发明公开
EP1009819A1 METHODS USING PHAGE DISPLAY FOR SELECTING INTERNALIZING LIGANDS FOR GENE DELIVERY
审中-公开
使用噬菌体展示技术选择用于基因输送的内部配体的方法
- 专利标题: METHODS USING PHAGE DISPLAY FOR SELECTING INTERNALIZING LIGANDS FOR GENE DELIVERY
- 专利标题(中): 使用噬菌体展示技术选择用于基因输送的内部配体的方法
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申请号: EP98942312.4申请日: 1998-08-28
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公开(公告)号: EP1009819A1公开(公告)日: 2000-06-21
- 发明人: LAROCCA, David
- 申请人: Selective Genetics, Inc.
- 申请人地址: 11035 Roselle Street San Diego, CA 92121-1204 US
- 专利权人: Selective Genetics, Inc.
- 当前专利权人: Selective Genetics, Inc.
- 当前专利权人地址: 11035 Roselle Street San Diego, CA 92121-1204 US
- 代理机构: Gowshall, Jonathan Vallance
- 优先权: US57067P 19970829
- 国际公布: WO9910485 19990304
- 主分类号: C12N15/10
- IPC分类号: C12N15/10 ; C07K14/47 ; G01N33/68 ; C12Q1/68 ; C07K14/71
摘要:
A bacteriophage system is presented for selecting internalizing ligands for gene delivery. The bacteriophage carries a reporter or selectable marker and presents a ligand on its surface. More specifically, a library of potential ligands may be screened for the ability to successfully transduce target cells.
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