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公开(公告)号：EP2305314B1
公开(公告)日：2015-12-23
申请号：EP10012798.4
申请日：2002-10-09
申请人： ratiopharm GmbH
发明人： De Frees, Shawn , Zopf, David , Bayer, Robert , Bowe, Caryn , Hakes, David , Chen, Xi
IPC分类号： A61K47/48 , C07K1/00 , C07K1/13 , A61K38/14 , A61K38/16 , A61K38/24 , A61K38/26 , A61K38/28 , A61K38/29 , A61K38/30 , A61K38/43 , C07K9/00 , C07K14/475 , C07K14/59 , C07K14/61 , C07K14/525 , C07K14/56 , C07K14/565 , C12N9/64 , C12N9/22 , C07K19/00 , C07K14/79 , C07H19/10
CPC分类号： C12N9/2445 , A61K47/549 , A61K47/60 , A61K47/68 , A61K47/6845 , A61K47/6855 , A61K47/6863 , A61K47/6867 , C07K1/006 , C07K1/1077 , C07K1/13 , C07K9/00 , C07K14/505 , C07K14/535 , C07K14/55 , C07K14/56 , C07K14/565 , C07K14/57 , C07K14/59 , C07K14/61 , C07K14/62 , C07K14/7151 , C07K14/755 , C07K14/8125 , C12N9/22 , C12N9/6437 , C12N9/644 , C12N9/6459 , C12N9/6462 , C12Y302/01021 , C12Y304/21021 , C12Y304/21022 , C12Y304/21069 , C12Y304/21073 , Y02A50/472
摘要： The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group a peptide.
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2.发明授权
公开(公告)号：EP2080525B1
公开(公告)日：2015-12-16
申请号：EP09151346.5
申请日：2002-10-09
申请人： ratiopharm GmbH
发明人： De Frees, Shawn , Zopf, David , Bayer, Robert , Bowe, Caryn , Hakes, David , Chen, Xi
IPC分类号： A61K47/48 , C07K1/13 , C07K14/505
CPC分类号： C12N9/6437 , A61K38/00 , A61K47/549 , A61K47/60 , A61K47/68 , A61K47/6845 , A61K47/6855 , A61K47/6863 , A61K47/6867 , C07K1/006 , C07K1/1077 , C07K1/13 , C07K9/00 , C07K14/505 , C07K14/535 , C07K14/55 , C07K14/56 , C07K14/565 , C07K14/57 , C07K14/59 , C07K14/61 , C07K14/62 , C07K14/7151 , C07K14/755 , C07K14/8125 , C12N9/22 , C12N9/2445 , C12N9/644 , C12N9/6459 , C12N9/6462 , C12Y302/01021 , C12Y304/21021 , C12Y304/21022 , C12Y304/21069 , C12Y304/21073 , Y02A50/472
摘要： The invention includes methods and compositions for remodelling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group of peptide.
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3.发明授权
公开(公告)号：EP2338333B1
公开(公告)日：2017-09-06
申请号：EP10012941.0
申请日：2004-04-09
申请人： ratiopharm GmbH
发明人： De Frees, Shawn , Zopf, David , Bayer, Robert , Bowe, Caryn , Hakes, David , Chen, Xi
IPC分类号： A01N43/04
CPC分类号： A61K47/48215 , A61K38/1793 , A61K38/1816 , A61K38/185 , A61K38/193 , A61K38/212 , A61K38/215 , A61K38/24 , A61K38/36 , A61K38/40 , A61K38/465 , A61K38/47 , A61K38/482 , A61K38/4846 , A61K38/57 , A61K39/3955 , A61K47/549 , A61K47/60 , C07K5/1013 , C07K5/1016 , C07K9/00 , C07K9/008 , C07K14/00 , C07K16/241 , C07K2317/24 , C12N9/6424 , C12N9/6437 , C12N9/644 , C12N9/6459 , C12N9/96 , C12P21/005 , C12Y301/27005 , C12Y302/01045 , C12Y304/21021 , C12Y304/21022 , C12Y304/21068
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4.发明授权Remodelling and glycoconjugation of Granulocyte Colony Stimulating Factor (G-CSF) 有权重塑和粒细胞集落的Glykokonjugation刺激因子（G-CSF）
