence of drug-resistant bacteria calls for constant development of new antibacterial agents with the aim of generating medicaments that are potent against drug sensitive and resistant bacteria and are well tolerated. The present compounds are not only new, but have very valuable antimicrobial properties. These compounds showed a broad spectrum of activity against gram-positive and gram-negative bacteria, as well tuberculosis mycobacteria. They also showed potent activity against drug-resistant bacteria, such as MRSA and VRSA. The molecular target of these compounds was identified as DNA Gyrase B. Based on their pharmacological profiles, the present compounds may find important clinical applications for severe infectious diseases and tuberculosis.
US11802112B2
The present invention relates to preparation of pyrazoles. This invention further relates to a continuous flow micro-total process system for preparation of celecoxib, a COX-2 selective non-steroidal anti-inflammatory drug, and analogs thereof.
US11802105B2
The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
US11802102B2
The present disclosure provides an organic compound of following formula and an organic light emitting diode and an OLED device including the organic compound.
US11802089B2
A process for manufacturing a ceramic matrix composite part, includes infiltrating a fibrous structure including a powder composition with a melt infiltration composition including at least silicon in order to form a ceramic matrix in the porosity of the fibrous structure, the powder composition including at least silicon carbide particles, wherein the silicon carbide particles have a bimodal size distribution with a first set of silicon carbide particles having a first average size and a second set of silicon carbide particles having a second average size smaller than the first average size, the number of particles in the first set being greater than the number of particles in the second set.
US11802088B1
High-entropy ultra-high temperature ceramics (HE-UHTC) coatings deposited on substrates, as well methods for depositing the HE-UHTC coatings on the substrates, are provided. An HE-UHTC electrode can be fabricated via spark plasma sintering (SPS) and then a thin coating of the HE-UHTC can be deposited in a precision-controlled manner on a substrate via an electro-spark deposition process.
US11802087B2
The present invention discloses a dielectric ceramic formula enabling one to obtain a multilayer ceramic capacitor by alternatively stacking the ceramic dielectric layers and base metal internal electrodes. The dielectric ceramic composition comprises a primary ingredient: [(Na1-xKx)sA1-s]m[(Nb1-yTay)uB1vB2w)]O3 wherein: A, B1, B2, x, y, s, u, v, w and m are defined.
US11802086B2
An anti-fouling coating film of the present invention includes a component (A): zirconium; a component (B): lanthanum; and a component (C): at least one selected from the group consisting of silicon, phosphorus, and boron, in which in a case where masses of the component (A), the component (B), and the component (C) are used by being converted into masses of oxides thereof, total mass of the component (A) and the component (B) with respect to a mass of the anti-fouling coating film is 90% or more and 95% or less, and in a case where X is defined by X=mass of component (B)/(total mass of component (A)+component (B))×100, X is 20% or more and 50% or less, and the mass of the component (C) to the mass of the anti-fouling coating film is 5% or more and [6+(X−20)/6]% or less.
US11802085B2
Disclosed is to provide a composite structure used as a member for a semiconductor manufacturing apparatus with which low-particle generation can be improved, as well as a semiconductor manufacturing apparatus including the same. A composite structure including a base material and a structure that is provided on the base material and has a surface, in which the structure comprises Y3Al5O12 as a main component, and has an indentation hardness being larger than 8.5 GPa features excellent low-particle generation and is suitably used as a member for a semiconductor apparatus.
US11802068B2
The present application relates to a preparation method for recycling inorganic salt in printing and dyeing wastewater and comprises the following process steps: S1, performing impurity removal, softening, COD removal and decoloration on reverse osmosis (RO) membrane concentrated water to obtain pretreated wastewater; S2, performing two-stage electrodialysis on the wastewater obtained in step S1: returning fresh water obtained in a first-stage electrodialysis desalination chamber to a front end of the RO process, and taking saline water obtained in a concentration chamber as raw water of a second-stage electrodialysis desalination chamber and a second-stage electrodialysis concentration chamber; and returning the fresh water obtained by the second-stage electrodialysis desalination chamber to the first-stage electrodialysis concentration chamber; and S3, dealkalizing the concentrated saline water obtained in the step S2 and then adjusting the pH value to obtain concentrated saline water capable of being reused for cloth dyeing in a printing and dyeing mill.
US11802065B2
An induced sludge bed anaerobic reactor system that includes at least two stages of bioreactor processing, a first-stage feeding system, a second-stage feeding system, a pH balancing system, an effluent recirculation system, a gas management system, at least one nitrogen reduction system, and a controller. In addition, the nitrogen reduction system(s) if configured for reducing an amount of one or more nitrogen compounds in a substrate mixture sufficient to procedure a non-toxic substrate mixture with respect to anaerobic digestion of the non-toxic substrate by the induced sludge bed anaerobic reactor system.
US11802064B2
A capacitive deionization desalination device is provided. The capacitive deionization desalination device includes a mesh spacer and two carbon nanotube composite electrodes. The mesh spacer is located between the two carbon nanotube composite electrodes. Each carbon nanotube composite electrode includes at least one carbon nanotube film structure and a composite carbon layer, and the carbon nanotube film structure includes at least two carbon nanotube films, and the composite carbon layer includes activated carbon and carbon black, and the composite carbon layer is located on the carbon nanotube film structure.
US11802059B2
A porous carbon material having a value of a specific surface area by a nitrogen BET method of 1×102 m2/g or more, a volume of fine pores by a BJH method of 0.3 cm3/g or more, and a particle size of 75 μm or more, alternatively, a porous carbon material having a value of a specific surface area by a nitrogen BET method of 1×102 m2/g or more, a total of volumes of fine pores having a diameter of from 1×10−9 m to 5×10−7 m, obtained by a non-localized density functional theory method, of 1.0 cm3/g or more, and a particle size of 75 μm or more.
US11802053B2
An apparatus for fabricating diamond by carbon assembly, which comprises: a) a hydrocarbon radical generator in operable connection with b) a mass flow conduit extending from the hydrocarbon radical generator in a) to an interface and into a primary magnetic accelerator containing one or more electromagnets in operable connection with c) a diamond fabrication reactor comprising a diamond forming deposition substrate. Also disclosed is a method for fabricating diamond by shockwaves using the disclosed apparatus.
US11802050B2
A method for producing a haloamine solution with reduced amounts of halogen oxyanions including (a) the on-site generation of a halogen-containing oxidant, such as a solution and (b) reacting on-site the halogen-containing oxidant with a nitrogen source, to thereby produce the haloamine solution.
US11802036B2
A beverage dispenser uses-high ratio concentrates to mix on-demand beverages. The high-ratio concentrate is pre-mixed with an alkaline water to allow for improved blending performance in the final beverage. The beverage recipe may be customized by the user to suit personal tastes. Aspects of the beverage dispenser also may include the ability to dispense room temperature, chilled, heated, sparkling, or highly alkaline beverages. Operation of a user interface to receive a beverage order includes the ability to display and employ user interfaces present on both a display on the beverage dispenser and an application on a mobile device. In some aspects, both user interfaces may be used simultaneously to receive user input. Methods of dispensing a beverage using the beverage dispensing systems are also discussed.
US11802035B2
A clamping device for holding a container in a container handling device, for example for holding a beverage container by a neck portion, includes a first clamping arm arranged on a support plate pivotably about a first pivot shaft and having a holding portion for contact against the container to be held, and a second clamping arm arranged on the support plate pivotably about a second pivot shaft and having a holding portion for contact against the container to be held. The first pivot shaft and the second pivot shaft respectively have a cylinder pin portion for forming a form closure, radially to the longitudinal direction of the pivot shaft, with a bore in a support of a container handling device.
US11802025B2
According to an example aspect of the present invention, there is provided a remote control workstation for controlling more than one type of load handling equipment. The remote control workstation is configured for communications with a plurality of types of load handling equipment and configured to cause connecting to one of said load handling equipment, determining a type of the connected load handling equipment, and in response to establishing a connection between the remote control workstation and said load handling equipment, displaying on a user interface of the remote control workstation a load handling equipment type specific control view from a plurality of load handling equipment type specific control views in accordance with a load handling equipment type of said load handling equipment.
US11802024B2
The present disclosure is directed to the transport of one or more loads of items including building materials and/or other items to one or more target surfaces including one or more elevated surfaces. The present disclosure is also directed to the holding of one or more loads of items including building materials and/or other items during transport to one or more target surfaces including one or more elevated surfaces. The present disclosure is also directed to the holding of one or more loads of items including building materials and/or other items on one or more target surfaces including one or more elevated surfaces.
US11802021B2
A locking device for a guide rail is disclosed. The device includes a first edge including a plurality of teeth shaped projections. The first edge compresses and locks a first surface of a covering sheet placed on a base ring. The device also includes a second edge opposing the first edge. The second edge includes a V-shaped groove, wherein the second edge is disposed to hold at least one furrow of the guide rail for interlocking. The first edge and the second edge of the locking device locks air gap between the covering sheet, the guide rail connecting one or more surfaces of the base ring and a vertical pillar coupled to the guide rail.
US11802018B2
During flipping sheets may fold upon themselves under the influence of gravity. To prevent a sheet stacker is provided with a holding device for releasably holding at least a portion of the sheet at least partially during the flipping of the sheet by a sheet flipping device, wherein the holding device is configured for movement of the held portion of the sheet in a first direction perpendicular to the flipping axis.
US11802017B2
An ultrasonic apparatus includes a first ultrasonic sensor that transmits an ultrasonic wave to an object and receives the ultrasonic wave reflected by the object, a second ultrasonic sensor that transmits an ultrasonic wave to the object and receives the ultrasonic wave reflected by the object, an determination circuit that outputs an error signal when the difference between a first distance between the first ultrasonic sensor and the object calculated based on ultrasonic wave transmission and reception processing using the first ultrasonic sensor and a second distance between the second ultrasonic sensor and the object calculated based on ultrasonic wave transmission and reception processing using the second ultrasonic sensor is equal to or greater than a threshold value.
US11802010B2
An article transport facility includes a transport conveyor (34) and a weighing device (24), which includes a support portion (28) for supporting a container (C1) and a measuring portion (30) configured to measure a weight of the container (C1) supported by the support portion (28). The article transport facility is configured to perform a state change between a withdrawn state in which the support portion (28) is withdrawn downward relative to a transport surface (34A) and a protruding state in which the support portion (28) protrudes upward relative to the transport surface (34A) by moving the support portion (28) and the transport conveyor (34) relative to each other in a vertical direction (Z). A support surface (28A) of the support portion (28) is inclined such that one corner portion (8A) of multiple corner portions (8) located at corners of the container (C1) is lower than the other corner portions (8).
US11802003B1
The conveyor belt cleaning system is an add-on apparatus for a grocery store checkout conveyor. The device automatically dispenses a disinfectant liquid on the underside of the belt in a continuous manner. The disinfectant is pumped from an open rectangular reservoir that is the same width as the belt. An electric pump dispenses the disinfectant from at least one spray nozzle at the leading edge of the reservoir. A squeegee is secured at the trailing edge of reservoir removes excess disinfectant which in turn falls back into the reservoir for reuse.
US11802000B2
A container handling vehicle for picking up storage containers from a three-dimensional grid of an underlying storage system includes: a first set of wheels, arranged at opposite portions of a vehicle body of the container handling vehicle, for moving the vehicle along a first direction on a rail system of the grid; and a second set of wheels for moving the vehicle along a second direction on the rail system of the grid. The container handling vehicle further comprises a first section and a second section arranged side-by-side such that a centre point of a footprint of the first section (F1) is arranged off centre relative a centre point of the footprint of the vehicle body (FV), and a size ratio of the footprint of the first section (F1) relative a footprint of the second section (F2) is at least 2:1.
US11801991B1
A composite pod body that is compatible with the internal carriage mounting of an aerial vehicle for stowage of equipment or other items during long term aerial travel or deployment. The pod system may have large access doors with quick release latches and removable end caps for ergonomic access and versatility of stowage. The pod design may maximize the usable volume of the internal carriage. Further, standard NATO lug spacing may be utilized to ensure military compatibility. The pod may also have anti-roll or stabilization feet integrated with the body to ensure safety. The composite body may be lightweight when compared to legacy generation pods.
US11801987B2
A woven plastic bag having features that further prevent leakage of contents out of the bag, or infestation of organisms into the contents of the bag is provided. In various aspects the bag can be fabricated from a woven polymer layer and a film layer, can form a pinch bottom bag, and can have one or both sides include graphics and/or printing. The bag can also provide a top end and/or a bottom end either or both of which provide a discrete area which may contain discrete graphics and/or printing. The bag can have an end with a step cut configuration, wherein the step cut configuration includes one or more angled and/or radial cuts between separations.
US11801984B2
A blank for forming a tray, wherein the blank includes a first panel extending along a lateral axis configured to form an outer side of an erected tray and a second panel extending along the lateral axis coupled to the first panel by a fold line, the second panel being configured to form an inner side of the erected tray. Each of the first and second panels includes a base section, a first lateral section foldably coupled to the base section, a first end section foldably coupled to the first lateral section, a second lateral section foldably coupled to the base section, and a second end section foldably coupled to the second lateral section.
US11801979B2
A container with a security lock is provided. The container may have a lid (or “top”) portion and a bottom portion. The lid portion may have an exterior cover, a first disc, a second disc and a third disc. The first disc may have a plurality of indented downward partial trapezoids. The second disc may also have a plurality of nearly identical, upwardly extending partial trapezoids wherein the plurality of indented partial trapezoids of the first disc may be temporarily and selectively located between the plurality of partial trapezoids of the second disc in order to allow the lid to be rotated and the container therein opened. The third disc may be made of a thin material that allows the container to remain substantially airtight.
US11801961B2
A twin-tube tubular bag machine having two longitudinal sealing elements for forming two parallel film tubes, two parallel transverse sealing jaws for forming sealed tubular bags, and two filling devices for filling the tubular bags. A dosing device is disposed upstream of each of the filling devices for dosing a prespecified filling quantity of the filling material to be filled into the tubular bags. A transfer element having several transfer containers is provided between the filling devices and the dosing device. The filling material is transferred from the dosing device to the transfer containers in an input station. The transfer containers are transported to a pairing of two dispensing stations along a transfer line, the filling material is transferred from the transport containers to the two filling devices, and the transfer containers are transported back to the input station along a return transfer line.
US11801960B2
A system for wireless monitoring of operating and production parameters of a clipping machine for food production having a sealed housing protected at least against moisture. The system comprises at least one measuring and control device for controlling the production process and measuring the operating and/or production parameters of the machine, sensors for determining operating parameters of the machine, devices for determining production parameters of the machine, at least one wireless communication device, a user interface and display device, and at least one smart device having at least an optical reading unit, wherein the at least one wireless communication device is configured to generate login details for wireless communication and encrypt the login details into a binary code which can be read by the optical reading unit of the smart device via the user interface and display device.
US11801952B2
A platform for pallet wrapping machines includes a fixed base resting on the ground and a turntable which rotates relative to the base and in which a plurality of rollers is integrated, the rollers projecting from it in such a way as to support a pallet and provided with a movement device integrated with them, in such a way that the platform has a total thickness not greater than 10 centimeters.
US11801950B2
The present document presents a system and a method for packaging powders in containers (S) through a hopper (T) and a first tube (TC) connected to the hopper (T). Air is sucked both in the area of the first tube and in the area of the hopper. The powder is then drawn directly from inside the hopper thus keeping the flow rate and the degree of compacting of the system constant. Moreover, the powder sucked inside the first tube is thus compacted and can be conveyed compacted towards the outlet. In this way it is possible to control the dosing of the product exiting from the system with high precision.
US11801948B2
An orbital trajectory planning system includes a first computer processor environment configured to preprocess data for providing to a physics-based n-body simulation model, the first computer processor environment including a graphical user interface (GUI) for receiving input from a user. The system also includes a second computer processor environment running at least partially trained neural network software that has been trained to perform nonlinear mapping of the output of the n-body simulation model to a result related to a proposed trajectory for a spacecraft, the second computer processor environment receiving input information from the first computer processor environment. Further the system relates to a third computer processor environment configured to receive data related to the output from the neural network of the second computer processor environment, the third computer processor environment providing user useable output through a GUI running on the third computer processor environment.
US11801936B2
Embodiments are directed to a flight control system for a helicopter comprises a pilot interface configured to receive a control input, at least one electronically controlled actuator, and a computing device configured to translate the control input to an actuator command, wherein the computing device is further configured to apply yaw rate limits to the actuator command to avoid loss of tail rotor effectiveness. The yaw rate limits are associated with a vortex ring state (VRS) envelope for a tail rotor of the helicopter. The electronically controlled actuator comprises a tail rotor actuator. The control input is a pedal input.
US11801935B2
A propeller, a propeller kit, a power assembly, a power kit and an unmanned aerial vehicle (UAV). The propeller includes a hub and at least two blades connected to the hub. The hub is detachably mounted on a corresponding drive apparatus by a mounting member corresponding to the hub, so that the propeller is mounted on the corresponding drive apparatus. A surface, facing the mounting member, of the hub is provided with a first fitting portion. A surface, facing the hub, of the mounting member is provided with a second fitting portion corresponding to the first fitting portion. The first fitting portion matches the second fitting portion. In the foregoing manner, a user can be prevented from incorrectly mounting a forward propeller and a counter-rotating propeller during the use of a quick-detachable propeller in the embodiments of the present application.
US11801927B2
The present invention disclosed a paddle, which includes a blade and a hollow lower shaft that connects to the blade. The hollow lower shaft is capable of receiving a rod and an upper shaft capable of entering and moving within said lower shaft; with one end of the upper shaft connected to the rod and able to move simultaneously with the upper shaft within the lower shaft. Wherein, the material of the rod within the hollow lower shaft is different from that of the hollow lower shaft, and the paddle is less likely to break instantaneously.
US11801924B2
Positioning an electrode through a drain plug on the boat to align transmitted pulses with a water intake of the motor.
