The invention discloses a multi-person plateau life pressurizing cabin and a control method thereof, and relates to the technical field of pressurization and oxygen supply devices. The main structureof the multi-person plateau life pressurizing cabin comprises an equipment cabin, a transition cabin and a living cabin. The pressure and the oxygen are provided for the transition cabin and the living cabin through pressurization equipment in the equipment cabin, so that the pressure and the oxygen partial pressure in the transition cabin and the living cabin can be obviously higher than the external atmospheric pressure. Meanwhile, the personnel entering and exiting process in the living cabin can only change the pressure in the transition cabin, so that the influence on the personnel in theliving cabin is avoided. A safety valve, a manual pressure releasing valve, pressurization and air treatment equipment and minimum safety protection equipment are respectively arranged in each of theliving cabin and the transition cabin. Therefore, the safety in the transition cabin and the living cabin can be guaranteed to the largest extent. The occurrence of accidents caused by too large pressure or too small ventilation quantity due to system faults can be avoided. According to the invention, by adopting the control method of the multi-person plateau life pressurizing cabin, users can select a cabin entering mode and a cabin exiting mode according to actual requirements, and the control method is simple and clear.