发明公开
- 专利标题: RECEPTOR-MEDIATED GENE DELIVERY USING BACTERIOPHAGE VECTORS
- 专利标题(中): 受体介导的基因传输使用噬菌体作为矢量
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申请号: EP98943466.7申请日: 1998-08-28
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公开(公告)号: EP1005377A2公开(公告)日: 2000-06-07
- 发明人: LAROCCA, David , BAIRD, Andrew , JOHNSON, Wendy
- 申请人: Selective Genetics, Inc.
- 申请人地址: 11035 Roselle Street San Diego, CA 92121-1204 US
- 专利权人: Selective Genetics, Inc.
- 当前专利权人: Selective Genetics, Inc.
- 当前专利权人地址: 11035 Roselle Street San Diego, CA 92121-1204 US
- 代理机构: Gowshall, Jonathan Vallance
- 优先权: US920396 19970829
- 国际公布: WO9910014 19990304
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; C12N15/70
摘要:
Filamentous phage particles displaying a ligand on their surface are used to deliver a therapeutic gene to a cell. The ligand is a fusion protein with a phage capsid protein, covalently conjugated to phage particles, or complexed with modified phage particles.
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