发明公开
- 专利标题： Aminonaphthacene derivatives and their production
- 专利标题（中）： Aminonaphtacen衍生物和它们的制备。
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申请号： EP83306384.5申请日： 1983-10-20
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公开(公告)号： EP0107486A1公开(公告)日： 1984-05-02
- 发明人: Ishizumi, Kikuo , Ohashi, Naohito , Tanno, Norihiko , Sato, Hiromi , Fukui, Masaru , Morisada, Shinya
- 申请人： SUMITOMO CHEMICAL COMPANY, LIMITED
- 申请人地址： Kitahama 4-chome 5-33 Chuo-ku Osaka 541 JP
- 专利权人： SUMITOMO CHEMICAL COMPANY, LIMITED
- 当前专利权人： SUMITOMO CHEMICAL COMPANY, LIMITED
- 当前专利权人地址： Kitahama 4-chome 5-33 Chuo-ku Osaka 541 JP
- 代理机构： Collier, Jeremy Austin Grey (GB)
- 优先权： JP186514/82 19821022
- 主分类号： C07H15/252
- IPC分类号： C07H15/252 ; C07H15/24 ; A61K31/70 ; C07C97/18 ; C07C103/42 ; C07D413/04
摘要：
9-Aminonaphthacene derivative having the formula:
wherein R 1 and R 2 are both hydrogen atoms or either one of them is a hydrogen atom and the other is hydroxy group or methoxy group; R 3 is acetyl group or 1-hydroxyethyl group; R 4 is a hydrogen atom or halogen-substituted lower alkanoyl group; R 5 is a hydrogen atom, hydroxy group, lower alkanoyloxy group, amino group, halogen-substituted lower alkanoylamino group or morpholino group; R 6 is a hydrogen atom, hydroxy group, lower alkanoyloxy group or tetrahdropyranyl- oxy group; R' is a hydrogen atom, methyl group, hydroxymethyl group or lower alkanoyloxymethyl group; R is a hydrogen atom, hydroxy group or lower alkanoyloxy group, and n is zero or one, which is useful as anti-cancer chemical agents with lower toxicity.
wherein R 1 and R 2 are both hydrogen atoms or either one of them is a hydrogen atom and the other is hydroxy group or methoxy group; R 3 is acetyl group or 1-hydroxyethyl group; R 4 is a hydrogen atom or halogen-substituted lower alkanoyl group; R 5 is a hydrogen atom, hydroxy group, lower alkanoyloxy group, amino group, halogen-substituted lower alkanoylamino group or morpholino group; R 6 is a hydrogen atom, hydroxy group, lower alkanoyloxy group or tetrahdropyranyl- oxy group; R' is a hydrogen atom, methyl group, hydroxymethyl group or lower alkanoyloxymethyl group; R is a hydrogen atom, hydroxy group or lower alkanoyloxy group, and n is zero or one, which is useful as anti-cancer chemical agents with lower toxicity.
公开/授权文献
- EP0107486B1 Aminonaphthacene derivatives and their production 公开/授权日：1987-04-29
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