The invention relates to a method for inhibiting leaching of germanium in oxygen pressure leaching process of germanium-rich zinc concentrate, and belongs to the field of wet metallurgy of non-ferrousmetal. The method comprises the following technological steps of (1) performing one-stage oxygen pressure leaching on -320-mesh germanium-rich zinc concentrate, adding a two-stage oxygen pressure leaching solution, supplementing sulfuric acid, introducing industrial oxygen, controlling the total pressure, reaction temperature and leaching time, filtering, performing two-stage oxygen pressure leaching on one-stage filter cake, neutralizing one-stage filtrate to further remove iron and germanium, adding zinc powder to purify and remove impurities, and electrically depositing zinc; (2) performing the two-stage oxygen pressure leaching on one-stage oxygen pressure filter residues, controlling the amount of final acid to be 20 to 30g/L, introducing the industrial oxygen, controlling the totalpressure to 1.0 to 1.2MPa, reaction temperature to 140 to 150 DEG C and leaching time to 1.0h, filtering, recycling sulfur, lead, silver and germanium from two-stage leaching residues, and returning the two-stage leaching solution back to the one-stage oxygen pressure leaching. The method has the advantage that the leaching of germanium is inhibited in the oxygen pressure leaching process of the germanium-rich zinc concentrate, and the germanium is enriched into the leaching residues, so that the problems of long process, complicated technology, high consumption rate of neutralizer and the like in the subsequent treatment process of the germanium-rich zinc concentrate oxygen pressure leaching solution are solved.