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发明公开
CN107759587A [1,2,4]三唑并[1,5-a]吡啶类化合物及其制备方法和医药用途 有权

[1,2,4]三唑并[1,5-a]吡啶类化合物及其制备方法和医药用途
摘要：
本发明涉及[1,2,4]三唑并[1,5-a]吡啶类化合物及其制备方法和医药用途。特别地，本发明涉及通式I所示的化合物、其制备方法及含有该化合物的药物组合物，及其作为JAK激酶抑制剂的用途，该化合物及其含有该化合物的药物组合物可以用于治疗与JAK激酶活性相关的疾病，例如炎症、自身免疫性病症、癌症等。其中通式I中的各取代基的定义与说明书中的定义相同。
摘要（英）：

The invention relates to a [1,2,4]triazol[1,5-a] pyridine compound as well as a preparation method and medical application thereof. Particularly, the invention relates to the compound shown in a general formula I, the preparation method of the compound, a medicinal composition containing the compound and application of the compound as a Janus kinase inhibitor. The compound and the medicinal composition containing the compound can be used for treating diseases related to the activity of Janus kinase, such as inflammation, autoimmune disease and cancer. The definitions of all substituent groupsin the general formula I are identical with those of the description. (The general formula is shown in the description).

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