发明公开
- 专利标题： HEPATITIS C VIRUS VACCINE
- 专利标题（中）： 丙型肝炎病毒疫苗
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申请号： EP02773740.2申请日： 2002-10-10
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公开(公告)号： EP1436397A2公开(公告)日： 2004-07-14
- 发明人: EMINI, Emilio, A. , KASLOW, David, C. , BETT, Andrew, J. , SHIVER, John, W. , NICOSIA, Alfredo , LAHM, Armin , LUZZAGO, Alessandra , CORTESE, Riccardo , COLLOCA, Stefano
- 申请人： Merck & Co., Inc. , Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A.
- 申请人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 专利权人： Merck & Co., Inc.,Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A.
- 当前专利权人： Merck & Co., Inc.,Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A.
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, NJ 07065-0907 US
- 代理机构： Horgan, James Michael Frederic
- 优先权： US328655P 20011011; US363774P 20020313
- 国际公布： WO2003031588 20030417
- 主分类号： C12N15/40
- IPC分类号： C12N15/40 ; C12N15/51 ; C12N15/85 ; C12N15/86 ; C12N15/861 ; A61K48/00
摘要：
The present invention features Ad6 vectors and a nucleic acid encoding a Met-NS3-NS4A-NS4B-NS5A-NS5B polypeptide containing an inactive NS5B RNA-dependent RNA polymerase region. The nucleic acid is particularly useful as a component of an adenovector or DNA plasmid vaccine providing a broad range of antigens for generating an HCV specific cell mediated immune (CMI) response against HCV.
公开/授权文献
- EP1436397B1 HEPATITIS C VIRUS VACCINE 公开/授权日：2010-05-12
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