Preventive or therapeutic drugs for dermatitises accompanied with dimorphic inflammatory reactions and those caused by repeated exposure to antigens, which inhibit the progression of such dermatitises and are so safe by virtue of their being free from adverse effects as to bring about enhancement in the quality of daily life of a patient. Specifically, remedies for the above dermatitisescontaining chymase inhibitors as the active ingredient, wherein the chymase inhibitors are quinazoline derivatives of the general formula (I) or (II) or pharmacologically acceptable salts thereof.