- 专利标题： DERIVES ANTIMITOTIQUES DES ALCALOIDES BINAIRES DU CATHARANTHUS ROSEUS
- 专利标题（英）： Novel antimitotic binary alkaloid derivatives extracted from catharanthus roseus
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申请号： EP94922935.5申请日： 1994-07-19
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公开(公告)号： EP0710240B1公开(公告)日： 1996-12-18
- 发明人: JACQUESY, Jean-Claude , FAHY, Jacques , BERRIER, Christian , BIGG, Dennis , JOUANNETAUD, Marie-Paule , ZUNINO, Fabien , KRUCZYNSKI, Anna , KISS, Robert
- 申请人： PIERRE FABRE MEDICAMENT
- 申请人地址： 45, Place Abel Gance 92100 Boulogne FR
- 专利权人： PIERRE FABRE MEDICAMENT
- 当前专利权人： PIERRE FABRE MEDICAMENT
- 当前专利权人地址： 45, Place Abel Gance 92100 Boulogne FR
- 代理机构： Ahner, Francis
- 优先权： FR9308948 19930721
- 国际公布： WO9503312 19950202
- 主分类号： C07D519/04
- IPC分类号： C07D519/04 ; A61K31/475
摘要：
Novel fluorinated derivatives of the vinblastine and vinorelbine family of general formula (1) and the therapeutically acceptable salts of these molecules. The invention also concerns the application of said compounds in therapy and their methods of preparation.
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