发明公开
- 专利标题： Polynucleotides related to colon cancer
- 专利标题（中）： 与结肠癌有关的多核苷酸
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申请号： EP08006693.9申请日： 2008-03-31
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公开(公告)号： EP1953243A2公开(公告)日： 2008-08-06
- 发明人: Kennedy, Giulia C. , Kang, Sanmao , Reinhard, Christoph , Jefferson, Anne Bennet
- 申请人： Novartis Vaccines and Diagnostics, Inc.
- 申请人地址： 4560 Horton Street Emeryville, CA 94608 US
- 专利权人： Novartis Vaccines and Diagnostics, Inc.
- 当前专利权人： Novartis Vaccines and Diagnostics, Inc.
- 当前专利权人地址： 4560 Horton Street Emeryville, CA 94608 US
- 代理机构： Hallybone, Huw George
- 优先权： US211835P 20000615
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12N15/11 ; A61K31/00 ; G01N33/574 ; G01N33/68
摘要：
The present invention is based on the discovery of polynucleotides that represent genes that are differentially expressed in colon cancer, e.g., adenomatous polyp, colorectal carcinoma, high metastatic potential colon tumor and metastatic colon cancer. The invention features methods of identifying cells affected by such colon diseases by detection of a gene product encoded by such differentially expressed genes, as well as method of modulating expression of such gene products to effect therapy (e.g., to decrease growth and/or affect abnormal characteristics of cancerous or displastic colon cells).
公开/授权文献
- EP1953243B1 Polynucleotides related to colon cancer 公开/授权日：2012-12-26
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