The invention provides a copper-zirconium-base catalyst for preparing chlorine by oxidizing hydrogen chloride, and a preparation method and application thereof, belonging to the technical field of catalysis. The catalyst contains the following components in percentage by mass: 10-20% of active components (cupric oxide and zirconium dioxide), 70-80% of support aluminum oxide and the balance of aid.The mass ratio of the copper to the zirconium in the active components is 0.1-10. A co-impregnation method or consecutive impregnation method can be adopted for preparation. The catalyst has the characteristics of high activity and low copper loss rate at the reaction temperature of 300-400 DEG C at the raw material space velocity of 500-1000L/(kg-cat.h), and had favorable commercial applicationprospects.