发明公开
EP1453602A4 COMPOSITIONS AND METHODS FOR SEPARATING HETEROCYCLIC AROMATIC AMINE BASES, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEOTIDE SEQUENCES
审中-公开
用于分离芳香杂环组合物和方法基地阿明，核苷，核苷酸和核苷酸
- 专利标题： COMPOSITIONS AND METHODS FOR SEPARATING HETEROCYCLIC AROMATIC AMINE BASES, NUCLEOSIDES, NUCLEOTIDES, AND NUCLEOTIDE SEQUENCES
- 专利标题（中）： 用于分离芳香杂环组合物和方法基地阿明，核苷，核苷酸和核苷酸
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申请号： EP02736754申请日： 2002-05-11
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公开(公告)号： EP1453602A4公开(公告)日： 2005-01-12
- 发明人: BRUENING RONALD L , KRAKOWIAK KRZYSZTOF E , BRUENING MILTON , HAYMORE BARRY L , DEARDEN DAVID VERNELL
- 申请人： IBC ADVANCED TECH INC
- 专利权人： IBC ADVANCED TECH INC
- 当前专利权人： IBC ADVANCED TECH INC
- 优先权： US29057701 2001-05-11; US14424502 2002-05-10
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; B01J20/22 ; C07H1/06 ; C07H19/10 ; C07H19/20 ; C07H21/00 ; C07H21/04 ; C12N15/10
摘要：
The compositions of the present invention comprise one or more palladium bound ligands that are covalently bonded to inorganic or organic solid supports. These palladium bound ligands bonded to solid supports can be used for single heterocyclic amine base separation, or can be used to separate nucleotide chain containing specific sequences from other nucleotides or nucleotide chains. In one aspect of the invention, each ligand present is individually complexed to a single Pd(II)ion. If there are from 2 to 4 ligands present in the composition, then each ligand present must be separated from the other ligands by at least 3 atoms, preferably from 3 to 20 carbon atoms or equivalent spacing.
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