A novel glycerol derivative which is effective to reduce blood pressure has the formula:
wherein R¹ is an alkyl group having 10-22 carbon atoms, R² is lower acyl, benzoyl, aryl, mono-, di- or triaryl­alkyl, alkyl, cycloalkyl, or cycloalkylalkyl; Q is sub­stituted or unsubstituted alkylene containing 1-4 carbon atoms, ℓ is 0 or 1; Y is a nitrogen-containing heterocy­clic group or a nitrogen-containing bridged heterocyclic group (-(Q) ℓ - is attached to a carbon atom contained in a hetero-ring of the heterocyclic group) in which Y is the bridged heterocyclic group where ℓ is 0; and each of R⁵, R⁶ and R⁷ is hydrogen, lower alkyl, aryl or aralkyl.