The invention discloses a chili pepper cleaning and degerming method. The chili pepper cleaning and degerming method comprises the following steps of performing cleaning preparation: remaining and taking chili pepper rhizomes of which the length is 2cm, and cutting off surplus rhizomes; and performing impurity removal: putting the chili peppers needing to be cleaned in an ultrasonic cleaning machine, performing ultrasonic cleaning, and then performing filtration with a 100-mesh filter screen. According to the chili pepper cleaning and degerming method disclosed by the invention, firstly, bacteria in water and on surfaces of the chili peppers can be killed and removed, and then the chili peppers are cleaned through clean water, so that various impurities can be better removed; secondly, ultrasonic waves are combined with SAEW, so that growth of microorganisms on the surfaces of the chili peppers can be restrained, the physiological metabolism of the chili peppers in the storage period can also be regulated, and the quality of the chili peppers in the storage period can be improved; and when the ultrasonic waves propagate in liquid, instantaneous high pressure generated through cavitation effects can promote chemical sterilization agents to infiltrate into cell membranes, and besides, the cavitation effects can also accelerate decomposition of microorganism cells, so that the degerming efficiency of the SAEW can be improved, and better usage prospects can be brought.