US11801914B2
A flexible coupling mechanism may be used to suspend a structural component, such as a propulsion pod, from a support member, such as a strut of a hydrofoil watercraft. The flexible coupling mechanism may include multiple vibration isolating mounts configured to extend through the support member to suspend the structural component. The vibration isolating mounts may include a plurality of elastomeric bushings configured to prevent direct contact between a component rigidly coupled to the support member and a component rigidly coupled to the structural component. The elastomeric bushings may include a tapered outer profile configured to provide a nonlinear force feedback profile in response to rotation of the support member relative to the structural component.
US11801910B2
A scooter includes a frame which has a footboard and supports a rear wheel, a steering column provided with a front wheel pivotably mounted on the frame, and a motor provided with a drive shaft coupled to the rear wheel via a transmission system. The transmission system includes a rear transverse shaft having a first end portion and a second end portion rotatably coupled to the rear wheel; —a gear system having a sprocket coupled rotatably to the first end portion and in meshing engagement with a toothed gear rotatably coupled to the drive shaft; and —a rear structure attached to the frame, supporting the gear system and the rear transverse shaft, and extending laterally along one side only—right or left—of the rear wheel, such that the second end portion extends from the rear structure to support the rear wheel in a cantilevered fashion.
US11801908B2
A bicycle holding device for holding a bicycle that has a perforation at the bottom end of each of the left and right fork blades of the front fork thereof is disclosed to include a bicycle holder frame settable on the ground or wall, and a front fork support rod located in the bicycle holder frame and passing through the perforations of the left and right fork blades of the front fork. Thereby, the bicycle holding device of the present invention can allow the user to easily complete bicycle parking, and can provide good stability after the completion of the parking.
US11801883B2
The disclosure relates to a steering system for a motor vehicle, which is designed as a steer-by-wire steering system and comprises a rack, an electric drive for longitudinal displacement of the rack, a worm gear and a drive shaft which is in toothed engagement with the rack. The electric drive is connected to the drive shaft by the worm gear so as to transmit torque.
US11801881B1
The support dolly for hitch-mounted accessories includes a center plate, a plurality of outrigger tubes, a plurality of wheel assemblies, a right angle adapter, and a plurality of lock pins. The support dolly for hitch-mounted accessories may be operable as a stationary stand for storing a hitch-mounted accessory when the plurality of wheel assemblies are not deployed or as a dolly for moving the hitch-mounted accessory when the plurality of wheel assemblies are deployed. As non-limiting examples, the hitch-mounted accessory may be an accessory that couples to a trailer hitch receiver tube of a tow vehicle such as a bike rack, a winch, a generator, a cargo basket, or a dirt bike carrier. The support dolly for hitch-mounted accessories may be reconfigurable to alter the footprint of the support dolly for hitch-mounted accessories or to couple multiples of the center plates together.
US11801877B1
A railcar anti-scissoring system includes a base controller positioned within a train locomotive that sends a launch initiation command to railcar-stabilizing units when detecting rapid deceleration indicative of a collision or derailment. The stabilizing units include a receiver secured to the rear end of each rail car and a coupling unit attached to the front end of each rail car. The coupling unit houses a deployable locking rod that is thrust into a mating cavity in the receiver upon receipt of the launch command. The deployed locking rod maintains the host railcar and the preceding railcar in a linear orientation during a rapid deceleration to prevent jackknifing.
US11801873B2
An autonomous driving control apparatus for a vehicle includes: a processor to determine activation of an autonomous driving function depending on whether a current driving situation satisfies an activation condition of the autonomous driving function during autonomous driving control; and a storage configured to store a set of instructions and data for determination and performance by the processor. In particular, the processor controls a vehicle to satisfy the activation condition and then determines activation of the autonomous driving function when the activation condition is not satisfied and a request to activate the autonomous driving function is inputted from a user.
US11801871B1
Example aspects of the present disclosure relate to an example computer-implemented method for predicting the intent of actors within an environment. The example method includes obtaining state data associated with a plurality of actors within the environment and map data indicating a plurality of lanes of the environment. The method include determining a plurality of potential goals each actor based on the state data and the map data. The method includes processing the state data, the map data, and the plurality of potential goals with a machine-learned forecasting model to determine (i) a forecasted goal for a respective actor of the plurality of actors, (ii) a forecasted interaction between the respective actor and a different actor of the plurality of actors based on the forecasted goal, and (iii) a continuous trajectory for the respective actor based on the forecasted goal.
US11801867B2
A vehicle control device of a vehicle includes: an action plan creating part that creates an action plan for autonomous driving by the vehicle; and a distance detection part that outputs detection information on detection of an object. The action plan creating part includes a collision probability map setting part configured to, when the distance detection part detects an obstacle, determine a collision probability map, which is a two-dimensional map of a collision probability distribution representing likelihood of a collision between the vehicle and the detected obstacle in a two-dimensional space of a location and a speed. The action plan creating part is configured to create a current action plan based on the collision probability map, a predetermined target collision probability, and a current location and a current speed of the vehicle.
US11801864B1
A vehicle computing system may implement techniques to determine an action for a vehicle to perform based on a cost associated therewith. The cost may be based on a detected object (e.g., another vehicle, bicyclist, pedestrian, etc.) operating in the environment and/or a possible object associated with an occluded region (e.g., a blocked area in which an object may be located). The vehicle computing system may determine two or more actions the vehicle could take with respect to the detected object and/or the occluded region and may generate a simulation associated with each action. The vehicle computing system may run the simulation associated with each action to determine a safety cost, a progress cost, a comfort cost, an operational rules cost, and/or an occlusion cost associated with each action. The vehicle computing system may select the action for the vehicle to perform based on an optimal cost being associated therewith.
US11801863B2
Provided is a vehicle control device configured to: generate a target trajectory of a vehicle; and determine whether change in speed of a target steering angle in a first period is equal to or larger than a first threshold value and whether change in speed of the target steering angle in a second period is equal to or larger than a second threshold value; and change, in a case where the driving mode of the vehicle is a second driving mode, the driving mode of the vehicle to a first driving mode when the change in speed of the target steering angle in the first period is determined to be equal to or larger than the first threshold value or when the change in speed of the target steering angle in the second period is determined to be equal to or larger than the second threshold value.
US11801859B2
A method for operating a driver assistance system for a motor vehicle driven in an at least partially automated manner includes learning a trajectory in a learning mode for driving the vehicle in a first automated manner along the trajectory. Subsequently, the vehicle is driven in the first automated manner along the learnt trajectory in an operating mode following the learning mode. While the vehicle is being driven along the trajectory in the operating mode, at least one transition from a private area to a public area is detected. Additional data, including current traffic data related to driving the vehicle in the public area, is acquired and provided for the driver assistance system. The motor vehicle is driven along the learnt trajectory in a second automated manner in the public area using the additional data.
US11801857B2
The disclosure relates to a control method for driver assistance. The method includes: receiving positioning information of a vehicle; obtaining information about a road structure ahead of the vehicle based on the positioning information; and determining, based on the information about the road structure, whether an alarm for a sharp bend is needed. The disclosure further relates to a control device for driver assistance, a computer storage medium, and a vehicle.
US11801853B2
An onboard display device is installed in a vehicle configured to enable autonomous driving. The onboard display device includes an information acquisition section and a display control section. In a case in which the vehicle attempts to merge from a traveling lane into a merging destination lane during autonomous driving, the information acquisition section acquires information regarding a point at which the attempt will be aborted, before the vehicle arrives at the point. The display control section displays the information regarding the point that is acquired by the information acquisition section, before the arrival at the point. at a display portion that is provided within a vehicle cabin of the vehicle.
US11801851B2
Systems and methods for controlling a failover response of an autonomous vehicle are provided. In one example embodiment, a method includes determining, by one or more computing devices on-board an autonomous vehicle, an operational mode of the autonomous vehicle. The autonomous vehicle is configured to operate in at least a first operational mode in which a human driver is present in the autonomous vehicle and a second operational mode in which the human driver is not present in the autonomous vehicle. The method includes detecting a triggering event associated with the autonomous vehicle. The method includes determining actions to be performed by the autonomous vehicle in response to the triggering event based at least in part on the operational mode. The method includes providing one or more control signals to one or more of the systems on-board the autonomous vehicle to perform the one or more actions in response to the triggering event.
US11801849B2
An electrically controlled differential gear is disposed between a right front wheel and a left front wheel of a vehicle. The electrically controlled differential gear includes a clutch mechanism that limits a differential operation of the electrically controlled differential gear. A second ECU (control portion) obtains information as to failure associated with actuation of a right front electric brake mechanism. The second ECU obtains a physical amount relating to a required braking force which is applied to the left front wheel and the right front wheel. The second ECU outputs a differential limiting control command for limiting the differential operation of the electrically controlled differential gear to the clutch mechanism (or more specifically, a differential ECU that controls the clutch mechanism) based on the information as to the failure and the physical amount relating to the required braking force.
US11801848B2
Systems and methods are provided for adjusting a control of a vehicle system based on a condition of an occupant. The system includes a replaceable or upgradeable electronic skin removably coupled to an interior vehicle component. The electronic skin includes at least one sensor positioned therein, configured to monitor/obtain a biometric, physiological, or wellness condition measurement from an occupant. The system includes one or more processors and a memory communicably coupled thereto. An occupant comfort module is provided including instructions that, when executed, collect and monitor feedback from the at least one sensor; determine that the feedback exceeds a predetermined threshold; and determine an adjustment for a vehicle system based on the feedback. A control module may be provided including instructions that, when executed by the one or more processors, cause the vehicle system to change at least one setting based on the adjustment determined by the occupant comfort module.
US11801844B2
Systems and methods for controlling a vehicle using operational constraints, including friction estimates are disclosed. Friction estimation include estimating a tire-road coefficient of friction using bins and envelopes. Bounding envelopes are configured to ensure that stability of the vehicle is maintained. The friction estimate is used to define the bounding envelopes. Further, the bounding envelopes are received as feedback into the friction estimation, itself. Based on the bounding envelope, the friction estimation can be adjusted. Then, the adjusted friction estimation can be fed back to reshape the bounding envelopes. Multiple bins can be used to evaluate an operating range of friction. Each bin can be used to compare actual vehicle dynamics with expected dynamics based on the estimation using the range assigned to that bin. Multiple bins and multiple controllers can run in parallel to re-estimate friction considering the vehicle dynamics over time.
US11801842B2
Examples of the present disclosure describe systems and methods for determining an estimated ambient air temperature in an environment in which a vehicle is operating. The estimated ambient air temperature may be compared to an ambient temperature sensor value. The comparison may be used to determine whether an ambient air temperature sensor of the vehicle is functioning properly or if an error notification or fault code should be triggered.
US11801835B2
A controller for a vehicle is configured to determine the position of the accelerator pedal with respect to a reference accelerator pedal position (aref); and either determine a torque output in dependence on an acceleration pedal map if the position of the accelerator pedal is greater than the reference accelerator pedal position (aref); and, determine a torque output in dependence on a deceleration pedal map if the position of the accelerator pedal is less than the reference accelerator pedal position (aref).
US11801830B2
A control device for vehicle is provided, and includes a communicator configured to receive first image information from a camera device and a processor coupled to the communicator and configured to: extract label information in the first image information; perform edge detection on the label information and extract a total number of edges; normalize the total number of edges to form a first label clarity; and when the first label clarity is greater than or equal to a preset threshold, control the vehicle to move to a parking position according to the first image information. A control method for vehicle is also provided. The present disclosure can effectively reduce the number of starts and stops of the vehicle and shorten the parking time of the vehicle.
US11801829B2
An in-vehicle device, a system and a method for automatic parking assistance. The in-vehicle device includes a communication interface through which the in-vehicle device receives a parking navigation path from an external device, the parking navigation path including linear road sections and/or arc road sections; and a parking controller coupled with the communication interface. The parking controller is configured to identify line-shape features of each road section; determine whether the vehicle can travel along a road section based on line-shape features of the road section; in the case that the determination is affirmative, control a driving behavior of the vehicle such that the vehicle travels along the road section; in the case that the determination is negative, determine a new travelling path and control a driving behavior of the vehicle such that the vehicle travels along the new travelling path.
US11801828B2
A parking assistance device includes a recognition part that is configured to acquire recognition information through recognition of surroundings of a host vehicle, a maneuver controller that is configured to perform maneuver control to park the host vehicle in a parking region based on the recognition information, a maintain stop position controller that is configured to keep the host vehicle stationary after the host vehicle is stopped by the maneuver control of the maneuver controller until a predetermined operation is received from a driver, a determination part that is configured to determine a type of the parking region in which the host vehicle is to be parked with the maneuver controller; and a decision part that is configured to determine, in accordance with the type of the parking region that is determined by the determination part, a parking reference location that is used to park the host vehicle in the parking region.
US11801827B2
An automatic parking system which controls a vehicle so as to cause the vehicle to be moved to a parking place and accommodated in a parking frame provided in the parking place includes a route where magnetic marker is laid so as to be detectable by using a magnetic sensor array provided to the vehicle, RFID tag providing tag information capable of identifying laying position of the magnetic marker, and a control server device which identifies a vehicle position based on the laying positions of the magnetic markers, allowing highly-accurate identification of the position of the vehicle to be forwarded and allowing operation with high reliability.
US11801825B2
An unmanned ground vehicle (UGV) includes one or more motors configured to drive one or more wheels of the UGV, a memory storing instructions, and a processor coupled to the one or more motors and the memory. The processor is configured to execute the instructions to cause the UGV to determine location information of a movable target; calculate a direction and a speed for the unmanned ground vehicle based on the determined location information; and drive the one or more motors to move the unmanned ground vehicle in the calculated direction at the calculated speed to follow the movable target when the movable target moves.
US11801799B2
In order to absorb collision energy so as to prevent an increase in reaction force against a pedestrian to a level higher than or equal to a certain level during collision, a bumper absorber of the present invention includes: a trunk part that extends in an X direction and that is simply compressed in the X direction in response to an impact; and a branch part that branches off from the trunk part toward a rear of a vehicle body, the branch part having a branching part in which the branch part branches off from the trunk part and which is provided with a breakage inducing part that causes breakage between the trunk part and the branch part in response to the impact.
US11801798B2
A joint connector configured to have a plurality of wire harnesses connected thereto and join the plurality of wire harnesses, the joint connector including a sub-connector configured to have connectors of the plurality of wire harnesses inserted therein, a housing inside which the sub-connector is provided, a plurality of joint terminals arranged in parallel with each other in a protruding state within the housing and respectively connected to the connectors of the plurality of wire harnesses, and a relay unit provided in the housing and connected to the plurality of joint terminals, the relay unit being configured to, based on information included in data transmitted from an in-vehicle ECU or in-vehicle sensor connected to the plurality of wire harnesses, perform relay control of the data between the plurality of joint terminals.
US11801796B2
A garnish configured to enable use of a common door for a two-door vehicle and a four-door vehicle. The garnish may have a body. The body may be directly mountable onto a carriage of the two-door vehicle between an outer panel and a rocker panel of the two-door vehicle. The body may have an edge that is flush to a rear edge of the common door when mounted. The body may have at least two edges forming approximately a 90-degree angle.
US11801789B2
An example emergency vehicle siren system can include: one or more emergency lights; a siren; and a controller including a processor and memory, the memory encoding instructions which, when executed by the processor, cause the controller to modify a sound of the siren based upon a context of the vehicle, the context including at least one of a speed and location of the vehicle.
US11801788B2
A vehicle lamp assembly includes a lamp finisher, a knob and a retainer. The lamp finisher defines an exterior housing for a light source of the vehicle lamp assembly. The knob is movable with respect to the lamp finisher to operate the light source between an ON state and an OFF state. The retainer is sandwiched between a portion of the lamp finisher and a portion of the knob. The knob is retained to the lamp finisher by the retainer.
US11801782B2
A seat pad 1 is a seat pad including a resin foamed body 50, and a sheet member 70 buried in the resin foamed body, and when a direction orthogonal to a right-left direction and a thickness direction of the seat pad is referred to as an extending direction of the seat pad, at least a central part of the sheet member is curved in a convex shape on a back surface side of the seat pad in the extending direction.
US11801780B2
Embodiments related to active vibration isolation systems for a vehicle seat, as well as their methods of use, are disclosed. In some embodiments, an active suspension system may be configured to support a seat above a floor of a vehicle. The active suspension system may include two or more actuators that may be operated cooperatively to control both the roll and heave of the vehicle seat. In some instances, these actuators may also be non-back-drivable actuators. Additionally, in some embodiments, an active suspension system may include one or more torsion springs that apply torques in parallel with associated actuators of the active suspension system to support at least a portion of the loads applied to the active suspension system during operation.
US11801779B2
A seat for a vehicle is provided. In the seat for a vehicle, a second row center seat and a second row side seat are mounted using a partition located behind a driver seat, and the second row center seat is configured to have a movable structure and a mounting location thereof is movable toward the partition wall or a vehicle body side part when necessary.
US11801777B2
A load support apparatus for a lumbar support assembly is proposed, in which reinforcing ribs are arranged on a lateral surface and a front surface of a concave portion, the load support apparatus maintaining bearing power for supporting an occupant and having a reduced weight. The load support apparatus includes a main support unit including a main plate formed in the shape of a plate, a concave portion formed by one portion of the main plate protruding backward, with a groove being formed in front of the concave portion, and a rib portion formed by protruding from the main plate toward the groove or backward from the main plate.
US11801776B2
A vehicle seating system includes a seatback pivotally coupled to a seat base. The seatback is operable between an upright position and a reclined position. A lift assembly is operably coupled to the seat base. The lift assembly is operable between a disengaged position and an engaged position. A position sensor is coupled to the lift assembly via a ball joint, wherein the ball joint and the position sensor adjust with movement of the lift assembly. A seat controller communicatively is coupled to the position sensor, wherein the seat controller determines if the lift assembly is in the disengaged position or has moved to the engaged position based on position data received from the position sensor.
