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发明公开
CN107304223A 硼替佐米晶型及其制备方法和用途 无效 - 撤回

硼替佐米晶型及其制备方法和用途
摘要：
一种硼替佐米晶型，该晶型在X射线粉末衍射图谱中具有以下2θ测定的特征峰：5.7°±0.2°、7.5°±0.2°、9.8°±0.2°、11.3°±0.2°、12.9°±0.2°、15.0°±0.2°、15.3°±0.2°、17.0°±0.2°、18.1°±0.2°、20.3°±0.2°、20.5°±0.2°、21.4°±0.2°和22.0°±0.2°。本发明硼替佐米晶型具有较好的稳定性和较低的吸湿性。
摘要（英）：

The invention relates to a bortezomib crystal form. The bortezomib crystal form has the following characteristic peaks measured at 2 theta in an X-ray powder diffraction pattern: 5.7 degrees +/- 0.2 degrees, 7.5 degrees +/- 0.2 degrees, 9.8 degrees +/- 0.2 degrees, 11.3 degrees +/- 0.2 degrees, 12.9 degrees +/- 0.2 degrees, 15.0 degrees +/- 0.2 degrees, 15.3 degrees +/- 0.2 degrees, 17.0 degrees +/- 0.2 degrees, 18.1 degrees +/- 0.2 degrees, 20.3 degrees +/- 0.2 degrees, 20.5 degrees +/- 0.2 degrees, 21.4 degrees +/- 0.2 degrees and 22.0 degrees +/- 0.2 degrees. The bortezomib crystal form provided by the invention has higher stability and lower moisture absorption.

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