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发明公开
CN108796023A 一种高纯度植物甾醇单体酯的制备方法 审中-实审

一种高纯度植物甾醇单体酯的制备方法
摘要：
本发明公开了及一种高纯度植物甾醇单体酯的制备方法，包括，制备植物甾醇单体酯粗品：植物甾醇单体和不饱和脂肪酸甲酯经脂肪酶催化发生转酯化反应，得到植物甾醇单体酯粗品，其中，所述的植物甾醇单体纯度为98％以上；植物甾醇单体酯的纯化：植物甾醇单体酯粗品经硅胶柱层析处理，得到所述高纯度植物甾醇单体酯。本发明合成工艺简便，反应条件温和，无任何有机溶剂的添加和消耗，降低了生产成本，对设备无特殊要求，适合大规模工业化生产。
摘要（英）：

The invention discloses a preparation method of high-purity phytosterol monomer ester. The preparation method comprises the following steps: preparing a phytosterol monomer ester crude product: catalyzing a phytosterol monomer and unsaturated fatty acid methyl ester, through lipase to be subjected to transesterification reaction, so as to obtain the phytosterol monomer ester crude product, whereinthe purity of the phytosterol monomer is 98 percent or more; purifying the phytosterol monomer ester: carrying out silica gel column chromatography treatment on the phytosterol monomer ester crude product to obtain the high-purity phytosterol monomer ester. The preparation method disclosed by the invention has the advantages of simple and convenient synthesis technology, mild reaction conditions,no addition and consumption of any organic solvent, reduction of production cost and no special requirements on equipment, and is suitable for large-scale industrialized production.

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