发明公开
- 专利标题: FURTHER PRO POLYPEPTIDES AND SEQUENCES THEREOF
- 专利标题(中): 进一步的PRO多肽及其序列
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申请号: EP99942557.2申请日: 1999-09-01
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公开(公告)号: EP1144629A2公开(公告)日: 2001-10-17
- 发明人: BAKER, Kevin , GODDARD, Audrey , GURNEY, Austin, L. , SMITH, Victoria , WATANABE, Colin, K. , WOOD, William, I.
- 申请人: Genentech, Inc.
- 申请人地址: 1 DNA Way South San Francisco, CA 94080-4990 US
- 专利权人: Genentech, Inc.
- 当前专利权人: Genentech, Inc.
- 当前专利权人地址: 1 DNA Way South San Francisco, CA 94080-4990 US
- 代理机构: Denison, Christopher Marcus
- 优先权: US106902P 19981103; US106905P 19981103; US106919P 19981103; US106932P 19981103; US106934P 19981103; US107783P 19981110; US108775P 19981117; US108779P 19981117; US108787P 19981117; US108788P 19981117; US108801P 19981117; US108802P 19981117; US108806P 19981117; US108807P 19981117; US108867P 19981117; US108925P 19981117; US108848P 19981118; US108849P 19981118; US108850P 19981118; US108851P 19981118; US108852P 19981118; US108858P 19981118; US108904P 19981118; US98716P 19980901; US98749P 19980901; US98750P 19980901; US98803P 19980902; US98821P 19980902; US98843P 19980902; US99536P 19980909; US99596P 19980909; US99598P 19980909; US99602P 19980909; US99642P 19980909; US99741P 19980910; US99754P 19980910; US99763P 19980910; US99792P 19980910; US99808P 19980910; US99812P 19980910; US99815P 19980910; US99816P 19980910; US100385P 19980915; US100388P 19980915; US100390P 19980915; US100584P 19980916; US100627P 19980916; US100661P 19980916; US100662P 19980916; US100664P 19980916; US100683P 19980917; US100710P 19980917; US100711P 19980917; US100919P 19980917; US100930P 19980917; US100848P 19980918; US100849P 19980918; US101014P 19980918; US101068P 19980918; US101071P 19980918; US101279P 19980922; US101471P 19980923; US101472P 19980923; US101474P 19980923; US101475P 19980923; US101476P 19980923; US101477P 19980923; US101479P 19980923; US101738P 19980924; US101741P 19980924; US101743P 19980924; US101915P 19980924; US101916P 19980924; US102207P 19980929; US102240P 19980929; US102307P 19980929; US102330P 19980929; US102331P 19980929; US102484P 19980930; US102487P 19980930; US102570P 19980930; US102571P 19980930; US102684P 19981001; US102687P 19981001; US102965P 19981002; US103258P 19981006; US103449P 19981006; US103314P 19981007; US103315P 19981007; US103328P 19981007; US103395P 19981007; US103396P 19981007; US103401P 19981007; US103633P 19981008; US103678P 19981008; US103679P 19981008; US103711P 19981008; US104257P 19981014; US104987P 19981020; US105000P 19981020; US105002P 19981020; US105104P 19981021; US105169P 19981022; US105266P 19981022; US105693P 19981026; US105694P 19981026; US105807P 19981027; US105881P 19981027; US105882P 19981027; US106062P 19981027; US106023P 19981028; US106029P 19981028; US106030P 19981028; US106032P 19981028; US106033P 19981028; US106178P 19981028; US106248P 19981029; US106384P 19981029; US108500P 19981029; US106464P 19981030; US106856P 19981103
- 国际公布: WO0012708 20000309
- 主分类号: C12N15/12
- IPC分类号: C12N15/12 ; C07K14/705 ; C12N15/62 ; C07K16/28 ; C12Q1/68 ; C12N5/10
摘要:
Membrane-bound proteins and receptor molecules have various industrial applications, including as pharmaceutical and diagnostic agents. Receptor immunoadhesins, for instance, can be employed as therapeutic agents to block receptor-ligand interactions. The membrane-bound proteins can also be employed for screening of potential peptide or small molecule inhibitors of the relevant receptor/ligand interaction. Efforts are being undertaken by both industry and academia to identify new, native receptor or membrane-bound proteins. Many efforts are focused on the screening of mammalian recombinant DNA libraries to identifiy the coding sequences for novel receptor or membrane-bound proteins. The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
公开/授权文献
- EP1144629A3 FURTHER PRO POLYPEPTIDES AND SEQUENCES THEREOF 公开/授权日:2001-11-28
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