The invention provides an engine oil-gas separation device. The engine oil-gas separation device comprises a device housing, a tapered top shell and an oil-gas flow guide cylinder body combination. The oil-gas flow guide cylinder body combination is fixedly mounted inside the device housing; the tapered top shell is mounted on the top of the device housing; the oil-gas flow guide cylinder body combination is composed of one oil-gas flow guide cylinder body unit or a plurality of oil-gas flow guide cylinder body units which are combined side by side. Each oil-gas flow guide cylinder body unit comprises a single cylinder body, a left-handed rotation blade and a right-handed rotation blade and further comprises a filter net assembly. The left-handed rotation blades and the right-handed rotation blades are fixed to the inner walls of the corresponding single cylinder bodies. The filter net assemblies are disposed on the tops of the corresponding single cylinder bodies. A vent hole is formed in the tapered top shell. Compared with the prior art, the engine oil-gas separation device has the following advantages that different numbers of the oil-gas flow guide cylinder body units can be organized and combined to form the engine oil-gas separation device according to the oil-gas separation requirements of an engine, so that the emission problem due to exhausting of oil fog particles and exhaust gas in an engine crank case out of the engine is solved, and the increasingly strict vehicle emission requirements are met.