公开(公告)号：EP1478358A1

公开(公告)日：2004-11-24

申请号：EP03707846.6

申请日：2003-02-11

申请人： Bayer Pharmaceuticals Corporation

发明人： DUMAS, Jacques ,  SCOTT, William, J. ,  ELTING, James ,  HATOUM-MAKDAD, Holia

IPC分类号： A61K31/44 ,  A61K31/4436 ,  A61K31/4725 ,  A61K31/4709 ,  A61K31/17 ,  A61P35/00 ,  A61P17/06 ,  A61P19/02 ,  A61P27/02

CPC分类号： A61K31/5377 ,  A61K31/17 ,  A61K31/40 ,  A61K31/421 ,  A61K31/426 ,  A61K31/44 ,  A61K31/4436 ,  A61K31/445 ,  A61K31/454 ,  A61K31/4709 ,  A61K31/4725 ,  A61K31/496 ,  A61K31/497 ,  A61K31/54 ,  Y02A50/401 ,  Y02A50/411 ,  Y02A50/414 ,  Y02A50/473

摘要： This invention relates to the use of aryl ureas in the manufacture of a medicament for treating or preventing diseases characterized by abnormal angiogenesis or hyperpermeability processes which are mediated by the VEGF induced signal transduction pathway.