US11801772B2
A thermal management module includes a component carrier, at least two, typically multiple electrically controllable function components for temperature-controlling at least one vehicle component of a motor vehicle, which are detachably or non-detachably connected to the component carrier, at least one electrical control unit, which for electrically controlling at least two, typically multiple, particularly typically all of the function components include a control electronic system, which via at least one electrical control line path and/or via a component field bus is electrically connected to the respective function component and arranged in a housing of the control unit, wherein the housing of the control unit is detachably or non-detachably fastened to the component carrier and/or to at least one of the function components.
US11801769B1
Special purpose power systems for electric vehicles, control methods and special purpose electric vehicles are disclosed. Special purpose power systems control and manage loads in special purpose devices used in special purpose vehicles such as first responder vehicles. Disclosed systems and methods offer systematic control load shedding according to user designated load circuit priorities to maintain special purpose system capabilities without degrading the electric vehicle traction system and provide control of multiple circuit connections for redundant, fault tolerant operations.
US11801764B2
The present invention relates to the technical field of vehicles, and provides an energy conversion device and a vehicle. The energy conversion device includes a reversible pulse-width modulation (PWM) rectifier, a motor coil connected with the reversible PWM rectifier, a one-way conduction module, and a capacitor. A DC charging circuit or a DC discharging circuit is formed by an external DC port with an external battery by using the energy conversion device, and a driving circuit is formed by the external battery with the reversible PWM rectifier and the motor coil in the energy conversion device. The one-way conduction module is connected between a first end of the capacitor and a second end of the external DC port, or the one-way conduction module is connected between a second end of the capacitor and a first end of the external DC port.
US11801751B2
An image display apparatus includes a controller, a sensor, and a display. The controller is configured to acquire sensor information from the sensor, recognize surrounding real space from the sensor information, extract an available parking spot in the real space, and project a virtual image indicating the parking spot onto the real space using the display.
US11801745B2
A separation element is configured to separate a working chamber from a compensation chamber of a hydraulic anti-vibration module for mounting an engine on a vehicle body. The separation element includes a first duct extending between a first mouth and a second mouth. In embodiments, the first mouth is provided in a first face of the separation element and is configured to be fluidically connected to the working chamber, and the second mouth is provided in a second face of the separation element and is configured to be fluidically connected to the compensation chamber. In embodiments, the first mouth includes a plurality of openings.
US11801743B2
A configurable, modular vehicle on common chassis platform, and associated systems and methods are disclosed herein. In one embodiment, a configurable modular vehicle includes: a chassis, a power plant module configured to generate electrical energy, and a drive train module. The drive train module includes: at least one traction motor configured to receive electrical energy from the power plant module, a transmission configured to transfer torque from the traction motor to a drive axle, and the drive axle configured to transfer torque to drive wheels, and a control system module configured to control components of the power plant module and the drive train module. The interfaces of the power plant module and the drive train module are predefined, and different types of the power plant modules and the drive train modules are interchangeable within their respective predefined interfaces.
US11801730B1
There is provided a method comprising: determining an occupancy status of a first region of a vehicle; determining, based at least in part on the occupancy status, a first climate control setting for the first region; controlling a climate control system of the vehicle to adjust a climate of the first region according to the first climate control setting; determining that a second region of the vehicle is unoccupied, wherein the second region is fluidly connected to the first region; determining a second climate control setting, wherein the second climate control setting is based at least in part on the occupancy status of the first region and characteristic data associated with a predicted potential change in occupancy status for the second region; and controlling the climate control system to adjust a climate of the second region according to the second climate control setting.
US11801727B2
One example provides a thermal management system for an electric vehicle including a pump to pump a thermal transfer fluid through a number of circulation loops, an electric heater to heat the thermal transfer fluid, a heat exchanger to expel heat from the thermal transfer fluid, a number of valves, and a number of fluid pathways fluidically interconnecting the pump, heater, heat exchanger and valves. The valves being controllable to a number of different positions to form the number of circulation loops, the number of circulation loops including a battery heating circulation loop extending through the heater for heating a battery pack of the vehicle, a secondary components cooling circulation loop extending through the heat exchanger to cool secondary components of the vehicle, including a motor and a motor controller, and a battery cooling circulation loop extending through the heat exchanger to cool the battery pack.
US11801726B2
Systems and methods for determining the location of a vehicle are disclosed. In one embodiment, a method for localizing a vehicle includes driving over a first road segment, identifying by a first localization system a set of candidate road segments, obtaining vertical motion data while driving over the first road segment, comparing the obtained vertical motion data to reference vertical motion data associated with at least one candidate road segment, and identifying, based on the comparison, a location of the vehicle. The use of such localization methods and systems in coordination with various advanced vehicle systems such as, for example, active suspension systems or autonomous driving features, is contemplated.
US11801718B2
A trolley that couples to a tow saddle is provided. The trolley includes an upper plate and a lower plate. The upper and lower plate are secured against a rear portion of a tow saddle. One or more support bars are coupled to the upper plate. The bars provide structural support for the upper plate and deflect a chain that transits apertures in the upper plate.
US11801715B2
A tire includes a tread portion including four circumferential grooves between outboard and inboard tread edges, and five land portions divided by the circumferential grooves. The circumferential grooves include an inboard shoulder circumferential groove located nearest to the inboard tread edge in the circumferential grooves. The land portions include an inboard shoulder land portion disposed axially outward of the inboard shoulder circumferential groove and having a ground contact surface with the smallest axial width in the land portions. The inboard shoulder land portion is provided with inboard shoulder lateral grooves and inboard shoulder sipes. The inboard shoulder lateral grooves include inner ends away from the inboard shoulder circumferential groove. The inboard shoulder lateral grooves extend axially outward from the inner ends to a location beyond the inboard tread edge. The inboard shoulder sipes extends from the inboard shoulder circumferential groove to a location beyond the inboard tread edge.
US11801714B2
In a tire 12, a tread 14 includes a tread main body 44 and edge portions 46. A wear resistance index of each edge portion 46 obtained according to JIS K6264-2 is higher than that of the tread main body 44. An outer surface S of the tire 12 includes a tread surface ST, a pair of shoulder surfaces SH connected to the tread surface ST, and a pair of side surfaces SW connected to the shoulder surfaces SH. Each shoulder surface SH includes an outer surface formed by the edge portion 46, and a contour of each shoulder surface SH is represented by a circular arc having a center at an inner side.
US11801711B2
A wheel assembly to be coupled to a hub of a vehicle may include an inner rim to be coupled to the hub of the vehicle and an outer rim surrounding the hub. The wheel assembly may also include gas springs operatively coupled between the inner rim and the outer rim. At least one gas spring may have a controllable operating response.
US11801710B2
A fiber-composite ventilation flap for a vehicle is made of a laminate formed by at least two individual tiers. At least one of the individual tiers has respective unidirectionally oriented fibers, and wherein the at least two individual tiers are arranged in the laminate in such a way that the fibers thereof are oriented at least predominantly differently to one another. The fibers of the at least two individual tiers are oriented differently to one another in such a way that at least one region of the fiber-composite ventilation flap curves about a predefined primary axis under the influence of heat and is thereby in an open state.
US11801703B2
A heat sensitive transfer sheet that achieves high optical density and high light resistance without generating scumming. The heat sensitive sheet has a base material and a coloring material layer formed on the base material, and the coloring material layer includes a compound represented by the following formula (1) and a particular dye compound: wherein R11 and R13 each independently represent a hydrogen atom, an alkyl group, an aralkyl group, an unsubstituted aryl group or an aryl group having a substituent; and R12 and R14 to R18 each independently represent a hydrogen atom or an alkyl group.
US11801702B2
A coating composition for producing a heat-sensitive recording material and to a corresponding heat-sensitive recording layer. The coating composition includes one or more color developers, one or more dye precursors, one or more specific fatty acid amides, and one or more (additional) specific sensitizers. A heat-sensitive recording material including a carrier substrate and a heat-sensitive recording layer, to the use of specific fatty acid amides in order to increase the grease resistance of a heat-sensitive recording material or a heat-sensitive recording layer, and to a method for producing a heat-sensitive recording material or a heat-sensitive recording layer.
US11801700B2
A manufacturing method of decorated natural leather including the steps of: attaching a crusted leather (45) with its corium side by an adhesive (46) to a temporary carrier (47); inkjet printing the crusted leather (45) on its grain side with one or more pigmented inkjet inks; wherein the surface area of the temporary carrier (47) is larger than the surface area of the crusted leather (45).
US11801692B2
A printing device includes a liquid composition having a viscosity of from 2 to 15 mPa·s and a static surface tension of from 20 to 50 mN/m. A liquid composition container contains the liquid composition, a liquid composition applying device is configured to apply the liquid composition to a contact-target member, and a contact member is configured to make contact with a region to which the liquid composition has been applied in the contact-target member. The contact member includes a liquid composition holding layer configured to hold the liquid composition, an adhesive layer that fixes the liquid composition holding layer, and a core, in this order from a side that makes contact with the region. The liquid composition holding layer has a thickness of from 200 to 1,300 μm.
US11801689B2
A method of operating a transfer printer configured to transfer ink from a printer ribbon to a substrate which is transported along a predetermined substrate path adjacent to the printer. The printer comprises a tape drive comprising two tape drive motors, two tape spool supports on which said spools of ribbon may be mounted, each spool being drivable by a respective one of said motors. The printer further comprises a printhead being displaceable towards and away from the predetermined substrate path and being arranged to, during printing, contact one side of the ribbon to press an opposite side of the ribbon into contact with a substrate on the predetermined substrate path, and a printing surface. The printer further comprises a controller configured to control the tape drive to transport ribbon between the first and second ribbon spools. The method comprises controlling the tape drive to perform a ribbon movement in which ribbon is transported between first and second ribbon spools along a ribbon path, the ribbon path having a first length during a first part of said ribbon movement, and a second length during a second part of said ribbon movement, a transition from the first length to the second length being caused by a displacement of the printhead with respect to the printing surface, wherein control of at least one of the tape drive motors is based upon data indicative of the first and second lengths.
US11801688B2
A recording control device. A first portion control section forms a first portion as a portion that is continuous from a first region and is not continuous to a second region in a recording region in an output image that is formed on a medium in an overlapping region in a recording region, in such a manner that a use rate of a first nozzle row of an overlapping portion of a nozzle row is set to a first nozzle use rate. A second portion control section forms a second portion as a portion that is continuous with the first region and the second region in the output image in the overlapping region, in such a manner that the use rate of the first nozzle row of the overlapping portion is set to the second nozzle use rate.
US11801681B2
A dispensable substance container may include a printing substance dispensing nozzle including a first material. The dispensable substance container an elongate body, including a wall, including a second material encompassing a cavity to contain a dispensable substance, and an attachment portion to attach the elongate body to the printing substance dispensing nozzle; and a structurally compromised portion of the elongate body extending along a length of the elongate body, wherein the elongate body and the attachment portion are to be severed along the structurally compromised portion by a pushrod moveable through the cavity to expel the dispensable substance out the dispensing nozzle.
US11801679B2
An image forming apparatus includes a recording head, a cap, a tank, a pump, a third communication pipe and a controller. The cap forms a sealed space including an ejection port of the recording head. The tank is connected to the sealed space through a first communication pipe and generates a humidified air. The pump feeds the humidified air to the sealed space through the first communication pipe. The third communication pipe connects the pump and the sealed space. The controller is performable a capping operation to feed the humidified air to the sealed space and a long-period leaving operation to feed the humidifying liquid in the tank to the sealed space through the third communication pipe and to stop a driving of the pump after a predetermined amount of the humidifying liquid is fed in the sealed space.
US11801678B2
A piezoelectric device includes a substrate, a diaphragm; and a piezoelectric actuator, in which the substrate, the diaphragm, and the piezoelectric actuator are laminated in this order in a first direction, the diaphragm includes a first layer containing silicon as a constituent element, a third layer disposed between the first layer and the piezoelectric actuator and containing zirconium as a constituent element, and a second layer disposed between the first layer and the third layer and containing at least one impurity element selected from the group consisting of a metal, a metalloid, and a semiconductor other than silicon and zirconium, as a constituent element, and the impurity element diffuses into the third layer.
US11801677B2
Printheads and design of printheads. In one embodiment, a printhead comprises a plurality of jetting channels, and a manifold apparatus fluidly coupled to the jetting channels. For each jetting channel, the printhead includes a first fluid path between the jetting channel and the manifold apparatus, and a second fluid path between the jetting channel and the manifold apparatus. The jetting channel is configured to jet a print fluid via pressure waves generated in a pressure chamber of the jetting channel. Lengths of the first fluid path and the second fluid path are different by a threshold length so that an arrival time of the pressure waves at the manifold apparatus are different by a threshold time.
US11801674B2
An optical gloss meter above an imaging member surface measures fountain solution surface gloss on the imaging member surface in real-time during a printing operation. The measured gloss corresponds to a thickness of the fountain solution layer and may be used in a feedback loop to actively control fountain solution layer thickness by adjusting the volumetric feed rate of fountain solution added onto the imaging member surface during a printing operation to reach a desired uniform thickness for the printing. This fountain solution monitoring system may be fully automated.
US11801670B2
A squeezable, white polypropylene film is disclosed having a novel balance of conformability, stiffness, modulus, opacity, and whiteness. The film includes an ABCBA structure having a core layer of polypropylene resin with an elastomeric copolymer and a cavitating agent. Two intermediate layers of polypropylene resin are present on either side, the intermediate layers optionally including an elastomeric copolymer and a pigmenting agent. Two polymer skin layers surround the two intermediate layers. The resins are co-extruded into a biaxially oriented film having a thickness between 40 to 70 pm for use in pressure-sensitive labeling applications.
US11801663B2
The invention relates to a method for producing a steel composite in which at least two steel sheets that consist of different steel grades are placed against each other, hot rolled together, and then possibly cold rolled and in which after the rolling, the composite material, which is thus produced from at least two layers with different steel compositions, is diffusion annealed, wherein the annealing temperature is set so as to select the chemical potential of the steel materials to correspond to the following equation: μC,material 1>μC,material 2, where material 1 has a lower carbon content than material 2 so that an uphill diffusion of carbon takes place between material 1 and material 2.
US11801660B2
A laminated acoustic absorption member that includes at least a first fiber layer and a second fiber layer, as well as at least one substrate layer present between the first fiber layer and the second fiber layer, wherein: the first fiber layer has an average flow pore diameter of 0.5-10 μm and a basis weight of 0.1-200 g/m2; the second fiber layer has an average flow pore diameter of 0.5-10 μm, the average flow pore diameter of the second fiber layer being equal to or less than that of the first fiber layer, and also has a basis weight of 0.1-200 g/m2; the substrate layer has an air permeability of 40 cc/cm2·s or greater as measured by the Frazier method, and a basis weight of 1-700 g/m2; and the first fiber layer and the second fiber layer are disposed on a sound-incidence side and a sound-transmission side, respectively.
US11801656B2
There is provided a laminated composite structure having improved impact damage resistance and improved strength. The laminated composite structure has a plurality of stacked layers of a composite material. The plurality of stacked layers have one or more interlaminar corrugations formed within the plurality of stacked layers. Each interlaminar corrugation has a substantially sinusoidal shaped profile, and has a depth and a length dependent on a size of the laminated composite structure formed. The laminated composite structure with the one or more interlaminar corrugations has improved strength and improved impact damage resistance at an exposed edge of the laminated composite structure, when the exposed edge is subjected to an impact force.
US11801644B2
A method of three-dimensional fabrication of an object is disclosed. The method comprises: forming a plurality of layers in a configured pattern corresponding to the shape of the three-dimensional object, at least one layer of the plurality of layers being formed at a predetermined and different thickness selected so as to compensate for post-formation shrinkage of the layer along a vertical direction. In various exemplary embodiments of the invention spread of building material of one or more layers is diluted at least locally such as to maintain a predetermined thickness and a predetermined planar resolution for the layer.
US11801641B2
A shaping apparatus, a shaping method, and a shaping program with which a shaped object can be formed to have the interior with excellent color expression are provided. A 3D printer forms a three-dimensional shaped object having an interior colored, with layer bodies of a light reflective material and a coloring material ejected from an ejection head based on color image data layered. The 3D printer determines arrangement positions of a light reflective material and a coloring material so that the light reflective material is arranged at a predetermined position in each unit volume in a region to be colored inside a shaped object and the coloring material is arranged around the light reflective material based on the color image data. A set position of the unit volume is set to make one surface of one unit volume come into contact with a plurality of other unit volumes.
US11801633B2
The present disclosure generally relates to additive manufacturing systems and methods involving a mechanism for feeding in a desired amount of fresh recoater blade. This can be accomplished by, for example, spooling the fresh blade material from a spool. This helps prevent work stoppage when a portion of a recoater blade becomes damaged. As such, the present disclosure also relates to a system and method for detecting whether a recoater blade is damaged, and if there is damage, then causing a fresh blade portion to be fed in.
US11801624B2
Arrays of male fastener elements are formed by molding preforms in cavities defined in one or more adjacent plates and shaped to mold preform arms that extend to a plate side, such as in a cross-machine direction of a continuous molding process. The preforms may be deformed to flatten their upper surfaces and lengthen the arms. Stems of preforms have molded side surfaces and each have width, measured in the longitudinal direction of the strip, that narrows with distance from the strip surface, and also narrows with distance from a parting line extending from the strip surface to the head between the arms.
US11801622B2
A retaining wall block having a false joint and a system of retaining wall blocks. The retaining wall block includes a body having a first textured surface and a second textured surface and a false joint dividing the first and second textured surface. The false joint can have a depth divided by the width greater than two inches. The false joint can have an interior angle of less than ten degrees. The system includes a plurality of retaining wall blocks and a first course of retaining wall blocks engaged with a second course of retaining wall blocks below. Each block in the system comprising a front face having a first textured surface and a second textured surface and a false joint dividing the first and second textured surface. The false joint can extend a predetermined depth of a third surface.
