发明授权
- 专利标题： VIRUS AUXILIAIRES POUR LA PREPARATION DE VECTEURS VIRAUX RECOMBINANTS
- 专利标题（英）： Helper viruses for preparing recombinant viral vectors
- 专利标题（中）： 辅助病毒重组病毒载体生产
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申请号： EP96927107.1申请日： 1996-07-30
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公开(公告)号： EP0842279B1公开(公告)日： 2001-10-31
- 发明人: LUSKY, Monika , MEHTALI, Majid
- 申请人： TRANSGENE S.A.
- 申请人地址： 11, rue de Molsheim 67000 Strasbourg FR
- 专利权人： TRANSGENE S.A.
- 当前专利权人： TRANSGENE S.A.
- 当前专利权人地址： 11, rue de Molsheim 67000 Strasbourg FR
- 代理机构： Warcoin, Jacques
- 优先权： FR9509289 19950731
- 国际公布： WO9705255 19970213
- 主分类号： C12N15/56
- IPC分类号： C12N15/56 ; C12N7/01 ; C12N5/10 ; A61K48/00
摘要：
Novel helper vectors are provided for complementing defective recombinant viral vectors, characterised in that they are provided with recombination sequences recognised by a recombinase. A complementation cell expressing the recombinase, and a method for preparing recombinant viral vectors as infectious viral particles for transferring and expressing genes of interest in a host organism or cell, are also provided. The invention is particularly suitable for use in gene therapy, especially in humans.
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