发明公开
- 专利标题： SYNTHESIS OF SIALIC ACID IN PLANTS
- 专利标题（中）： 唾液酸在植物体内合成
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申请号： EP07710612.8申请日： 2007-02-09
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公开(公告)号： EP1987137A1公开(公告)日： 2008-11-05
- 发明人: PACCALET, Thomas , BARDOR, Muriel , RIHOUEY, Christophe , GOMORD, Véronique , FAYE, Loïc , LEROUGE, Patrice , AQUIN, Stéphanie , VEZINA, Louis-Philippe , D'AOUST, Marc-André
- 申请人： Medicago Inc. , Centre National de la Recherche Scientifique
- 申请人地址： 1020, Route de l'Eglise, bureau 600 Sainte-Foy, QC G1V 3V9 CA
- 专利权人： Medicago Inc.,Centre National de la Recherche Scientifique
- 当前专利权人： Medicago Inc.,Centre National de la Recherche Scientifique
- 当前专利权人地址： 1020, Route de l'Eglise, bureau 600 Sainte-Foy, QC G1V 3V9 CA
- 代理机构： Tombling, Adrian George
- 优先权： US743267P 20060209
- 国际公布： WO2007090290 20070816
- 主分类号： C12N5/10
- IPC分类号： C12N5/10 ; A01H1/00 ; A01H5/00 ; A01H5/10 ; A61K38/14 ; C12N15/54 ; C12N15/60 ; C12N15/82 ; C12N5/04 ; C12N9/88 ; C12N9/90 ; C12P19/02 ; C12P21/00 ; C12N9/10
摘要：
A method of synthesizing sialic acid in plants, and plants capable of synthesizing sialic acid is provided. Furthermore, a method of producing sialylated protein in a plant is also provided. The method to synthesize sialic acid comprises providing a plant comprising a nucleotide sequence encoding N-acetyl neuraminic acid (Neu5Ac) synthase or Neu5Ac lyase, and expressing the nucleotide sequence thereby synthesizing sialic acid. The plant may also co-express a nucleotide sequence encoding one or more than one of an epimerase, a CMP-Neu5Ac synthase, a CMP-Neu5Ac transporter and a sialyltransferase.
公开/授权文献
- EP1987137B1 SYNTHESIS OF SIALIC ACID IN PLANTS 公开/授权日：2011-06-22
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