发明授权
- 专利标题： DIHYDROPYRIDINE DERIVATIVES
- 专利标题（中）： 二氢吡啶衍生物
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申请号： EP05738155.0申请日： 2005-05-04
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公开(公告)号： EP1879866B1公开(公告)日： 2011-03-16
- 发明人: VAN STRATEN, Nicole, Corine Renee , GERRITSMA, Gerritdina Geziena , VAN DER VEEN, Lars Anders
- 申请人： N.V. Organon
- 申请人地址： Kloosterstraat 6 5349 AB Oss NL
- 专利权人： N.V. Organon
- 当前专利权人： N.V. Organon
- 当前专利权人地址： Kloosterstraat 6 5349 AB Oss NL
- 代理机构： van Wezenbeek, Petrus M.G.F.
- 国际公布： WO2006117023 20061109
- 主分类号： C07D215/54
- IPC分类号： C07D215/54 ; A61K31/47 ; A61P5/06
摘要：
The present invention relates to dihydropyridine derivatives having general formula (I) or a pharmaceutically acceptable salt thereof, wherein R1 is (1-6C)alkyl, (2-6C)alkenyl, (2-6C)alkynyl, phenyl, (1-5C)heteroaryl R2, R3 are independently (1-4C)alkyl, (2-4C)alkenyl, (2-4C)alkynyl, (1-4C)alkoxy, (24C)alkenyloxy, (2-4C)alkynyloxy, halogen X is SO2, CH2, C(O) or X is absent R4 is (1-6C)alkyl, (2-6C)alkenyl, (2-6C)alkynyl, (3-6C)cycloalkyl, (3-6C)cycloalkenyl, (3-6C)cycloalkyl(1-4C)alkyl, (2-6C)heterocycloalkyl, (2-6C)heterocycloalkyl(14C)alkyl, (6-1 OC)aryl, (6-10C)aryl(1-4C)alkyl, (1-9C)heteroaryl or (1-9C)heteroaryl(14C)alkyl. The compounds are useful for the treatment of fertility disorders.
公开/授权文献
- EP1879866A1 DIHYDROPYRIDINE DERIVATIVES 公开/授权日：2008-01-23
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