US11801620B2
An automatic plant for cleaning moulds for tyres, wherein the moulds are constituted of sectors and cheeks, includes an apparatus for internal cleaning of sectors and cheeks and an apparatus for external cleaning of sectors and cheeks. The apparatus for internal cleaning of sectors and cheeks comprises fixing means for sectors and cheeks in a stable treatment position, a generating device for generating ultrasonic vibrations, transmitting means for transmitting the vibrations from the device to the sector or cheek treated, in such a way as to carry out cleaning of sectors or cheeks by subjecting them to vibrations.
US11801618B2
In a method for producing an implant from a biocompatible silicone, a 3D mathematical model of an implant to be produced is used to create a 3D model of a casting mold for the implant as a negative. The casting mold is produced from a polymeric material through an additive manufacturing process and coated through vapor deposition of a coating material from the parylene family at least in a region that comes into contact with the biocompatible silicone to be cast. A platinum-catalyzed 2-component thermosetting silicone as the biocompatible silicone for the implant is introduced into a mold cavity of the coated casting mold, with a residence time of the implant in a patient's body of more than 29 days. The casting mold is heated to vulcanize the biocompatible silicone, and after cooling down the vulcanized implant is demolded from the casting mold.
US11801610B2
Artificial intelligence based systems and methods are described for analyzing pixel data of an image of a user's body for determining a hair growth direction value of the user's hair. An example method includes aggregating a plurality of training images of a plurality of users' bodies, and training a hair growth direction model operable to output a hair growth direction value. The example method may further include receiving an image of a user comprising pixel data of a portion of the user's body or body area, and analyzing, by the hair growth direction model, the image to determine a user-specific hair growth direction value of the user's hair. The example method may further include generating a product recommendation, wherein the product is designed to address a feature identifiable within the pixel data of the user's body or body area.
US11801599B2
A method for designing a customized robot to perform a specified function begins by initially creating an electronic library of data about modules and accessories for a robot assembly. The library stores, for each module and accessory, at least firmware for operation and dimensions. Per robot, the method includes receiving a set of functions and requirements of the customized robot, generating design(s) for the customized robot by finding a set of modules or accessories which match at least one of its functions and requirements, based on information in the electronic library, performing a set of validation tests of each design against criteria, identifying the design(s) which passed the set of validation tests, and generating a list of modules and accessories of a selected design and a connection map for the selected design indicating how the modules and accessories are to be connected together to form the customized robot.
US11801598B2
A substrate transport apparatus including a frame, a drive section connected to the frame and including at least one independently controllable motor, at least two substrate transport arms connected to the frame and comprising arm links arranged for supporting and transporting substrates, and a mechanical motion switch coupled to the at least one independently controllable motor and the at least two substrate transport arms for effecting the extension and retraction of one of the at least two substrate transport arms while the other one of the at least two substrate transport arms remains in a substantially retracted configuration.
US11801594B2
A power tool includes a side handle that can be toollessly positioned and also attached to or detached from a tool body. The power tool includes a tool body having a side surface, a side handle on the side surface of the tool body, and an operable portion operable to attach or detach the side handle to or from the tool body and to position the side handle being attached to the tool body.
US11801592B1
Rail hammer assemblies suitable for advancing driving a member into or toward or pulling a member from or away from a workpiece, respectively may include an impact mechanism. The impact mechanism may include an elongated slide rail. A first rail impact plate may be carried by the slide rail. A second rail impact plate may be carried by the slide rail in spaced-apart relationship to the first rail impact plate. At least a first permanent magnet may be carried by the slide rail outside the first rail impact plate. At least a second permanent magnet may be carried by the slide rail outside the second rail impact plate. An impact hammer may be slidably carried by the slide rail between the first rail impact plate and the second rail impact plate. The impact hammer may include at least one electromagnet. A control system may include at least one power source. A first button may interface with the at least one power source and the electromagnet to facilitate travel of the impact hammer in a first direction on the slide rail. A second button may interface with the at least one power source and the electromagnet to facilitate travel of the impact hammer in a second direction on the slide rail. Rail hammer methods are also disclosed.
US11801590B2
A fastener driver includes a pusher assembly slidably coupled to a magazine assembly. The pusher assembly includes a first portion and a second portion that are selectively movable relative to each other. The pusher assembly is adjustable between a first state in which the first portion and the second portion are configured to move together in unison toward the channel, and a second state in which the first portion moves relative to the second portion toward the channel. A dry-fire lockout assembly includes a blocking member coupled to the magazine assembly or the nosepiece assembly, and a lockout member selectively engageable with the blocking member for moving the blocking member from a first position and a second position. The pusher assembly is configured to transition from the first state to the second state after a predetermined number of fasteners remain in the magazine assembly.
US11801586B2
A system for laser processing includes a plate assembly having a first plate, a second plate secured to the first plate, and a pressure chamber located between the plates, a connector extending into and in fluid communication with the pressure chamber, and a fixture having a first end attached to the second plate of the plate assembly, a second end having surface having at least one opening and shaped to fit a part to be retained and laser processed, and a conduit extending therethrough in fluid communication with the pressure chamber and the at least one opening. During use, a pressure generated by a pump may be communicated to the conduit of the fixture through the pressure chamber to provide pressure (e.g., a suction effect) at the opening(s) to secure the part in place, e.g., with respect to another part, so they can be laser processed.
US11801580B1
An apparatus for rotating a seat relative to ball in a valve lapping machine includes a seat spindle assembly, an airbag assembly with a first and a second airbag, and a linear compensator affixed to a frame of the seat spindle assembly and to the seat tooling adapter plate. The airbag assembly is adapted to apply contact force between the seat and the ball. The linear compensator has a top plate, middle plate and a bottom plate. A first set of rails extends in a first direction so as to allow movement between the top plate and the middle plate, while a second set of rails which extends in a second direction perpendicular to the first direction allow movement of the bottom plate relative to the middle plate. A ball valve lapping machine utilizing this apparatus is also provided.
US11801573B2
A tack welding method and a tack welding apparatus that can improve the strength of a tack-welded joint portion and reduce the height of a reinforcement bead is provided. A tack welding method of the present embodiment is a tack welding method of tack-welding a part of a joint portion of a first joint and a second joint at a predetermined interval before main welding. In the tack welding method, a filler metal is supplied to the joint portion, laser light is deflected and irradiated to the joint portion, and the filler metal is cut with the laser light to be welded to the joint portion.
US11801571B2
A laser processing device for processing shielded conductors includes a processing chamber configured to process an end portion of a shielded conductor disposed therein using laser radiation. The processing chamber has a housing defining an opening. In a processing position of the laser processing device, the end portion of the shielded conductor is inserted along an insertion axis into the opening and extends into the processing chamber. A gripping device is configured to fix the shielded conductor in the opening in the processing position of the laser processing device. In the processing position of the laser processing device, the gripping device is positioned at the housing without contact therebetween. The gripping device includes a first projection portion which extends at least partially into the opening along the insertion axis in the processing position of the laser processing device.
US11801558B2
A three-dimensional PBF-AM apparatus includes a stage on which a powder material is spread, and a tubular build box disposed in a state of surrounding the stage. The build box includes a side wall portion having a first tubular member surrounding the stage and a second tubular member surrounding the stage with the first tubular member interposed therebetween and forming a space with the first tubular member, and moreover, a vacuum heat insulating layer can be formed inside the side wall portion by vacuuming the space.
US11801554B2
An additive manufacturing method includes cold spraying a powder onto a build area to create a densified powder layer. The method can include high speed machining the densified powder layer after cold spraying to create a smooth layer.
US11801553B1
The method for making carbon-coated copper nanoparticles is a simple, one-step for coating copper nanoparticles with a carbon shell to prevent rapid oxidation of the carbon nanoparticle core. The method involves heating or autoclaving thin sheets of copper hydroxide nitrate (Cu2(OH)3NO3) under supercritical conditions (a temperature of 300° C. and a pressure of 120 bar) for two hours. The autoclaving may be performed in the presence of an inert gas, such as argon, which may be used to remove any remaining gases, and the pressure may be released in the presence of the inert gas so that the product may be collected in the presence of air.
US11801552B2
Disclosed is a device for continuous treatment of materials containing volatile components, which belongs to the field of pyrometallurgical equipment. The device includes a feeding unit, a heating unit, a slag raking unit and a slag collecting unit. The feeding unit is configured to feed the materials with a push rod or in a spiral mode. The heating unit is provided with a square furnace body, and a first slag raking port is provided in the lower part of the furnace body. The slag collecting unit is provided with a slag discharging port at the lower portion thereof, is provided with a slag smashing port at the sidewall thereof, and is provided with a viewing port at the top thereof. The slag collecting unit and the heating unit are connected through a pipeline, thus achieving the pressure balance of the whole device during operation.
US11801549B2
A method for removing a blind rivet includes a workpiece arrangement having first and second surfaces and a connecting hole. A blind rivet is fixed in the hole and has a shell and screw through the shell extending coaxially along a common center axis, the shell having a shell head portion, straight portion, deformation portion and threaded portion having an internal thread. The straight portion is in the hole and the deformation portion and the threaded portion protrude out of the hole, the screw having a screw head portion and pin portion having an external thread. The screw is in the shell such that the deformation portion of the shell is deformed where the outside diameter of the deformed deformation portion is larger than the diameter of the hole. The shell is cut in the region of the thread portion and/or the deformation portion, and the blind rivet is removed from the hole.
US11801530B2
Disclosed is a tea leaf and tea stem separating device. The tea leaf and tea stem separating device comprises a machine shell, wherein a collecting mechanism, a peeling mechanism, a separating mechanism, a rocker mechanism and recycling mechanisms are sequentially arranged on the machine shell in the falling direction of materials, a driving mechanism is arranged at the position, corresponding to the separating mechanism, of the inner wall of the machine shell, the driving mechanism is provided with a conveyor belt mechanism connected with the peeling mechanism, the separating mechanism and the rocker mechanism, and the driving mechanism can drive the conveyor belt mechanism to move so as to pull the peeling mechanism, the separating mechanism and the rocker mechanism to synchronously reciprocate.
US11801528B2
The present application provides stable, carbene-functionalized composite materials, and methods and uses thereof. These carbene-functionalized composite materials comprise a material having a metal surface, and a carbene monolayer that is uniform, contaminant-free (metal oxide, etc), and more stable than thiol-functionalized monolayers. Uses of such carbene-functionalized composite materials include semi-conducting materials, microelectronic devices, drug delivery or sensing applications.
US11801527B2
A nozzle applies a sealant to a target area that includes a coupling member and an elongated seam. The nozzle includes a primary portion positionable in line with the coupling member in the target area, a first secondary portion on a first side of the primary portion, and a second secondary portion on a second side of the primary portion. The primary portion is in fluid communication with one or more material sources. The first secondary portion extends from the primary portion such that the first secondary portion is configured to extend over at least a segment of the elongated seam in the target area when the primary portion is positioned in line with the coupling member in the target area. The first secondary portion has a first height, and the second secondary portion has a second height less than the first height.
US11801526B2
A method of coating a fastener assembly that extends from a substrate comprises steps of at least partially saturating a permeable body with a volume of a liquid and covering the fastener assembly with the permeable body. The step of covering the fastener assembly with the permeable body comprises at least partially compressing the permeable body against the fastener assembly and transferring a portion of the volume of the liquid from the permeable body to an exposed outer surface of the fastener assembly and to a ring on the substrate, surrounding the fastener assembly.
US11801524B2
A device for dispensing a fluid substance includes a manually operated pump with a hollow stem movable counter to a spring, the hollow stem coupled with a piston which slides in a sealed manner inside a cup body to define a compression chamber coupled with a first valve element for the inlet of the fluid substance into the compression chamber fluidly coupled with a second valve element for the outlet of the fluid substance from the compression chamber, there being a dispensing button equipped with a dispensing nozzle mounted on the hollow stem, the dispensing button featuring at least one channel for supplying the fluid substance to the nozzle; the nozzle is formed of an essentially rigid body which is secured, in a sealed manner, into a seat in the dispenser button, the rigid body being coupled with a deformable body defining a dispensing port so that during dispensing, the deformable body—at least in the vicinity of the dispensing port—deforms and then returns to its non-deformed configuration thereafter.
US11801522B2
A double tentacle pump system for a liquid sprayer includes first and second tentacle pumps positioned serially within a flow path that extends between a liquid container and the outlet of the sprayer. A motor is configured to actuate the first and second tentacle motors in response to a user directed trigger, thereby causing fluid to be moved from the container and expelled from the sprayer.
US11801518B1
The disclosure relates to methods, systems and compositions for use in the harvesting of nectar from plants or their portions. More specifically, the disclosure relates to systems, compositions and methods for semi-continuously harvesting nectar from plants or their portions having extrafloral nectaries (EFN) with augmented nectar production.
US11801512B2
A dispersant system comprises a plurality of taggant vessels, each having a taggant that corresponds to a position in a tag string and a computer controller convert the tag string into a selection of a taggant set while computer-controlled valves allow or block a flow of taggants to a manifold output tube. From the output tube, a mix of the taggants flow to form a dispersant formed according to the tag string. A nozzle disperses the dispersant onto an object to be tagged, possibly atomized with air. The taggant can comprise a DNA taggant comprising a static portion and a dynamic portion that is unique to each tag string position. Tag strings for adjacent lots might have a low Hamming distances to reduce cross-contamination and/or have redundancy for error detection and correction and selected so that consumption of taggants evens out over the plurality of taggant vessels.
US11801511B2
Provided herein is technology relating to collecting and containing samples and particularly, but not exclusively, to technology for collecting and containing a stool specimen. The technology provides a device for collecting and containing a stool specimen, the device comprising ergonomic features optimized for a geriatric user. The technology also provides an enclosing holder for securing the ergonomic stool specimen container in a leak-proof manner e.g., during mechanical shaking.
US11801508B2
In biosciences and related fields, it can be useful to modify surfaces of apparatuses, devices, and materials that contact biomaterials such as biomolecules and biological micro-objects. Described herein are surface modifying and surface functionalizing reagents, preparation thereof, and methods for modifying surfaces to provide improved or altered performance with biomaterials.
US11801507B2
The present invention is a cuvette assembly for use in optically measuring at least one characteristic of particles within a plurality of liquid samples. The cuvette assembly comprises a main body having internal walls and external walls, and a plurality of cuvettes within the main body at least partially being defined by the internal walls. Each of the plurality of cuvettes has a liquid-input chamber for receiving a respective one of the plurality of liquid samples, a filter, and an optical chamber for receiving a respective filtered liquid sample caused by passing the respective one of the plurality of liquid samples through the filter. Each of the optical chambers includes an entry window for allowing transmission of an input light beam through the filtered liquid sample and an exit window for transmitting a forward scatter signal caused by the particles within the filtered liquid sample.
US11801504B2
Provided is a hydrophilic phosphorus ligand with the structure of formula 1. X is Y is m is an integer from 1 to 20, A independently is *—O(CH2)n—, n is an integer from 1 to 5, *— is a bond close to triphenylphosphine, and — is a bond away from triphenylphosphine.
US11801503B2
A process of manufacture of a solid catalyst made of a support coated with a thin catalytic layer and a process for eliminating gaseous and/or particulate pollutants in an exhaust gas. The process of manufacture includes preparing a solution A by dissolving alkoxide and/or chloride precursors of at least one metal selected from Al, Si, Ti, Zr, Fe, Zn, Nb, V and Ce in a solvent S1, preparing a solution B containing a surfactant, an organic acid, and/or hydrochloric acid (HCl) in a solvent S2, mixing solution A and solution B together, thereby obtaining a washcoat solution C, and dip-coating, drying, and calcinating the support into washcoat solution C. The processes provide for elimination of volatile organic compounds (VOCs), CO, and/or particulate pollutants in an exhaust gas.
US11801496B2
The present disclosure relates to a catalyst for preparing 1,2-pentanediol from furfural and/or furfuryl alcohol, and more particularly to a catalyst, which is configured such that a catalytically active metal containing both at least one transition metal and tin (Sn) is supported on a basic support and is capable of increasing reaction selectivity for 1,2-pentanediol, and a method of preparing 1,2-pentanediol using the same.
US11801487B2
Systems and methods for generating a brine solution using a salt bag for recharging zirconium phosphate in a reusable sorbent module are provided. The salt bag can be a double layer bag. An inner water permeable bag can contain solid salts and can be surrounded by an outer water impermeable bag. Water can be added to dissolve the salts in the inner bag and the resulting solution can be collected as a brine solution for use in recharging the zirconium phosphate.
US11801484B2
A food recycler can include a mixing bin defining a mixing chamber having a first inlet and a first outlet. A stirrer has a stirrer drive shaft and at least one blade coupled to the stirrer drive shaft and located within the mixing chamber. An output bin defines an output chamber having a second inlet operably coupled to the first outlet and a second outlet.
US11801482B2
Methods and apparatus are disclosed relating to mixing fluids in welding-type equipment. In some examples, a welding-type power supply (and/or wire feeder) may include multiple fluid paths through which to provide fluid from multiple fluid reservoirs to multiple welding-type tools. The power supply may be configured to automatically control fluid flow rates through the fluid paths via proportional valves. Further, the welding-type power supply may be configured to allow and/or prohibit mixing of fluids from different flow paths via control of various valves.
US11801480B2
A hollow-fiber membrane according to an aspect of the present disclosure contains a polytetrafluoroethylene or a modified polytetrafluoroethylene as a main component and has an average outer diameter of 1 mm or less and an average inner diameter of 0.5 mm or less. In a measurement of a heat of fusion of the polytetrafluoroethylene or the modified polytetrafluoroethylene with a differential scanning calorimeter, when the polytetrafluoroethylene or modified polytetrafluoroethylene is subjected to a first step of heating from room temperature to 365° C., a second step of cooling from 365° C. to 350° C., maintaining the temperature, subsequently cooling from 350° C. to 330° C., and further cooling from 330° C. to 305° C., and a third step of cooling from 305° C. to 245° C. at a rate of −50° C./min and subsequently heating from 245° C. to 365° C. at a rate of 10° C./min, a heat of fusion from 296° C. to 343° C. in the third step is 30.0 J/g or more and 45.0 J/g or less.
