An integrated circuit is provided that contain n-channel and p-channel metal-oxide-semiconductor transistors having body terminals. Adjustable transistor body bias circuitry is provided on the integrated circuit that provides body bias voltages to the body terminals to minimize power consumption. The adjustable body bias circuitry can be controlled using programmable elements on the integrated circuit that are loaded with configuration data. The integrated circuit may be a programmable logic device integrated circuit containing programmable logic. The adjustable body bias circuitry can produce an adjustable negative body bias voltage for biasing n-channel metal-oxide-semiconductor transistors. The adjustable body bias circuitry contains a bandgap reference circuit, a charge pump circuit, and an adjustable voltage regulator.