发明授权
- 专利标题： DNA and polypeptide for tumor-associated antigen CO-029
- 专利标题（中）： DNA和肿瘤相关抗原CO-029的多肽
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申请号： EP91307957.0申请日： 1991-08-30
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公开(公告)号： EP0478146B1公开(公告)日： 1996-04-10
- 发明人: Linnenbach, Alban , Koprowski, Hilary , Szala, Stanislaw
- 申请人： THE WISTAR INSTITUTE
- 申请人地址： 36th Street at Spruce Philadelphia Pennsylvania 19104 US
- 专利权人： THE WISTAR INSTITUTE
- 当前专利权人： THE WISTAR INSTITUTE
- 当前专利权人地址： 36th Street at Spruce Philadelphia Pennsylvania 19104 US
- 代理机构： Dean, John Paul
- 优先权： US575567 19900831
- 主分类号： C12N15/12
- IPC分类号： C12N15/12 ; C12P21/02 ; C07K14/705 ; C07K16/30
摘要：
The human tumor-associated antigen CO-029 is a monoclonal antibody-defined, 27-30 kDa cell surface glycoprotein. A full-length cDNA clone for CO-029 is described. When transiently expressed in COS cells, the cDNA clone direct the synthesis of an antigen reactive with monoclonal antibody CO-029 in mixed hemadsorption and immunoblot assays. Sequence analysis reveals that CO-029 belongs to a family of cell surface antigens which includes the melanoma-associated antigen ME491, the leukocyte cell surface antigen CD37, and the Sm23 antigen of the parasitic helminth Schistosoma mansoni.
公开/授权文献
- EP0478146A1 DNA and polypeptide for tumor-associated antigen CO-029 公开/授权日：1992-04-01
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