发明授权
- 专利标题: METHOD AND NUCLEIC ACIDS FOR THE ANALYSIS OF A COLON CELL PROLIFERACTIVE DISORDER
- 专利标题(中): 方法和核酸用于分析结肠癌细胞
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申请号: EP03714760.0申请日: 2003-02-27
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公开(公告)号: EP1478778B1公开(公告)日: 2009-05-13
- 发明人: ADORJAN, Peter , BURGER, Matthias , MAIER, Sabine , NIMMRICH, Inko , BECKER, Evelyne , LESCHE, Ralf , RUJAN, Tamas , SCHMITT, Armin
- 申请人: Epigenomics AG
- 申请人地址: Kastanienallee 24 10435 Berlin DE
- 专利权人: Epigenomics AG
- 当前专利权人: Epigenomics AG
- 当前专利权人地址: Kastanienallee 24 10435 Berlin DE
- 代理机构: Krauss, Jan
- 优先权: EP02004551 20020227
- 国际公布: WO2003072821 20030904
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68
摘要:
The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for ascertaining genetic and/or epigenetic parameters of genes for use in the differentiation, diagnosis, treatment and/or monitoring of colon cell proliferative disorders, or the predisposition to colon cell proliferative disorders.
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