US11801479B2
Disclosed is a method of improving the effectiveness of an oxygen removal unit for a fuel supply system. The method includes contacting a tube bundle with a repair liquid at 20 to 40° C. for less than two hours. The tube bundle includes tubes having an air permeable, non-porous polymer layer with discontinuities. The repair liquid includes a solvent and a curable thermoset material. The curable thermoset material is deposited in the discontinuities of the air permeable, non-porous polymer layer and cured. Also disclosed is a fuel system oxygen removal unit including a tubular bundle formed of tubes having an air permeable, non-porous polymer layer disposed on a microporous support wherein the air permeable, non-porous polymer layer includes discrete segments of a cured thermoset material.
US11801477B2
A cell retention device includes a structured support with a plurality of circumferentially distributed ribs to retain the active filtering surface of a flexible, porous membrane filter medium. The filter medium surrounds the support in contact with the peaks of the ribs, thereby forming axial voids between the rib peaks. This arrangement imparts sufficient structural support over small regions of the filter medium to facilitate its use in a circular (or other rounded) configuration while providing sufficient channel volume to support high throughput of fluid sparse of cells.
US11801476B2
An efficient low-energy carbon dioxide removal system comprises an automated air mover equipped with sensing devices to measure flow rate, volume, level, pressure, temperature and concentration. Packing materials and air-liquid distributors are used in a multi-stage catalytic reactor. The multi-stage catalytic reactor processes ambient air and generates pure carbon dioxide gas and generates exhausted gas released to ambient air. In operation, air contacts the base solution in the presence of a catalyst via the air mover, distributor, and packing materials. The air reacts with the base solution thereby generating a base solution having carbon dioxide and generating exhaust (absorption reaction). Next, the exhaust is released from the reactor. Next, a catalyst is added, heat is applied to the base solution having carbon dioxide thereby generating carbon dioxide and generating a base solution without carbon dioxide (desorption reaction).
US11801472B2
Certain implementations of amine sweetening of flash gas are described. Flash gas including acid gas is flowed from a flash drum through a column section connected to the flash drum. A lean amine stream is flowed through the column section. The lean amine stream is configured to treat the acid gas flowed from the flash drum through the column section. A quantity of the lean amine stream flowed through the column section is controlled based, in part, on a rate at which the flash gas including the acid gas is flowed from the flash drum through the column section and a concentration of the acid gas in the flash gas.
US11801471B1
A support frame apparatus for a thermal fluid includes: a support frame adapted to be coupled to an inner wall of an adsorption device, and defining a chamber therein, a first channel for accommodating the thermal fluid being formed in a wall of the support frame, and a plurality of first holes being formed in the wall of the support frame and being opened to the chamber to spray the thermal fluid into the chamber; and a plurality of support arms disposed within the chamber and each having a first end coupled to the support frame and a second end extended inwardly from the support frame, the support arm defining a second channel therein fluid communicated to the first channel, and the support arm having a plurality of second holes communicated to the second channel and opened to the chamber to spray the thermal fluid into the chamber.
US11801462B2
Filter elements and filter systems are provided. The filter element allows for a reversed flow of fluid through the filter element when flowing from a first port to a second port of a filter head of the filter system. The filter element includes a standpipe in a central cavity of a tube of filter media that is fluidly connected with an exterior of the tube of filter media by a radial flow conduit and an axial flow tube.
US11801456B2
A system for preparing solutions for chromatography application is disclosed. The system comprises a T-joint for preparing a buffer solution by mixing at least one first solution and a second solution. The T-joint receives the second solution from a solution supply unit connected to the T-joint. Further one or more low pressure pumps supply the one or more first solutions into the T-joint. The high pressure pump collects the buffer solution and delivers it to a chromatography apparatus.
US11801450B2
A bubble maker includes a pressurized container; a liquid storage bag; a bubble generator; and a drainage tube connecting the liquid storage bag and the bubble generator. The liquid storage bag is configured to store a bubble solution. The drainage tube is configured to convey the bubble solution to the bubble generator; and the bubble generator is configured to convert the bubble solution into bubbles. The liquid storage bag includes elastic material and is disposed in the pressurized container. The pressured container includes a fluid inlet so that a fluid is introduced to the pressured container via the fluid inlet to squeeze the liquid storage bag, and thus the bubble solution in the liquid storage bag is squeezed into the bubble generator via the drainage tube.
US11801449B2
Methods for hosting low-latency streaming interactive audio/video (A/V) include executing one or more video games or applications on a server communicatively coupled to a data network. Packet streams are received from a plurality of users and routed to the one or more video games. The packet streams include user control input that are used to compute A/V data in response. The A/V data are received from the video games or applications. Portions of the A/V data are compressed in parallel using processing units resulting in low-latency streaming compressed A/V data. The low-latency streaming compressed A/V data are routed to each of the users over a corresponding data network communication channel. The executing of video games, receiving of packet streams and A/V data, compressing portions of the A/V data and routing the compressed A/V data are performed with a latency such that at least one user has the perception that the controlled video game is responding instantly.
US11801448B1
A computerized method and processing system provides for transposing virtual content items between computing environments. The method and system includes receiving a transpose request to transpose a first item from the first computing environment to a second computing environment, including first item data relating to the first item. The method and system includes accessing a plurality of transpose rules relating to transposing the first item to the second computing environment and accessing environment data relating to the first computing environment and the second computing environment. The method and system includes determining a second item for utilization in the second computing environment, a virtual translation of the first item based on the transpose rules and the second computing environment data. The method and system includes transmitting an authorization command to the second computing environment to authorize utilization of the second item in the second computing environment.
US11801447B1
A cross-era sports game system that involves current and historical players, trading cards, stats, and fantasy sports, and is configured to tie fantasy play to physical trading card or token player assets through substitutions or live game play is disclosed. The cross-era sports game system provides a manual or digital sports game everyone can play using historical players, trading cards, stats and fantasy sports.
US11801443B2
One embodiment of a computer-implemented method for generating mouse sensitivity recommendations includes generating mouse movement data corresponding to one or more mouse movements performed by a user while interacting with a software application; generating a predicted efficiency for each mouse sensitivity level included in a plurality of mouse sensitivity levels based on the mouse movement data; and determining one or more mouse sensitivity levels to provide to the user based on the predicted efficiencies.
US11801433B2
A golf instruction method, apparatus and analytics platform for determining the state of a putted golf ball relative to a target using information about the golf ball and external variables and remotely displaying the same comprising a base unit, a mobile device or terminal, and an associated computer program including an analytics engine for analyzing a user's performance. The computer program determines whether and how a putted golf ball has missed said target and then stores, aggregates and displays that information for a user. The analytics engine is operable to aggregate data, analyze data and then correlate a user's actual skill proficiency to ball performance.
US11801430B2
A system for measuring rigidity characteristics that measures a CT value of a golf club head based on an acceleration occurring in an impactor when the impactor is caused to strike the golf club head. Correlation data is calculated by measuring a representative CT value of the golf club head, which is calculated based on CT values measured multiple times by changing the impact velocity of the impactor, and a test velocity CT value, which is a CT value when the impact velocity is set to a predetermined test velocity, for each of a plurality of the golf club heads of an identical model. A rigidity characteristic value measuring device measures the test velocity CT value for another golf club head of the model. A computer estimates the representative CT value of the other golf club head based on the test velocity CT value and the correlation data.
US11801420B2
There is provided a treadmill deck (10) for supporting at least part of a treadmill belt, the deck (10) including a foot strike area (12) disposed towards one end of the deck, and a foot take-off area (14) disposed towards another end of the deck, an upper surface of one of the areas (12, 14) including: a lateral inward or outward slope, which provides a lateral gradient across at least part of the area (12, 14), and an upper surface of the other of the areas (14, 12) including one of: a laterally horizontal surface or a lateral inward or outward slope, which provides a lateral gradient across at least part of that other area (14, 12).
US11801419B2
A system, method and apparatus for exercise and rehabilitation includes a frame coupled to a base and having a top end. An arm having a proximal end can be coupled to the top end of the frame. A distal end of the arm is opposite the proximal end. The arm is movable in a first degree of freedom between a retracted position and an extended position relative to the frame. Handles are coupled to the arm adjacent the distal end and movable in a second degree of freedom relative to the arm. The handles are manipulated by a user for exercise and rehabilitation.
US11801413B2
A weighted bag having an outer shell and a handle assembly. The outer shell has a plurality of panels and at least one of one of a pair of slots and a first end loop assembly and a second end loop assembly spaced apart from the first end loop assembly coupled to the plurality of panels. The handle assembly has a handle grasping member and a strapping assembly, the strapping assembly extending from the handle grasping member and interfacing with at least one of the pair of slots and the first and second end loop assemblies so as to couple the handle assembly to the outer shell.
US11801411B2
The training device is made in the form of a rigid arcuate element that has a central portion and two side portions ending in free ends. The arcuate element comprises rectilinear segments connected to each other at different angles, and it contains at least four rectilinear segments on the side portions thereof.
US11801409B1
A combined double buckle and bungee cord connecting structure for a trampoline is provided. The combined double buckle and bungee cord connecting structure for a trampoline includes a trampoline frame; an edge-folded round steel connected to an inner side of the trampoline frame; anti-friction bearings connected to the edge-folded round steel equidistantly and rotatably; and bungee cords. The trampoline frame is one of a round shape, a hexagonal shape, and a square shape. The edge-folded round steel is connected to the inner side of the trampoline frame by either welding or riveting. The anti-friction bearings are made of one of a plastic, a metal, and a chemical fiber. The bungee cords each are either a round bungee cord or a flat bungee cord. Therefore, the structure effectively reduces the abrasion of the bungee cords in use and can greatly prolong the service lives of the bungee cords.
US11801405B2
A mounting device includes a first arm, a second arm positioned parallel to the first arm, and a top plate coupled to the first arm and the second arm. The top plate includes a center portion, a first coupling panel formed at a 90 degree angle with respect to a surface of the center portion, and a second coupling panel formed at a 90 degree angle with respect to a surface of the center portion. The second coupling panel is located at a side of the center portion opposite the first coupling panel.
US11801394B1
A method for covertly creating adverse health effects in a human subject includes generating at least one electromagnetic wave at a frequency within the range of about 300 MHz (megahertz) and about 300 GHz (gigahertz). The at least one electromagnetic energy wave is pulsed at a pulse frequency within a target range of human neural oscillations. At least one ultrasonic audio wave is generated at a frequency greater than about 20 kHz (kilohertz). The at least one audio wave is pulsed at the pulse frequency. Each of the at least one pulsed electromagnetic wave and the at least one ultrasonic audio wave are remotely transmitted to the subject's brain.
US11801391B2
Implantable medical devices (IMDs) described herein, and methods for use therewith described herein, reduce how often an IMD accepts a false message and/or reduce adverse effects of an IMD accepting a false message. Such IMDs can be leadless pacemakers (LPs), or implantable cardio defibrillators (ICDs), but are not limited thereto. Such embodiments can be used help multiple IMDs (e.g., multiple LPs) implanted within a same patient maintain synchronous operation, such as synchronous multi-chamber pacing.
US11801383B2
Neuromodulation devices and methods of their use are described in which a therapeutic device is configured to generate a treatment for treating pain such as the reduction of the symptoms of chronic and acute pain as well as for treating other conditions. The neuromodulation device generates an output electrical signal in the form of pulses with a fast rise-time spike waveform followed by a longer-duration, lower amplitude primary phase waveform. The output signal includes a broad range of frequency components, with time constants tuned so as to interact with specific cell membrane or cellular components. The output signal may be conducted to the patient via electrodes. The pulses are triggered at variable intervals which prevent habituation.
US11801373B1
An insoluble transdermal microneedle patch, includes microneedles and a backing. The microneedles include bases and needlepoints located on the base, and materials made for the microneedles include crosslinked sodium alginate. The backing is connected with the bases, and parts of the backing corresponding to the needlepoints are hollow portions. The microneedle patch can act in the skin for a long time, during it is used for transdermal delivery, drugs can enter skin micropores to be absorbed into a body through pores formed after swelled microneedles acting on the skin absorbs water, thereby increasing a bioavailability of the drugs during the transdermal delivery. After drug administration end, the microneedles are completely removed without increasing a metabolic burden in the body, soluble materials are prevented from being accumulated in the body, and the microneedles have good biological safety. A preparation method of the insoluble transdermal microneedle patch and application thereof are provided.
US11801371B2
There is provided a microneedle device comprising a substrate and a plurality of microneedles projecting from the substrate, the substrate being substantially spherical and wherein in use, the microneedle device has three-dimensional movement. There is also provided a method of forming the microneedle device of the present invention.
US11801363B2
The present disclosure provides a catheter system and methods for use that includes (a) a first catheter having a first end and a second end, where the first catheter has a first diameter, (b) a second catheter having a first end and a second end, where the second catheter has a second diameter that is less than the first diameter of the first catheter, and where the second catheter is positioned at least partially within a lumen of the first catheter and is moveable relative to the first catheter, and (c) a wire having a first end and a second end, where the first end of the wire is coupled to the second catheter.
US11801356B2
The present invention relates to a system (1; 1A) for use in connection with mechanical ventilation of a patient (3), provided by a ventilator (5). The system comprises a sensor arrangement (7; 7A; 7B) configured to register at least one signal (SLP; SLP(TA), SLP(CT); Se1-5; Se11-12), herein referred to as LP signal, related to muscular activity of at least one muscle (17, 19) in the laryngopharyngeal region (9) of said patient (3). Furthermore, the system comprises at least one control unit (11; 11A, 11B) configured to control the operation of said ventilator (5) based on said at least one LP signal, and/or to cause display of information related to said at least one LP signal on a display unit (13A, 13B) for monitoring said patient (3) and/or the operation of the ventilator (5).
US11801351B2
A concentrate adaptor for a vaporizer device includes a reservoir and a base. The reservoir holds a concentrate. The reservoir is positioned within a vessel of the vaporizer device and is heated by a heating element of the vaporizer device to transfer heat to the concentrate, thereby generating an aerosol for inhalation by a user. The reservoir includes a sidewall surrounding an interior volume of the reservoir. The reservoir also includes a capillary structure positioned along the sidewall configured to direct the concentrate to the sidewall to be heated by the heating element.
US11801349B2
Devices and methods for use with syringes are disclosed. A plunger rod includes an outer housing having proximal and distal ends and a lumen between the ends, as well as an inner body axially slidable within the lumen between a first and second position. The inner body has a retention member extending therefrom. When the inner body is in the first position, the plunger rod has a first length, and, when the inner body is in the second position, the plunger rod has a second length greater than the first length. When the inner body is in the second position, the inner body is configured to be rotated relative to the outer housing until the retention member is received within the outer housing to preclude the inner body from moving in the axial direction.
US11801343B2
Certain aspects of the present disclosure provide a surgical system comprising a fluid output device capable of connecting to a syringe comprising a material for delivery to a body part through a cannula connected to the syringe and a controller configured to adjust a pressure of the fluid output to enable a controlled delivery of the material within the syringe at a target flow rate.
US11801341B2
Infusion pump interfaces providing simple and intuitive user experiences. A controller display subsystem for implementing infusion pump interfaces includes a processor, a memory, display logic, keypad I/O, and screen I/O. Display logic can command the processor via the memory to implement desirable displays on screen I/O.
US11801338B2
Embodiments disclosed herein are directed to negative pressure treatment systems and wound dressing systems, apparatuses, and methods that may be used for the treatment of wounds. In particular, some embodiments are directed to improved wound dressings comprising an obscuring layer that may hide fluid contained therein. Some embodiments may further comprise one or more viewing windows disposed therethrough so as to enable monitoring or examination of fluids contained therein.
US11801330B2
Products, processes, compositions, kits, and methods are provided for cartilage-derived implants. The implants can exhibit resistance to enzyme (e.g., collagenase, protease, etc.) digestion compared to the source tissue from which they were derived while still having one or more mechanical properties comparable to the source tissue from which they were derived. The implants can also have a plurality of molecular bridges between molecules of the cartilaginous material. The molecular bridges can connect one or more collagen fibrils and/or/with one or more glycosaminoglycans. The implants can also be treated with cationic detergent, packaged and sterilized with or without additional components, and surgically implanted into subjects.
US11801323B2
A lotion composition is provided. The lotion composition includes a) about 1% to about 90%, by weight, of a rheology structurant; and a b) carrier.
US11801321B2
The Scented Decorative Plunger Holder is a canister for holding a plunger. The holder has a lid and body. The lid has a portion configured to contain a scented agent, and this portion is magnetically connected to the lid. The lid and body have vents. The Scented Decorative Plunger Holder, can be made in a variety of styles using any color or a multi-color design.
US11801319B2
Systems and methods for the construction of a disinfection and/or sanitizing device that provides for individual users the ability to disinfect utilizing ultraviolet (UV) light. The device is designed to be in the form of a tool that can attach to and be readily carried in conjunction with a smart device such as a smartphone and to utilize the battery of the smart device so that it is unnecessary to obtain separate batteries.
US11801312B2
A method of treating cancerous tumors is presented herein. The method includes injecting an effective dose of a plasmid encoded for IL-12, B7-1 or IL-15 into a cancerous tumor and subsequently administering at least one high voltage, short duration pulse to the tumor. The electroporation pulses may be administered at least 700V/cm for a duration of less than 1 millisecond. The intratumor treatments with electroporation may be administered in at least a two-treatment protocol with the time between treatments being about 7 days. The intratumor treatments with electroporation may be administered in a three-treatment protocol with a time of four days between the first and second treatments and a time of three days between the second and third treatments. It was found that the intratumor treatments using electroporation not only resulted in tumor regression but also induced an immune memory response which prevented the formation of new tumors.
