专利检索 ap:("Merck & Co., Inc." OR "Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A.") AND inv:"LAHM, Armin" 第 1 页

1.

发明公开
HEPATITIS C VIRUS VACCINE 有权
标题翻译：丙型肝炎病毒疫苗

公开(公告)号：EP1436397A2

公开(公告)日：2004-07-14

申请号：EP02773740.2

申请日：2002-10-10

申请人： Merck & Co., Inc. , Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A.

发明人： EMINI, Emilio, A. , KASLOW, David, C. , BETT, Andrew, J. , SHIVER, John, W. , NICOSIA, Alfredo , LAHM, Armin , LUZZAGO, Alessandra , CORTESE, Riccardo , COLLOCA, Stefano

IPC分类号： C12N15/40 , C12N15/51 , C12N15/85 , C12N15/86 , C12N15/861 , A61K48/00

CPC分类号： C07K14/005 , A61K2039/5256 , A61K2039/53 , A61K2039/545 , A61K2039/57 , C12N15/86 , C12N2710/10343 , C12N2770/24222 , C12N2770/24234 , C12N2800/108 , C12N2810/6018 , C12N2830/003 , C12N2840/20 , C12N2840/203

摘要： The present invention features Ad6 vectors and a nucleic acid encoding a Met-NS3-NS4A-NS4B-NS5A-NS5B polypeptide containing an inactive NS5B RNA-dependent RNA polymerase region. The nucleic acid is particularly useful as a component of an adenovector or DNA plasmid vaccine providing a broad range of antigens for generating an HCV specific cell mediated immune (CMI) response against HCV.