发明公开
- 专利标题: ARYL UREAS WITH ANGIOGENESIS INHIBITING ACTIVITY
- 专利标题(中): 甲苯磺酸索拉非用于治疗疾病的特征在于异常的血管生成
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申请号: EP03707846.6申请日: 2003-02-11
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公开(公告)号: EP1478358A1公开(公告)日: 2004-11-24
- 发明人: DUMAS, Jacques , SCOTT, William, J. , ELTING, James , HATOUM-MAKDAD, Holia
- 申请人: Bayer Pharmaceuticals Corporation
- 申请人地址: 400 Morgan Lane West Haven, CT 06516 US
- 专利权人: Bayer Pharmaceuticals Corporation
- 当前专利权人: Bayer Pharmaceuticals Corporation
- 当前专利权人地址: 400 Morgan Lane West Haven, CT 06516 US
- 代理机构: Ziebig, Marlene K., Dr.
- 优先权: US354950P 20020211
- 国际公布: WO2003068228 20030821
- 主分类号: A61K31/44
- IPC分类号: A61K31/44 ; A61K31/4436 ; A61K31/4725 ; A61K31/4709 ; A61K31/17 ; A61P35/00 ; A61P17/06 ; A61P19/02 ; A61P27/02
摘要:
This invention relates to the use of aryl ureas in the manufacture of a medicament for treating or preventing diseases characterized by abnormal angiogenesis or hyperpermeability processes which are mediated by the VEGF induced signal transduction pathway.
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