US11801311B2
The present disclosure relates to antisense oligonucleotides (AONs) for modulating the expression of glycogen synthase. AONs of the present disclosure may be useful in treating diseases associated with the modulation of the expression of the enzyme glycogen synthase, such as Pompe disease. Also provided by the present disclosure are compositions comprising AONs, as well as methods of down regulating mRNA coding for glycogen synthase, methods for reducing glycogen synthase in skeletal and cardiac muscle, and methods for treating Pompe disease.
US11801308B2
Disclosed herein is a drug delivery vehicle. The drug delivery vehicle includes a lipid nanoparticle core for enclosing a primary drug and a protective shell surrounding the lipid nanoparticle. Also disclosed herein is a drug delivery system including the drug delivery vehicle carrying the primary drug, a method of preparing the drug delivery system and a method of using the drug delivery system.
US11801305B2
Several embodiments of the present disclosure relate to therapeutic compositions configured to target the liver of a subject and that are useful in the treatment or prevention of one or more of transplant rejection, autoimmune disease, food allergy, and immune response against a therapeutic agent. In several embodiments, the compositions are configured to target the liver and deliver antigens to which tolerance is desired. In several embodiments, the compositions are configured for clearance of a circulating protein or peptide or antibody associated with one or more of the above-mentioned maladies. Methods and uses of the compositions for induction of immune tolerance are also disclosed herein.
US11801291B2
The invention provides methods and compositions for treating fibromyalgia (FM) and chronic fatigue syndrome (CFS) in an individual. The methods provided herein entail administering a composition comprising an isolated Mycobacterium or antigenic fragments derived therefrom. Also provided herein are methods for assessing alleviation of symptoms and/or alteration of immune system functioning following administration of a composition comprising an isolated Mycobacterium or antigenic fragments derived therefrom.
US11801285B2
The present application relates to a compositions and methods comprising or expressing a HEVAR or MOMO30 protein derived from Momordica balsamina. The HEVAR or MOMO30 protein and/or a nucleic acid encoding the same may be used in methods for treating or preventing viral infections, particularly those caused by coronaviruses, such as SARS-CoV-2.
US11801283B2
The invention relates to novel methods, uses and compositions for the prophylaxis or the treatment of osteoarthritis, and conditions associated therewith.
US11801281B2
There is provided a bioabsorbable peptide tissue occluding agent that can be applied to large mammals including humans, the peptide tissue occluding agent being obtained by artificial synthesis to avoid concerns of infection by viruses and the like. The tissue occluding agent contains a peptide, wherein the peptide is an amphiphilic peptide having 8-200 amino acid residues with the hydrophilic amino acids and hydrophobic amino acids alternately bonded, and is a self-assembling peptide exhibiting a β-structure in aqueous solution in the presence of physiological pH and/or a cation.
US11801277B2
The invention discloses synergistic herbal composition comprising combination of first ingredient selected from extracts, fractions, phytochemicals and mixtures thereof derived from Theobroma cacao and a second ingredient selected from extracts, fractions, phytochemical and mixtures thereof derived from Citrus aurantifolia for obtaining at least one health benefit selected from preventing, controlling or treating obesity and/or overweight; improving lean body mass, improving the browning of White Adipose Tissue/improving formation of brown adipose tissue, increasing basal metabolic rate/resting energy expenditure, increasing thermogenesis, improving thyroid function, maintaining healthy body weight, increasing satiety/, supporting weight loss, improving fat loss and maintaining a slim body. The invention further discloses synergistic herbal compositions comprising Theobroma cacao and Citrus aurantifolia and optionally comprises at least one ingredient selected from pharmaceutically acceptable excipient/diluent/carrier; methods of treatment and use for the prevention and treatment of obesity/overweight or improving lean body mass or resting energy expenditure in a human or animal.
US11801276B2
Provided are a microorganism having an ability to degrade ethanol and acetaldehyde, and a composition and a kit each including the microorganism.
US11801272B2
The present invention relates to Bacillus strains which improves health and performance of production animals. The invention further relates to compositions comprising the Bacillus strains.
US11801260B2
Disclosed is a composition for treating a joint disease or a connective tissue disease, a composition for cartilage regeneration, or a composition for treating an inflammatory disease, each of the compositions containing dextran, poloxamer or a mixture thereof. The composition stays in the joint or connective tissue for a long time due to the shock-absorbing effect, coating effect or anti-inflammation effect, relieves the shock, covers a damaged portion in a specific manner thereto, or reduces inflammation of an adhered portion. Thus, the composition may be useful for the treatment of the joint disease, the connective tissue disease, or for the cartilage regeneration.
US11801257B2
A composition and method for activating immune cells ex-vivo, or inducing an immune response in a subject including a composition comprising at least one chiral cationic lipid. The chiral cationic lipid in one embodiment comprises a nonsteroidal cationic lipid having a structure represented by formula (I); wherein in R1 is a quaternary ammonium group, Y1 is a space chosen from a hydrocarbon chain, an ester, a ketone, and a peptide, C* is a chiral carbon, R2 and R3 are independently chosen from a saturated fatty acid, an unsaturated fatty acid, an ester-linked hydrocarbon, phosphor-diesters, and combination thereof.
US11801256B2
A method of enhancing positive effects of a psychedelic, by pretreating an individual with an antidepressant, administering a psychedelic to the individual, and inducing a more positive psychological state in the individual with the antidepressant-psychedelic combination compared with the psychedelic alone. A method of enhancing positive effects of a psychedelic, by inhibiting serotonin transport in an individual, increasing levels of endogenous monoamines in the individual, and stimulating 5-HT2A receptors in the individual. A composition including an antidepressant and a psychedelic in the same dosage form.
US11801255B2
This disclosure relates to lipid disulfide prodrugs and in particular to lipid disulfide phosphodiester nucleosides and derivatives thereof, pharmaceutical compositions, and uses related thereto. According to one embodiment of the disclosure there is provided a compound of Formula I, or pharmaceutically acceptable salts or derivatives thereof, wherein substitutents are disclosed herein.
US11801254B2
Provided are novel formulations of 2-{[3,5-bis(trifluoromethyl)phenyl]carbamoyl}-4-chlorophenyl dihydrogen phosphate as described below and uses thereof.
US11801253B2
A method of treating and preventing secondary hyperparathyroidism in CKD by increasing or maintaining blood concentrations of both 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D in a patient by administering 25-hydroxyvitamin D3 with or without 25-hydroxyvitamin D2 and, as necessary, 1,25-dihydroxyvitamin D2 as a Vitamin D hormone replacement therapy.
US11801243B2
Methods for treating certain androgen receptor-positive forms of cancer using inhibitors of the CREB binding protein bromodomain are disclosed. In some methods, the AR-positive forms of cancer may be breast cancer, including triple negative forms, hormone receptor positive forms, and HER2-positive forms. In other methods, the AR-positive forms of cancer may be prostate cancer, including metastatic castration resistant prostate cancer. In some embodiments, methods of treating prostate cancer comprise the step of administering to a patient in need thereof the compound (1R,3R)-3-[(7S)-2-[(R)-(5-fluoro-2-methoxyphenyl)(hydroxy)methyl]-6-(methoxycarbonyl)-7-methyl-3H,6H,7H,8H,9H-imidazo[4,5-f]quinolin-3-yl]cyclohexane-1-carboxylic acid, or a pharmaceutically acceptable salt thereof.
US11801238B2
Described herein, in part, are methods of treating viral infections, such as coronavirus infections, in patients in need thereof, comprising administering to the patients a VPS34 inhibitor.
US11801237B2
Provided herein is an amorphous compound represented by Formula (I): and compositions thereof, which are useful in the treatment of disorders related to the activity of the c-KIT and PDGFRα kinases, and oncogenic forms thereof.
US11801231B2
Compositions that include from 0.1 wt-% to 8 wt-% of one or more compounds of formula (I) based on the total weight of the composition HOCH2—(CHOH)n—CH2NR1R2 (I) wherein R1 and R2 are independently selected from the group consisting of a hydrogen atom, an alkyl group, C(O)R3, and SO2R4; with R3 and R4 being independently selected from the group consisting of an alkyl group, an aryl group, and an aralkyl group; wherein n is an integer from about 2 to about 5; from 5 wt-% to 95 wt-% of one or more plant based oils based on the total weight of the composition; from 5 wt-% to 80 wt-% water based on the total weight of the composition and from 0.01 wt-% to 1 wt-% of one or more nonionic aromatic phenolic preservatives based on the total weight of the composition wherein the composition has a pH from 4.5 to 9.5, the composition is an emulsion, and the composition is edible.
US11801226B2
The invention relates to a pharmaceutical formulation, e.g. a paediatric formulation, of odevixibat, which comprises a plurality of small particles. The formulation may be used in the treatment of liver diseases such as bile acid-dependent liver diseases, and particularly cholestatic liver diseases such as biliary atresia, progressive familial intrahepatic cholestasis (PFIC), Alagille syndrome (ALGS) and paediatric cholestatic pruritus. The invention also relates to a process for the preparation of the pharmaceutical formulation.
US11801225B2
This invention provides novel oral dosage forms comprising a hops extract. The oral dosage forms are capable of activating bitter taste receptors expressed in the gastrointestinal tract. The applications include but are not limited to the use of the oral dosage forms for reducing energy intake and/or appetite in a subject.
US11801224B2
Compositions and methods for combination therapy are provided. The compositions comprise a multiple unit dosage form having both a therapeutic agent and a nutritional supplement. The combination therapy is useful for restoring a nutrient depletion associated with a particular disease state. Additionally, the combination therapy can prevent or attenuate the depletion of a nutrient caused, in whole or in part, by the co-administrated therapeutic drug. Methods of manufacturing the formulations are likewise described.
US11801223B2
The invention provides for thermostable lyophilized formulations, including vaccines and pharmaceutical compositions for inducing or enhancing an immune response, and methods of use thereof. The lyophilized formulations generally comprise an antigen and/or an adjuvant, a metabolizable oil, and a cake-forming excipient.
US11801217B2
The present invention provides a biodegradable drug delivery composition comprising: (i) a mixture of at least three different block copolymers, wherein each block copolymer is: (a) a biodegradable triblock copolymer having the formula: Av-Bw-Ax wherein A is a polyester and B is polyethylene glycol and v and x are the number of repeat units from 1 to 3,000 and w is the number of repeat units from 3 to 300 and v=x or v≠x; or (b) a biodegradable diblock copolymer having the formula: Cy-Az wherein A is a polyester and C is an end-capped polyethylene glycol and y and z are the number of repeat units with y=2 to 250 and z=1 to 3,000; and wherein the mixture comprises at least one (a) and at least one (b); and the weight ratio between (a) and (b) is 1:19 to 5:1; and (ii) at least one pharmaceutically active ingredient.
US11801205B2
[Problem] Providing a whitened capsule and a whitened film without using any white pigment such as titanium dioxide. [Solution] Provided is a film, a capsule, and a film forming composition, characterized by comprising: a film-forming polymer; and a whitening agent including either a surfactant or both a surfactant and a salt, and characterized in that the surfactant is selected from a fatty acid ester of polyhydric alcohol, a polyethylene glycol, a polypropylene glycol, a polyalkylene oxide derivative, an alkyl sulfate ester salt, and a saponin.
US11801195B2
A negative pressure massage apparatus includes a vacuum pump, two solenoid valves and a control board. The vacuum pump is used to generate a negative pressure outside the negative pressure massage apparatus. Two solenoid valves are used to control a gas flow input into the negative pressure massage apparatus. The control board is used to activate or stop at least one of the vacuum pumps, and the two solenoid valves. The present disclosure further includes a method of using the negative pressure massage apparatus.
US11801194B2
There is provided an information processing apparatus including a processing unit to set, on a basis of acquired input information, a feedback target range in which an object existing on inside serves as a target to be fed back to a user, in which the processing unit outputs information regarding the set feedback target range to an output unit.
US11801184B2
A head rest accessory is provided for coupling to a bed frame of a hospital bed. The head rest accessory includes a frame and a head rest mount coupled to the frame. A head rest is coupled to the head rest mount and includes a face rest shell. A first angle sensor measures a first tilt angle of the face rest shell. A second angle sensor measures a second tilt angle of the face rest shell.
US11801166B2
A dressing apparatus and methods for facilitating healing, the apparatus and methods involving a dressing member, an electromagnetically conductive element mechanically coupled with the dressing member, and a primary RFID device configured to transmit at least one output signal to the electromagnetically conductive element, to receive at least one return signal from the electromagnetically conductive element, and to provide an alert if the at least one return signal has a strength corresponding to at least approximately a threshold amount of fluid present in the dressing member, whereby healing is facilitated.
US11801162B2
An apparatus for treating dry eye, comprising composition chambers respectively containing a first composition and a second composition, wherein the first composition includes 95%-100% of aqueous substances and the second composition includes 95-100% volume of non-aqueous substances; and an air pump that is fluidically connected to the composition chambers and sequentially generates and propels the mists of the first composition and the second composition to a surface that corresponds to a cornea of an eye. The first mist, including droplets of the one or more aqueous substances forms a first film layer that corresponds to an aqueous layer of an artificial tear film, the second mist has a volume within a range of 0.1-3 microliters, and includes droplets of the one or more non-aqueous substances forms a second film layer that corresponds to a lipid layer of the artificial tear film with a thickness within a range of 10 nm-200 nm.
US11801159B2
Applicator (3) for cold treatment, comprising an applicator housing (5) with an inlet opening (18) and a leak tight tip (23). The applicator housing (5) encloses a channel body (20) extending between the inlet opening (18) and the leak tight tip (23). The applicator (3) is mounted or mountable in a releasable manner onto a pressurized dispenser (2) comprising a nozzle (7), such that the inlet opening (18) is in fluid communication with the nozzle (7). The applicator housing (5) is moveable between a rest position and a pressed position to activate the nozzle (7). The applicator housing (5) has release openings (26) which are closed in the pressed position.
US11801158B2
The present disclosure provides a coupling assembly (12) for an ostomy appliance (10) comprising a clamp arrangement (60), a first coupling and a second coupling. The clamp arrangement (60) comprises a clamp ring (61) mounted to the first and/or second coupling and a clamp locked mounted to the clamp ring (61). The clamp ring (61) comprises an inner circumference (62) adjustable between clamped and unclamped configurations. In the clamped configuration the clamp ring (61) is for maintaining the first and second couplings (20, 40) in a coupled configuration. The clamp lock (80) is adjustable into a locked configuration to lock the clamp ring (61) in the clamped configuration. The clamp lock (80) comprises a clamp actuator (81) moveable radially relative to the inner circumference (62) to unlock the clamp lock (80) from the locked configuration.
US11801147B2
A monoblock implant for fusing a cervical motion segment includes (a) an interbody portion configured to be positioned between superior and inferior vertebral bodies, of the cervical motion segment, with a first side of the interbody portion facing a first uncinate joint of the cervical motion segment and a second side of the interbody portion facing a second uncinate joint of the cervical motion segment, (b) a first wing extending away from the first side to extend into the first uncinate joint, and (c) a second wing extending away from the second side to extend into the second uncinate joint.
US11801146B2
An artificial intervertebral disc is configured to be inserted between adjacent human vertebrae. The artificial intervertebral disc includes a first connection block, a joint block and a second connection block. The joint block has a convex surface and a rear surface. The rear surface of the joint block is stacked on the first connection block. The second connection block is slidably stacked on the convex surface of the joint block, such that the second connection block is movable relative to the first connection block. In addition, the convex surface is a curved surface, and the convex surface is arranged off-axis with respect to the rear surface.
US11801145B2
The disclosed embodiments relate to a temporomandibular joint prosthesis including a joint portion, a fixation portion, and at least one flexible unit. The joint portion is configured to be as a temporomandibular joint and movably connected to cranial skeleton. The fixation portion is configured to be fixed on mandible. The flexible unit is located between and connected to the joint portion and the fixation portion. The fixation portion is movable with respect to the joint portion via the flexible unit.
US11801144B2
Methods of making medical devices are described. An example device is an implant used in spaces between vertebrae in a vertebral column of an animal. The example medical device includes a main body that has a lengthwise axis, a proximal end, a distal end, a length that extends from the proximal end to the distal end, an upper wall, a lower wall, a first lateral wall, a second lateral wall, and defines a plurality of pockets, a plurality of pocket supports, an interior chamber, a plurality of windows, and a recess. A pocket support of the plurality of pocket supports is disposed within each pocket of the plurality of pockets. A first mask includes an elongate member and a plurality of projections and is integrally formed with the medical device main body. The mask is used for performing a finishing process on the device and subsequently removed using a tool.
US11801141B2
A medical product, preferably for use in the treatment, more particularly in the filling up and/or closure, of a bone cavity, the product having structural elements connected to one another, the structural elements being dividable at least into two groups of structural elements, namely at least into a first group of structural elements and into a second group of structural elements, the structural elements of the first group having a lower hardness than the structural elements of the second group. Furthermore, a method for producing the medical product and a medical kit.
US11801137B2
Methods of deploying and securing a heart valve prosthesis are disclosed. A heart valve prosthesis having a plurality of anchor guides is loaded within a catheter-based delivery device, wherein each of the anchor guides is releasably engaged by a respective elongate member and wherein tensioning of the elongate members aids in collapsing the prosthesis during loading. The delivery device is advanced via a transcatheter procedure to position the heart valve prosthesis at an implantation site. The heart valve prosthesis undergoes controlled deployment by controlling the release of tension on the elongate members. After deployment of the heart valve prosthesis, an anchor tool is advanced along at least one elongate guide member to the anchor guide associated therewith and positioned at a securement site. When the securement site is reached, an anchor clip is released from the anchor tool to secure the prosthesis to the heart.
