发明公开
- 专利标题： VERFAHREN ZUR IN-VITRO ÜBERWACHUNG POSTOPERATIVER VERÄNDERUNGEN NACH LEBERTRANSPLANTATION
- 专利标题（英）： Method for in vitro monitoring of postoperative changes following liver transplantation
- 专利标题（中）： 程序的体外监测术后更改后，肝脏移植
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申请号： EP07723651.1申请日： 2007-04-11
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公开(公告)号： EP2032718A2公开(公告)日： 2009-03-11
- 发明人: RUSSWURM, Stefan
- 申请人： SIRS-Lab GmbH
- 申请人地址： Winzerlaer Strasse 2a 07745 Jena DE
- 专利权人： SIRS-Lab GmbH
- 当前专利权人： SIRS-Lab GmbH
- 当前专利权人地址： Winzerlaer Strasse 2a 07745 Jena DE
- 代理机构： Kaiser, Jürgen
- 优先权： DE102006019480 20060426
- 国际公布： WO2007124820 20071108
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
The present invention relates to the use of gene expression profiles, obtained in vitro from a patient sample, for detecting any postoperative tissue incompatibility reactions following a liver transplantation, wherein in patients the gene activity of a plurality of specific genes relevant to a liver transplantation is determined in a patient sample, and the specific genes and/or gene fragments for monitoring of postoperative states are selected from the group consisting of: SEQ-ID No. 1 to SEQ-ID No. 532, these preferably being subdivided into several clusters.
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