The invention relates to the field of the development of new medicines, and relates to the field of the development of new medicines of anti-tumor medicines, in particular to a compound. A structure of the compound is shown as a general formula I, wherein A is selected from 4- nitro-substituted phenyl shown as a structural formula II, 4-alkoxy substituted phenyl shown as a structural formula III and a substituted heterocyclic ring shown as a structural formula IV or a structural formula V, and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17 and R18 are selected from hydrogen, halogen, hydroxyl, amido, substituted amio, cyan, alkyl, alkoxy, nitryl, acylamino, halogenated alkyl, acyl, formyl, carboxy, carbalkoxy or substituted alkyl having 1 to 3 carbon atoms independently, and R5, R6, R7 and R8 are not the hydrogen simultaneously; R9 is selected from alkyl having 1 to 3 carbon atoms or substituted alkyl having 1 to 3 carbon atoms; and X and Y are selected from nitrogen, oxygen or sulphur independently. The compound has the effects of resisting abnormal neovascularization and inhibiting the polymerization of microtubulin and has the advantages of high activity and low toxicity.