US11801131B2
A heart valve prosthesis includes a frame and a prosthetic disposed within a lumen of the frame. The frame includes a plurality of struts and crowns and has a radially collapsed state and a radially expanded state. A stiffness of the plurality of struts is varied by varying the width of at least one strut of the plurality of struts such that when the frame is in the radially expanded state, the frame has a substantially elliptical shape.
US11801130B2
Systems, methods, and devices for inserting an intraocular lens (IOL) into an eye may be provided. In an exemplary aspect, the present disclosure is directed to a haptic optic management system. The haptic management system may include a housing that includes a bore and a cavity disposed in a first surface of the housing. The cavity may include a first end portion, a second end portion, and a central portion, wherein the cavity provides access to the bore through the first surface of the housing. The haptic management system may include arms coupled to the housing. The haptic management system may include edge rollers coupled to the housing.
US11801124B2
A plurality of occlusal blocks for a mandibular relocation may include a first occlusal block including a first engagement surface and a first side surface with a first undercut formed in the first side surface of the first occlusal block. A second occlusal block may include a second engagement surface to engage the first engagement surface and a second side surface with a second undercut formed in the second side surface of the second occlusal block.
US11801120B2
Systems and methods for trimming dental aligners include a cut line system for identifying a first point and a second point based on a line around tooth (LAT) for a tooth of a model representative of a dentition of a user, where the first point is disposed on a tooth-gingiva interface of the tooth. The cut line system defines a cut plane at a distance from the first point toward the second point, where the cut plane intersects a line between the first point and the second point, identifies a plurality of points on the LAT based on the cut plane, defines a cut line based on the plurality of points on the LAT and the first point, and controls a cutting system to cut the dental aligner along the cut line.
US11801118B2
A dental treatment apparatus includes a handpiece holding a cutting tool in its head, a drive portion driving the cutting tool held by the head, and a control portion controlling the drive portion in accordance with a drive sequence. The drive sequence includes at least one forward rotation drive for rotating the cutting tool in a cutting direction to cut a treatment portion and at least one reverse rotation drive for rotating the cutting tool in a non-cutting direction. Under the control of the drive portion in accordance with the drive sequence, a cumulative amount of rotation which is an accumulation of an amount of rotation in forward rotation drive and an amount of rotation in reverse rotation drive does not exceed a set value at any time point.
US11801116B2
A medical device can include an elongate manipulation member, and a thrombectomy device connected to the elongate manipulation member. The thrombectomy device can have a first configuration and a second configuration, the thrombectomy device being expandable from the first configuration to the second configuration. The thrombectomy device can include an arcuate marker-mounting projection attached to a portion of the thrombectomy device configured to contact a thrombus. A marker can be coupled to, and extending around, the arcuate marker-mounting projection with the marker and the arcuate marker-mounting projection contacting each other at three discrete locations. A method for engaging a thrombus can include advancing a thrombectomy device to a location radially adjacent to a thrombus in a blood vessel. The thrombectomy device can be positioned such that a marker, disposed at a proximal end of a working length of thrombectomy device, is proximal to or longitudinally aligned with a proximal end of the thrombus, and can be expanded into the thrombus.
US11801102B2
Robotic devices, systems, and methods for use in robotic surgery and other robotic applications, and/or medical instrument devices, systems, and methods includes both a reusable processor and a limited-use robotic tool or medical treatment probe. A memory the limited-use component includes machine readable code with data and/or programming instructions to be implemented by the processor. Programming of the processor can be updated by shipping of new data once downloaded by the processor from a component, subsequent components can take advantage of the updated processor without repeated downloading.
US11801100B2
A system includes a control device, a manipulator configured to support a tool having a tool frame; and at least one processor coupled to the control device and the manipulator. The at least one processor configured to perform a method. The method includes receiving one or more images captured by an image-capturing system, the image-capturing system having an image frame. The tool is visible in the one or more images. The method also includes determining an estimated frame transform based on the one or more images. The estimated frame transform is used in defining an unknown frame transform between the image frame and the tool frame. The method also includes determining, in response to an input received at the control device, an output movement for the tool based on the estimated frame transform. The method also includes causing movement of the tool based on the output movement.
US11801099B2
Example embodiments relate to surgical systems having an end-effector assembly, first arm assembly, elbow joint section, and second arm assembly. First arm assembly forms a first arm assembly axis. First end of elbow joint section is pivotable relative to its second end. Second arm assembly includes second arm assembly body and first elbow drive assembly. Second arm assembly body forms a second arm assembly axis. First elbow drive assembly includes a first integrated motor and first elbow drive portion. First elbow drive portion is controllable by the first integrated motor to pivotally move the first arm assembly relative to an elbow axis. First arm assembly includes a second elbow drive assembly having a second integrated motor and a second elbow drive portion. Second elbow drive portion is controllable by the second integrated motor to rotate first arm assembly relative to first arm assembly axis.
US11801093B1
A system and method for transmyocardial laser revascularization (TMLR) in patients in need thereof, such as patients suffering from coronary artery disease. The system includes a Laser unit, an Electrocardiogram (EKG) unit, Vectorcardiography (VCG) unit, an Echocardiography unit, a spectrum Infrared sensor unit, and a control unit. The control unit can receive investigational data from different units and use the same to optimize the laser parameters. The Control unit can further include an AI module that can further analyze patient-related data, such as age and medical condition to further optimize the laser parameters. The laser unit can operate based on the optimized parameters to prevent unnecessary damage to the heart and allow maintaining the patency of the channels made by the laser for a longer duration.
US11801092B2
Apparatuses and methods for treating a heart failure patient by ablating a nerve of the thoracic splanchnic sympathetic nervous system to increase venous capacitance and reduce pulmonary blood pressure. A method comprising: inserting a catheter into a vein adjacent the nerve, applying stimulation energy and observing hemodynamic effects, applying ablation energy and observing hemodynamic effects, applying simulation energy after the ablation and observing hemodynamic effects and monitoring for presence of the lung in the ablation zone. An alternative method comprising: inserting a catheter into a vein adjacent the nerve, detecting that lung tissue is a safe distance from an ablation zone, and delivering ablation energy to the target nerve when lung tissue is a safe distance from the ablation zone.
US11801091B2
A device positionable in a cavity of a bodily organ (e.g., a heart) may discriminate between fluid (e.g., blood) and non-fluid tissue (e.g., wall of heart) to provide information or a mapping indicative of a position and/or orientation of the device in the cavity. Discrimination may be based on flow, or some other characteristic, for example electrical permittivity or force. The device may selectively ablate portions of the non-fluid tissue based on the information or mapping. The device may detect characteristics (e.g., electrical potentials) indicative of whether ablation was successful. The device may include a plurality of transducers, intravascularly guided in an unexpanded configuration and positioned proximate the non-fluid tissue in an expanded configuration. Expansion mechanism may include helical member(s) or inflatable member(s).
US11801090B2
A medical device may include an expandable energy delivery array reciprocally movable between a first configuration and a second configuration. The expandable energy delivery array may include a first assembly having a first proximal end piece, a first distal end piece, and one or more first energy transfer elements extending between the first proximal and first distal end pieces, and a second assembly having a second proximal end piece, a second distal end piece, and one or more second energy transfer elements extending between the second proximal and second distal end pieces. The second proximal end piece may be proximal to the first proximal end piece and the second distal end piece may be distal to the first distal end piece.
US11801089B2
A lumen-apposing access system may include a catheter and a cauterization tip. The cauterization tip may include a biasing member and a cautery element. The cauterization tip may move relative to the catheter between a first position in which the cautery element is electrically inactive, and a second position in which the cautery element is electrically active. The biasing member biases the cautery element in the first position.
US11801080B2
A method for providing a tool system for removing prosthetic cement from a bone of a patient undergoing a joint prosthesis replacement operation includes scanning the patient in the area of the joint prosthesis to obtain a profile of a line of intersection of a prosthetic cement/bone interface at its intersection with a longitudinally pre-selected plane; providing a guide member shaped as a stem of the prosthesis in a prosthetic cavity located in said prosthetic cement; and providing a cutting tool for forming a running cut through the prosthetic cement along the line of intersection. A stem of the cutting tool includes two protrusions along the length thereof. A guide member includes two grooves which each engage one of said protrusions. Grooves are profiled so the outer end of the stem is forced to follow a path corresponding to the profile of the line of intersection of the cement/bone interface.
US11801078B2
Intramedullary nails, systems, and methods. The intramedullary nail may include a generally elongate body extending from a first, distal end to a second, proximal end. The distal end may include one or more openings configured to receive one or more bone anchors that extend transversely through the distal end intramedullary nail, and thereby configured to secure the distal end of the nail. The proximal end may also include one or more openings configured to receive one or more bone anchors that extend transversely through the proximal end of the intramedullary nail, and thereby configured to secure the proximal end of the nail. In some embodiments, the proximal opening may contain one or more relief cuts.
US11801074B1
A bone fastener includes a head including a first receiver defining an implant cavity and a distal portion defining a plurality of adjacent grooves. The head further includes a second receiver defining an implant cavity. A first resilient member is configured for disposal within the plurality of adjacent grooves and a second resilient member is configured for disposal within the plurality of adjacent grooves. A shaft is aligned with the first receiver and is configured to engage tissue. Systems, surgical instruments, spinal constructs, implants and methods are disclosed.
US11801069B1
A device for orienting a medical object in respect of an object under examination includes an orientation element, a guide element, an ancillary element, and a light guiding device. The orientation element is movably mounted about a center of rotation and is configured for the longitudinal guidance of the medical object along a guide axis. The ancillary element includes an identification marker configured to be arranged in the center of rotation. The light guiding device is configured to emit a predefined distribution of light for specification of a path. The arrangement of orientation element and ancillary element may be moved about the center of rotation arranged on the path, such that the predefined distribution of light illuminates the identification marker with a predefined light pattern, when the guide axis of the orientation element is oriented in a defined positional relationship in respect of the path.
US11801060B2
Tools, devices and systems that include a generally cylindrical, hollow shaft, and a suction canister are provided with advantageous interconnectivity features and functions that enable ease of manufacturing, lowered manufacturing costs, and allow for a platform of different shaft embodiments and canister embodiments that may be manufactured in different combinations to form an array of unique instruments. The interconnectivity may be irreversible or reversible, and the connection features maintain an air tight seal between the components. Tools, devices and systems are also provided that include collection functionality that can be employed to manipulate the volume of tissue collected while using a tissue collection feature/function. This may be undertaken to restrict total volume of the collection chamber in a way that allows for continuous suction flow rate to take place while collecting the desired amount of tissue. Containing the tissue to a pre-set volume can enable a user to effectively ascertain the volume of tissue collected.
US11801059B2
A system for driving an ultrasonic device for bone cement removal and/or osteotomy operations comprises a control unit, a memory unit, and a connector for connecting together the control unit and a handset of the ultrasonic device. The control unit is configured to send a signal to the handset, receive from the handset a response to the signal sent, and check an operating condition of the ultrasonic device based on this response. Related device, method and computer program are also disclosed.
US11801058B2
The present specification discloses improved liquid embolic compositions, methods of making such liquid embolic compositions, and methods and uses for such liquid embolic compositions.
US11801047B2
A surgical cutting and fastening instrument. The instrument comprises a handle and an end effector connected to the handle. The end effector comprises upper and lower opposing jaw members, wherein the upper jaw member comprises a plurality of co-linear, separately actuatable, RF electrodes.
US11801046B2
A surgical instrument comprising a surgical end effector that comprises a first jaw and a second jaw that is movably supported relative to the first jaw for selective movement between an open position and closed positions. The surgical instrument further comprises a closure member that is axially movable in response to closing and opening motions. The closure member comprises at least one opening cam that protrudes therefrom to movably engage a corresponding cam surface on the second jaw such that upon application of the opening motion, the at least one opening cam movably engages the corresponding cam surface to move the second jaw to an open position, even when the jaws are under a load.
US11801042B2
A method of performing an operation, e.g. a spinal operation, on a patient using a retractor comprising a pair of blade assemblies which are adapted to open about a set of axes that are not parallel to a third spatial axis, and further comprising a pair of arms, which are adapted to move the pair of blade assemblies apart from one another in the third spatial axis. In the method, the blade assemblies are closed to assume a low profile, inserted into a relatively small incision, and stretched apart from each other, thereby stretching the skin about the incision to form an aperture longer than the incision. The blade assemblies are then opened by rotating the blades about the set of axes, stretching the skin around the incision in a second direction that is substantially perpendicular to the first direction (i.e. the direction of the incision.)
US11801038B2
An ultrasound imaging system (102) includes a touch screen user interface (122) and a touch screen controller (148). The touch screen user interface includes a touch panel (124). The touch panel includes a plurality of different clusters (510-522) of controls including a first cluster (512) in first sub-region and with a tactile control and one or more other cluster (510 and 514-522) in one or more other different sub-regions and with soft controls. The touch screen controller visually renders the one or more other clusters in the one or more different sub-regions spatially arranged with respect to each other based on a predetermined control cluster configuration for the touch screen user interface. The one or more other clusters include controls that correspond to different groupings of ultrasound imaging operations of the ultrasound imaging system.
US11801037B2
An ultrasound system 1 includes an ultrasound probe 2 and an image display device 3. The ultrasound probe 2 includes a transducer array 11 including a plurality of transducers, a transmitting and receiving unit 14 that transmits and receives ultrasonic waves using an aperture transducer group consisting of some transducers to generate a sound ray signal, and an image information data generation unit 19 that generates image information data from the sound ray signal. The image display device 3 includes a display unit 34. One of the ultrasound probe 2 and the image display device 3 includes a display image region determination unit 22 that determines a display image region obtained by excluding a shallow image region from an ultrasound image on the basis of the width of all of the transducers, the width of the aperture transducer group, and a steering angle range of a scanning line. The display unit 34 displays the ultrasound image based on the image information data only in the display image region.
US11801026B2
A radiographic imaging apparatus includes an image processor configured to perform image processing on a radiation image generated by an image generator, and a display configured to display a processed image that has been subjected to the image processing in the image processor. The image processor is configured to perform control to create the processed image showing an expanded portion in which a balloon introduced into a subject is expanded.
US11801013B2
A system and method of deploying a portable breath alcohol monitoring device. The method comprises inferring a rate of motion associated with the portable breath alcohol monitoring device; initiating, at a display screen of the portable breath alcohol monitoring device when the rate of motion is above a predetermined threshold, a request for a breath sample; determining, responsive to the request for the breath sample at the portable breath alcohol monitoring device, a violation; and reporting the violation to a remote server communicatively coupled to the portable breath alcohol monitoring device.
US11801010B2
A femoral region supporter (2) supports a femoral region of a user (1) in a travel direction. A force detector (3) detects force received by the femoral region supporter (2) from the femoral region of the user (1). A walking motion estimator (4) estimates walking motion of the user (1) based on the force detected by the force detector (3). The video generator (5) generates a video to be presented to the user (1) based on the walking motion estimated by the walking motion estimator (4). The video presenter (6) presents the video generated by the video generator (5) to the user (1).
US11800991B2
A method of guiding an interventional instrument within a patient anatomy comprises processing a target location within the patient anatomy and receiving a position for a tip portion of an interventional instrument at a first location within the patient anatomy. The method also comprises determining a three-dimensional distance between the first location and the target location and displaying a symbol representing the target location and a symbol representing the tip portion of the interventional instrument.
US11800988B1
In one embodiment, a system for monitoring heart rate variability including an electrode configured to be placed against a user’s chest and generate heart beat data and a data collection and processing device that receives the heart beat data from the electrode, the data collection and processing device being configured to execute a heart rate variability program configured to continually determine the user’s heart rate variability in real time based upon the heart beat data and to determine whether or not the user is in physiological distress based upon the determined heart rate variability.
US11800985B2
The present invention provides an electrocardiographic monitoring device comprising a device body configured to be attached to a user's chest; a plurality of electrodes provided on the device body; and a controller provided on the device body and connected to the electrodes in order to obtain the user's electrocardiographic signal waveforms. The electrocardiographic monitoring device of the invention can be applied in a blood pressure monitoring system for monitoring a user's blood pressure.
US11800984B2
There is provided a system for measuring a physiological parameter of a person indicative of physiological pathology, comprising: a plurality of remote non-contact sensors, each of a different type of sensing modality, at least one hardware processor executing a code for: simultaneously receiving over a time interval, from each of the plurality of remote non-contact sensors monitoring a person, a respective dataset, extracting, from each respective dataset, a respective sub-physiological parameter of a plurality of sub-physiological parameters, analyzing a combination of the plurality of sub-physiological parameters, and computing a physiological parameter indicative of physiological pathology according to the analysis, wherein an accuracy of the physiological parameter computed from the combination is higher than an accuracy of the physiological parameter independently computed using any one of the plurality of sub-physiological parameters.
US11800983B2
Featured are methods, apparatus and devices for detecting a hematoma in tissue of a patient. In one aspect, such a method includes emitting near infrared light continuously into the tissue from a non-stationary near infrared light emitter and continuously monitoring the tissue using a non-stationary probe so as to continuously detect reflected light. The near infrared light is emitted at two distances from a brain of the patient, so the emitted light penetrates to two different depths. Such a method also includes applying a ratiometric analysis to the reflected light to distinguish a border between normal tissue and tissue exhibiting blood accumulation.
US11800972B2
A supercontinuum light source can include a seed laser arranged to provide seed pulses with a pulse frequency Fseed; a pulse frequency multiplier (PFM) arranged to multiply the seed pulses by converting pulses having the pulse frequency Fseed to pump pulses with a pulse frequency Fpump, where Fpump is larger than Fseed; and a non-linear element arranged to receive said pump pulses and convert said pump pulses to pulses of supercontinuum light. The PFM can further include a splitter for splitting pulses into first and second sub beams each having the same pulse frequency, where the PFM is configured such that the sub beams experience different delays; and a combiner for combining said first and second sub beams into a beam having the pulse frequency that is greater than said same pulse frequency. The splitter can have an uneven splitter ratio.
