The invention discloses a highway passenger car operation speed prediction method. Through consideration from a driver's vision angle, through adoption of a driver's visual road surface area as a research index of the passenger car operation speed prediction method, and through acquisition of the driver's visual road surface area and a passage car driving speed corresponding to the driver's visual road surface area, a mathematical prediction model is established, and a passenger car operation speed prediction equation is finally obtained. The method can effectively guarantee the continuity of a road in linearity, the continuity of a driver on vision and the continuity of a vehicle on a driving speed; and, through the method, flat, vertical and horizontal indexes of an initial road and irrationalities of combinations of the indexes can be verified accurately and efficiently.