The invention discloses a method and a device for simulation of an intelligent vehicle, and belongs to the field of computer simulation. The method comprises the following steps of: acquiring a virtual model file, wherein the virtual model is used for generating a three-dimensional virtual scene, the three-dimensional virtual scene is used for simulating actual travelling scenes of the intelligent vehicle, the three-dimensional virtual scene is built by virtual models, the virtual models comprise a virtual intelligent vehicle model and an environment model, and the environment model comprises virtual lanes; generating the three-dimensional virtual scene according to the virtual model file; determining a travelling path of the virtual intelligent vehicle in the three-dimensional virtual scene; and playing a process where the virtual intelligent vehicle moves in the three-dimensional virtual scene according to the travelling path. The device comprises an acquisition module, a generation module, a determining module and a play module. The method and the device can simulate the intelligent vehicle in the three-dimensional virtual scene, and present the simulation result in a way of animation, thus, researchers can visually watch the dynamic simulation process.