The invention discloses a making method of selenium-rich sprouted brown rice cake, comprising the sequential steps of soaking, to be specific, soaking brown rice with hull in water in immersed manner,adding food-grade sodium selenite, and soaking for 6-8 h so that the brown rice with hull enters sprouting state to obtain sprouted brown rice; deactivating enzymes; hulling; grinding; making dough;forming; baking; cooling; packaging. Selenium in the made cake is present in the form of organic selenium like in natural food, the content of organic selenium is high, physiological activity and absorption rate of selenium can be increased, toxicity of selenium can be reduced, and absorption by the human body is benefited. The making method also has the advantages of short production cycle and low production cost.