发明公开
EP0128370A2 Diazotetracyclic compounds and process for preparing the same
失效
Diazotetracyclische化合物和它们的制备方法。
- 专利标题： Diazotetracyclic compounds and process for preparing the same
- 专利标题（中）： Diazotetracyclische化合物和它们的制备方法。
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申请号： EP84105338.2申请日： 1984-05-11
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公开(公告)号： EP0128370A2公开(公告)日： 1984-12-19
- 发明人: Hirata, Tadashi , Kobayashi, Shigeru , Takahashi, Keiichi , Morimoto, Makoto Kyowa Hakko Kogyo Seiwa Ryo , Arai, Yuko
- 申请人： KYOWA HAKKO KOGYO CO., LTD.
- 申请人地址： 6-1, Ohtemachi 1-chome Chiyoda-ku, Tokyo-to JP
- 专利权人： KYOWA HAKKO KOGYO CO., LTD.
- 当前专利权人： KYOWA HAKKO KOGYO CO., LTD.
- 当前专利权人地址： 6-1, Ohtemachi 1-chome Chiyoda-ku, Tokyo-to JP
- 代理机构： Casalonga, Axel
- 优先权： JP83775/83 19830513
- 主分类号： C07D471/18
- IPC分类号： C07D471/18 ; C07D498/22 ; A61K31/495
摘要：
A compound represented by the formula:
wherein R is a hydrogen atom or a lower alkyl group, X is a hydroxymethyl group and Y is a cyano group, and when R is a lower alkyl group, X and Y may combine to form -CH 2 -O-, and salts thereof, process for preparing the same, and an anti-tumor composition containing the same, which is improved in stability in comparison with a starting compound DC-52.
wherein R is a hydrogen atom or a lower alkyl group, X is a hydroxymethyl group and Y is a cyano group, and when R is a lower alkyl group, X and Y may combine to form -CH 2 -O-, and salts thereof, process for preparing the same, and an anti-tumor composition containing the same, which is improved in stability in comparison with a starting compound DC-52.
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