发明授权
- 专利标题: Remodelling and glycoconjugation of human growth hormone (hGH)
- 专利标题(中): 人类生长激素(hGH)的重塑和糖缀合
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申请号: EP10012938.6申请日: 2002-10-09
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公开(公告)号: EP2279754B1公开(公告)日: 2014-08-13
- 发明人: De Frees, Shawn , Zopf, David , Bayer, Robert , Bowe, Caryn , Hakes, David , Chen, Xi
- 申请人: ratiopharm GmbH
- 申请人地址: Graf-Arco-Strasse 3 89079 Ulm DE
- 专利权人: ratiopharm GmbH
- 当前专利权人: ratiopharm GmbH
- 当前专利权人地址: Graf-Arco-Strasse 3 89079 Ulm DE
- 代理机构: Neuefeind, Regina
- 优先权: US328523P 20011010; US344692P 20011019; US334233P 20011128; US334301P 20011128; US387292P 20020607; US391777P 20020625; US396594P 20020717; US404249P 20020816; US407527P 20020828
- 主分类号: A61K47/48
- IPC分类号: A61K47/48 ; C07K1/00 ; C07K1/13 ; A61K38/14 ; A61K38/16 ; A61K38/24 ; A61K38/26 ; A61K38/28 ; A61K38/29 ; A61K38/30 ; A61K38/43 ; C07K9/00 ; C07K14/475 ; C07K14/59 ; C07K14/61 ; C07K14/525 ; C07K14/56 ; C07K14/565 ; C12N9/64 ; C12N9/22 ; C07K19/00 ; C07K14/79 ; C07H19/10
摘要:
The invention includes methods and compositions for remodelling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group of peptide.
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