Provided is a double-slider incremental launching construction method suitable for a high-pier large-span steel truss bridge. In the method, by utilizing the eccentric stress performance of overall joints of a steel truss girder, front and rear sliders and front, middle and rear vertical jacks are arranged between the same joints and under adjacent joints, incremental launching is carried out in one inter-joint distance step by step, different vertical supporting modes are adopted according to the incremental launching steps, and the bending moment of a slideway beam and the bending moment ofa pier body are reduced so that the stress of the pier body can meet design requirements; to prepare for the incremental launching state, the front slider is supported at the allowable eccentricity position of the joints of the steel truss girder, the rear slider is supported under the joints of the steel truss girder, at this time, supporting is provided between the adjacent joints, the single-support reaction is small, the bending moment of the slideway beam and the eccentric bending moment of the pier body are both small, forward incremental launching is carried out in the incremental launching direction, the front and rear sliders are switched through jacking and falling of the front, rear and middle vertical jacks, and in double-slider supporting, the single-support reaction is reduced; in single-slider supporting, the distance between the maximum point reaction position and the pier center is reduced, and thus the bending moment of the slideway beam and the bending moment of thepier body are reduced.