发明授权
- 专利标题： PREPARATION CONTAINING HIGHLY PURIFIED BOTULINUM TOXIN TYPE A DERIVED FROM INFANT BOTULISM PATHOGEN
- 专利标题（中）： 制备与纯化的A型肉毒毒素从婴儿期一肉毒中毒剂
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申请号： EP07830661.0申请日： 2007-10-26
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公开(公告)号： EP2085093B1公开(公告)日： 2015-02-25
- 发明人: HARAKAWA, Tetsuhiro , NAKANO, Hirotoshi , TORII, Yasushi , GOTO, Yoshitaka , SHINMURA, Miho , OKUDA, Sachio , KAJI, Ryuji , KOSAKI, Shunji
- 申请人： The Chemo-Sero-Therapeutic Research Institute , The University of Tokushima
- 申请人地址： 1-6-1 Okubo Kita-ku Kumamoto-shi Kumamoto 860-8568 JP
- 专利权人： The Chemo-Sero-Therapeutic Research Institute,The University of Tokushima
- 当前专利权人： The Chemo-Sero-Therapeutic Research Institute,The University of Tokushima
- 当前专利权人地址： 1-6-1 Okubo Kita-ku Kumamoto-shi Kumamoto 860-8568 JP
- 代理机构： Vossius & Partner
- 优先权： JP2006293173 20061027
- 国际公布： WO2008050866 20080502
- 主分类号： A61K38/48
- IPC分类号： A61K38/48 ; A61K47/42 ; A61P1/00 ; A61P7/12 ; A61P17/00 ; A61P21/02 ; A61P25/00 ; A61P25/04 ; A61P25/06 ; A61P25/16 ; A61P27/02 ; A61P43/00
摘要：
A novel type A botulinum toxin preparation is provided. A neuromuscular transmission blocking agent comprising as an active ingredient a highly purified type A botulinum toxin from Clostridium botulinum as infant botulism pathogen and a medicament for treating a disease with a muscle overactivity comprising as an active ingredient said toxin. In particular, the medicament of the present invention, as compared to the conventional known botulinum toxin preparations, has rapid efficacy of potential and is less diffusive and thus, having a broader safety margin, may be used as therapeutic medicament for decreasing local, muscle overactivity in a disease with a muscle overactivity.
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