US11800966B2
A medical system and an operating method of a medical system are disclosed. The medical system can operate an endoscope to perform an operation task with respect to a site of interest of an organ of concern in response to input from an operator. The medical system includes a controller that can record a model of the organ of concern generated during preoperative planning, and record the names of a plurality of sites in the organ of concern, and corresponding regions or points in the model with respect to a first coordinate system. The controller receives the name of the site of interest, and the operation task; associates the first coordinate system of the model with a second coordinate system of a display space displayed by a display image; and operates the endoscope with respect to the site of interest on the basis of the operation task.
US11800962B2
A mop base that is particularly practical in its use, above all when releasing a cloth retained along its transverse edges.
US11800958B2
The present disclosure provides a toilet seat hinge configured to couple a toilet seat to a toilet bowl. The toilet seat hinge including a base configured to be coupled to an upper surface of the toilet bowl, a post defining a pivot axis about which the toilet seat can rotate, the post being slidable onto the base in a direction parallel to the upper surface of the toilet bowl to couple the post to the base, and a cap pivotally coupled to the post. The cap being pivotable about the pivot axis to secure the post on the base.
US11800952B2
A steam valve for a cooking utensil and the cooking utensil are provided. The steam valve includes a valve base, a bonnet and a barrier member. The bonnet and the valve base form a mounting chamber. The valve base has a steam inlet, and at least one of the valve base and the bonnet has a steam outlet. The barrier member is mounted in the mounting chamber, the barrier member and a top wall of the bonnet define a first passage therebetween, steam flows from the steam inlet via the first passage to the steam outlet, and a bottom wall of the valve base corresponding to the barrier member is disposed obliquely such that liquid flows back to the steam inlet.
US11800948B2
A household appliance (10) is disclosed which comprises a liquid tank (12), wherein the tank is adapted for translational movement between a use position in which the tank is positioned within a housing (15) of the household appliance and a servicing position in which the tank is at least partially extracted from the housing, the household appliance further comprises biasing means (30) for biasing the tank towards the servicing position, and releasable latch means (36; 38; 58) for selectively arresting the tank in the use position or releasing the tank for movement towards the servicing position. In accordance with the invention: the household appliance (10) further comprises a carriage (24) associated to the tank (12) and configured for translational movement along guide means (28) provided in the housing (15); the biasing means (30) comprises a spring element configured to be loaded when the tank (12) is moved from the servicing position towards the use position; and the latch means comprises:20—a catch (36) provided at the carriage, —a locking member (38; 58) located at the housing (15) which in the use position of the tank (12) engages the catch (36) to arrest the tank in the use position, and —release means (40; 62) for disengaging the locking member25 from the catch (36).
US11800946B2
A cooking apparatus may include a housing having an open top surface and having a cooking space formed therein; a door provided on a top of the housing to open and close the cooking space; a container inserted into the housing, the container having an open top surface to receive food to be cooked therein; and a heating unit provided in the housing and contacting a bottom surface of the container to heat the container. The heating unit may include a heating unit body defining a support surface that supports the container; a heater provided in the heating unit body; and a rib that extends downward from the heating unit body to prevent water or foreign material from entering between the heating unit and a bottom of the housing.
US11800938B2
A child seat includes a seat portion fixedly connected with a first coupling part, a backrest frame fixedly connected with a second coupling part, the second coupling part being pivotally connected with the first coupling part so that the backrest frame is rotatable relative to the seat portion, a rotary element pivotally connected with the first coupling part, the rotary element being rotatable relative to the seat portion and the backrest frame, and a locking mechanism operatively connected with the backrest frame and operable to rotationally lock and unlock the rotary element with respect to the seat portion. The locking mechanism is configured to switch between a locking state and an unlocking state in response to a rotation of the backrest frame relative to the seat portion and the rotary element.
US11800937B2
A resilient unit comprises a number of wire coil springs 12, each of which is located within its own discrete pocket 14 formed by first, upper and second, lower layers 14a and 14b of material, preferably of non-woven material. The two layers 14a and 14b have been thermally, or ultrasonically, welded together at points 16 between the adjacent springs to create the pockets. The upper layer of material 14a differs from the lower layer of material 14b in respect of at least one characteristic.
US11800924B2
An oral care implement having a head and a handle. A plurality of tooth cleaning elements extend from an exposed front surface of the head. The handle has an open thumb gripping passageway extending between an exposed first surface of the handle and an exposed second surface of the handle opposite the exposed first surface. The handle also has a plurality of slots defining open slot passageways from the exposed first surface of the handle to the exposed second surface of the handle. The open thumb gripping passageway may be defined by a ring component that is fitted into an aperture in a body component. The open thumb gripping passageway may be a void space in the handle. The open slot passageways may be elongated along the handle and may serve to reduce a total amount of virgin material needed to manufacture the oral care implement.
US11800923B1
A recliner system, including a suspension point adapted to be mounted onto an upright anchor and to extend outwardly therefrom. The recliner system further includes a support platform and a plurality of cords, each attached to the support platform at two attachment points and suspended from the suspension point. The support platform is adjustable between an upright position and a reclined position by pulling on at least a subset of the plurality of cords.
US11800922B2
The present disclosure relates to a wearable pack. A wearable pack according to the present disclosure includes a first sheet formed in an elliptical shape, and a second sheet coupled to the first sheet, the second sheet being formed in a shape corresponding to the first sheet and including an opening that is sealable. An inner space is formed between the first sheet and the second sheet to accommodate a pack agent therein.
US11800921B2
A lipstick container for hot filling with replaceable lipstick assembly includes a base, a fixed tube, a lipstick assembly and a cap. The lipstick assembly includes a support tube, a sleeving tube, and an ascending and descending tube; the fixed tube includes a first axial channel; the support tube includes a second axial channel; the sleeving tube includes a third axial channel; the ascending and descending tube includes a forth axial channel and a spiral groove portion screwed with internal threads of the support tube. The fixed tube is put on the sleeving tube and the ascending and descending tube is disposed through the sleeving tube and the support tube; an end of the sleeving tube urging against the support tube.
US11800913B2
A hand-push umbrella has a column, an upper nest at the top of the column, a lower nest on the column, a plurality of long rods having an upper end mounted on the upper nest and a plurality of first short rods having a lower end mounted on the lower nest and an upper end hinged to the middle portion of the long rod; a first retainer ring sleeved on the column above the lower nest and fixed with the column, a handle is connected to the bottom of the lower nest, and a handle control mechanism is disposed inside the lower nest. The umbrella is simple and can be easily unfolded and folded. A tray and a plurality of second short stretchers greatly strengthen the support to the canopy and improve the stability of the structure.
US11800907B2
The present specification discloses headwear configured to permit the user to easily don an item of eyewear, such as prescription glasses, reading glasses, sun glasses, safety glasses, and the like. The present headwear provides a unique pocket design on each side with an eyewear temple aperture located within the pockets. The pockets are created by forming a z-folded configuration out of a fabric panel for each pocket and tacking the three layers of material together, above and below the eyewear temple aperture. Each of the pockets are positioned forward of at least part of the ears, and open towards the user's anterior. The outermost panel of each of the pockets protrudes from the sides of the headwear to provide sufficient clearance for the temples of the eyewear to easily slip into the pockets and through the eyewear temple apertures.
US11800904B2
An attachment system is provided for attaching a neck protector to a face mask. The attachment system includes a cord and a connector where the connector comprises a first portion and a second portion with corresponding engaging elements and a throughbore defined through each of the first portion and the second portion for receiving the cord. Kits for attaching a neck protector to a face mask are also provided where the kits include one or both of the neck protector and face mask together with the attachment system.
US11800903B2
Provided is an air injection device. The air injection device includes: a body having an air passage formed therein; and an opening and closing part coupled to one end periphery of the body and having an opening and closing protrusion protruding from an inner surface thereof toward the air passage of the body by a given length in such a manner as to open and close the air passage, wherein the opening and closing protrusion is moved in a first direction toward the body or in a second direction opposite to the first direction by means of a user's control for the opening and closing part, and the movement of the opening and closing protrusion in the first direction or in the second direction is guided by means of a guide groove formed on an outer peripheral surface of one end portion of the body and a guide protrusion formed on the inner peripheral surface of the opening and closing part in such a manner as to be inserted into the guide groove.
US11800892B2
A system for smoking a product includes a vase for containing a liquid. The vase has a closed bottom, and a side wall extending from the closed bottom and an open top that is unobstructed. The system further includes a bottle for inserting into and removing from the vase. The bottle has an open bottom, an open top, a flange circumscribing the bottle adjacent the open top, and a conical opening in the open top that is unobstructed. In addition, the system includes a grommet mounted to the open bottom of the bottle such that the open bottom is substantially unobstructed. Lastly, the system includes a bowl with a conical exterior that is complementary in shape to the conical opening in the bottle. The bowl can form a conical, glass-to-glass seal with the bottle.
US11800891B2
An aerosol-generating article is provided, including: an aerosol-forming substrate configured to be heated to generate an aerosol, the aerosol-generating article not including an aerosol-forming substrate that is configured to be combusted to produce smoke; and an outermost wrapper around at least a portion of the aerosol-forming substrate, an outer surface of the outermost wrapper forming at least part of an outer surface of the aerosol-generating article, the outermost wrapper including a metallized substrate including a substrate layer and a metal layer radially outward of the substrate layer, and the substrate layer being coated with the metal layer by vapour deposition.
US11800885B2
The present invention relates to a meat processed food, into which a gel-like material is locally and quantitatively filled. Provided is a method for producing a meat processed food, having a step of cooling a gelling agent solution prepared by adding a gelling agent into water and then heating and dissolving the gelling agent, so as to prepare a gel-like material having fluidity; and a step of filling the gel-like material into a plurality of predetermined positions inside a meat-containing raw material.
US11800880B2
Disclosed is a method for cutting chewing gum, the method including providing a chewing gum sheet to at least one cutting device; applying oil to said at least one cutting device; and cutting said chewing gum sheet via said at least one cutting device. Further disclosed is a method for cutting chewing gum, the method including providing a chewing gum sheet to at least one cutting device; cutting said chewing gum sheet via said at least one cutting device; and separating chewing gum from said at least one cutting device via a directing of compressed air onto said at least one cutting device.
US11800879B2
The present disclosure provides frozen confectionary products comprising a base frozen confection, wherein the base frozen confection comprises i) a vegetable or vegetable derivative component and ii) one or more sweetening agents. The frozen confectionary products provided in the present disclosure may optionally comprise an oil, an emulsifier, a stabilizer, a salt, and water.
US11800876B2
A producing method for a dough for food in which a filling is wrapped with a dough sheet. The producing method includes the steps of: a) thinly extending and baking a dough liquid so as to prepare a thin baked dough; b) winding the thin baked dough around a mold member narrowed toward a tip; c) freezing the thin baked dough wound around the mold member so as to prepare a three-dimensional dough hardened in a manner wound around the mold member; and d) detaching the mold member from the three-dimensional dough. The method can speedily provide food in which a filling is wrapped with a dough sheet such as a crepe.
US11800870B2
Methods and compositions for controlling undesired vegetation in animal grazelands.
US11800867B2
The invention relates to biting arthropod repellent compositions comprising nootkatone. The application also relates to a method of repelling said biting arthropods by application of the nootkatone composition to a hard or soft surface, to a method of treating an arthropod infestation and to a method of reducing the transmission of a parasite or disease pathogen spread by a biting arthropod using the nootkatone composition.
US11800866B2
A method of controlling aphid pests includes exposing the aphid pests on a host plant to an effective pest-controlling amount of a triketone compound having the following formula:
US11800864B2
The present invention provides a composition for inhibiting ice recrystallization, including: A nucleic acid structure comprising a scaffold nucleic acid folded at predetermined positions to form a plurality of strands, and a plurality of staple nucleic acids, wherein at least a portion thereof has a complementary sequence to at least a portion of the scaffold nucleic acid, thereby binding to the scaffold nucleic acid to form a double strand. Therefore, it is possible to increase a survival rate of cells due to having excellent effect of inhibiting ice recrystallization upon cryopreservation of the cells, and maintain a texture of food even when using the composition in the freezing of food.
US11800860B2
A multi-axis linkage for use with a collapsible boom of an agricultural vehicle is disclosed. The collapsible boom includes a first boom segment having a first truss and a second boom segment having a second truss. The multi-axis linkage includes a first linear motor, a second linear motor, and a multipoint winged link. The first linear motor has a piston rod. An end of the piston rod is coupled to the first truss. The second linear motor has a second piston rod. An end of the second piston rod is coupled to the second truss. The multipoint winged link connects to the first linear motor, the second linear motor, the first boom segment, and the second boom segment.
US11800859B2
The present invention relates to Charcot-Marie-Tooth disease 2A (CMT2A) harboring the p.Arg364Trp or p.His361Tyr Mfn2 mutation, whose human counterpart results in severe, early-onset axonal neuropathy for p.Arg364Trp Mfn2 mutation in fertilized rat eggs. Cohorts of mutants and wild type littermates were characterized with multiple motor deficits that worsened over time. Separate cohorts of mutant and wild type at 7, 40, and 48 weeks showed reduced density of myelinated axons and active axonal degeneration in distal but not proximal nerves, as well as axonal degeneration in the fasciculus gracilis of the cervical spinal cord at 40 and 48 weeks not present in 7-week-old cohort Mfn2 mutants, or wild type at 7 or 40 weeks. The p.His361Tyr Mfn2 mutation using CRISPR/Cas9 showed abnormalities in gait dynamics at 8 weeks and lengthening of gait cycle at 16 weeks. The invention provides progressive axonal neuropathy for examining pathogenesis and treatment of CMT2A.
US11800856B2
The present invention discloses a recirculating aquaculture system (RAS) and method for shrimp culture through SBR wastewater treatment. The RAS includes a control cabinet, culture tanks, a clean water tank, a clean water filling pipeline, a drainage pipeline, a buried activated sludge tank and a solid-liquid separation mechanism. The solid-liquid separation mechanism comprises a sludge pump, an input pipe, a plate and frame type filter press and a liquid output pipe. An input end of the sludge pump is immersed in sewage of the buried activated sludge tank; and a clean water output end of the plate and frame type filter press is connected with the buried activated sludge tank through the liquid output pipe.
US11800854B1
A system for transferring heat between a first livestock animal and a second livestock animal may include a first element positionable adjacent to the first livestock animal to transfer heat from a first fluid to a first thermally conductive surface on the first element, a second element positionable adjacent to the second livestock animal to transfer heat from a second fluid to a second thermally conductive surface on the second element, and a heat exchange assembly configured to transfer heat to the first fluid from the second fluid. The heat exchange assembly may include a first heat exchanger receiving the first fluid from the first element, a second heat exchanger receiving the second fluid from the second element, and a refrigeration apparatus utilizing a refrigerant to exchange heat between the first and second heat exchangers.
US11800848B2
The present disclosure provides alfalfa plants exhibiting broad spectrum resistance to Race 1, Race 2, and Race 5 anthracnose. Such plants may comprise novel introgressed genomic regions associated with disease resistance from Race 1, Race 2, and Race 5 anthracnose. In certain aspects, compositions, including novel polymorphic markers and methods for producing, breeding, identifying, and selecting plants or germplasm with a disease resistance phenotype are provided. Also provided are alfalfa varieties designated as C0416C4164 and H0415C4114. Provided by the invention are the seeds, plants and derivatives of alfalfa varieties C0416C4164 and H0415C4114. Also provided by the invention are tissue cultures of alfalfa varieties C0416C4164 and H0415C4114, and the plants regenerated therefrom. Still further provided by the invention are methods for producing alfalfa plants by crossing alfalfa variety C0416C4164 or H0415C4114 with itself or another alfalfa variety and plants produced by such methods.
US11800847B2
A soybean cultivar designated 05050112 is disclosed. The invention relates to the seeds of soybean cultivar 05050112, to the plants of soybean cultivar 05050112, to the plant parts of soybean cultivar 05050112, and to methods for producing progeny of soybean cultivar 05050112. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 05050112. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 05050112, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 05050112 with another soybean cultivar.
US11800845B1
A novel maize variety designated X95R051 and seed, plants and plant parts thereof are produced by crossing inbred maize varieties. Methods for producing a maize plant by crossing hybrid maize variety X95R051 with another maize plant are disclosed. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X95R051 through backcrossing or genetic transformation, and to the maize seed, plant and plant part produced thereby are described. Maize variety X95R051, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X95R051 are provided. Methods for producing maize varieties derived from maize variety X95R051 and methods of using maize variety X95R051 are disclosed.
US11800844B2
A novel canola variety designated S00635 and seed, plants and plant parts thereof. Methods for producing a canola plant that comprise crossing canola variety S00635 with another canola plant. Methods for producing a canola plant containing in its genetic material one or more traits introgressed into S00635 through backcross conversion and/or transformation, and to the canola seed, plant and plant part produced thereby. Hybrid canola seed, plant or plant part produced by crossing the canola variety S00635 or a locus conversion of S00635 with another canola variety.
US11800832B2
A hybrid flute for a stalk roll may be configured with a sharp edge positioned between a first blunt edge and a second blunt edge along a length of the flute edge. The flute edge may extend radially outward from a main cylinder of the stalk roll. The flute edge may be engaged with a radius at the base of the flute edge, and a flute base may extend from the radius. A plurality of flute bases positioned adjacent to one another may be configured to form a main cylinder for the stalk roll.
US11800829B2
A work machine includes a work machine actuator, a position sensor configured to sense a geographic position of the work machine on a worksite and a control system configured to receive an indication of a thematic map of the worksite that maps variable values to different geographic locations on the worksite, generate a set of clusters based on the variable values and a geospatial control zone constraint, identify, based on the set of clusters, a plurality of control zones that are correlated to the worksite and have associated setting values, and generate control signals to control the work machine actuator based on the geographic position of the work machine relative to the plurality of control zones and the setting values associated with the control zones.