公开(公告)号：EP2042196B1
公开(公告)日：2016-07-13
申请号：EP09000818.6
申请日：2002-10-09
申请人： ratiopharm GmbH
发明人： De Frees, Shawn , Zopf, David , Bayer, Robert , Bowe, Caryn , Hakes, David , Chen, Xi
IPC分类号： A61K47/48 , C07K1/00 , C07K1/13 , A61K38/14 , A61K38/16 , A61K38/24 , A61K38/26 , A61K38/28 , A61K38/29 , A61K38/30 , A61K38/43 , C07K9/00 , C07K14/475 , C07K14/59 , C07K14/61 , C07K14/525 , C07K14/56 , C07K14/565 , C12N9/64 , C12N9/22 , C07K19/00 , C07K14/79 , C07H19/10
CPC分类号： C12N9/6437 , A61K38/00 , A61K47/549 , A61K47/60 , A61K47/68 , A61K47/6845 , A61K47/6855 , A61K47/6863 , A61K47/6867 , C07K1/006 , C07K1/1077 , C07K1/13 , C07K9/00 , C07K14/505 , C07K14/535 , C07K14/55 , C07K14/56 , C07K14/565 , C07K14/57 , C07K14/59 , C07K14/61 , C07K14/62 , C07K14/7151 , C07K14/755 , C07K14/8125 , C12N9/22 , C12N9/2445 , C12N9/644 , C12N9/6459 , C12N9/6462 , C12Y302/01021 , C12Y304/21021 , C12Y304/21022 , C12Y304/21069 , C12Y304/21073 , Y02A50/472
摘要： The invention includes methods and compositions for remodelling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group of peptide.
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5.发明授权Remodelling and glycoconjugation of Fibroblast Growth Factor (FGF) 有权Neumodulierung和成纤维细胞生长因子Glykokonjugation（FGF）
公开(公告)号：EP2279755B1
公开(公告)日：2014-02-26
申请号：EP10012939.4
申请日：2002-10-09
申请人： ratiopharm GmbH
发明人： De Frees, Shawn , Zopf, David , Bayer, Robert , Bowe, Caryn , Hakes, David , Chen, Xi
IPC分类号： A61K47/48 , C07K1/00 , C07K1/13 , A61K38/14 , A61K38/16 , A61K38/24 , A61K38/26 , A61K38/28 , A61K38/29 , A61K38/30 , A61K38/43 , C07K9/00 , C07K14/475 , C07K14/59 , C07K14/61 , C07K14/525 , C07K14/56 , C07K14/565 , C12N9/64 , C12N9/22 , C07K19/00 , C07K14/79 , C07H19/10
CPC分类号： C12N9/6437 , A61K38/00 , A61K47/549 , A61K47/60 , A61K47/68 , A61K47/6845 , A61K47/6855 , A61K47/6863 , A61K47/6867 , C07K1/006 , C07K1/1077 , C07K1/13 , C07K9/00 , C07K14/505 , C07K14/535 , C07K14/55 , C07K14/56 , C07K14/565 , C07K14/57 , C07K14/59 , C07K14/61 , C07K14/62 , C07K14/7151 , C07K14/755 , C07K14/8125 , C12N9/22 , C12N9/2445 , C12N9/644 , C12N9/6459 , C12N9/6462 , C12Y302/01021 , C12Y304/21021 , C12Y304/21022 , C12Y304/21069 , C12Y304/21073 , Y02A50/472
摘要： The invention includes methods and compositions for remodelling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group of peptide.
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公开(公告)号：EP2279754B1
公开(公告)日：2014-08-13
申请号：EP10012938.6
申请日：2002-10-09
申请人： ratiopharm GmbH
发明人： De Frees, Shawn , Zopf, David , Bayer, Robert , Bowe, Caryn , Hakes, David , Chen, Xi
IPC分类号： A61K47/48 , C07K1/00 , C07K1/13 , A61K38/14 , A61K38/16 , A61K38/24 , A61K38/26 , A61K38/28 , A61K38/29 , A61K38/30 , A61K38/43 , C07K9/00 , C07K14/475 , C07K14/59 , C07K14/61 , C07K14/525 , C07K14/56 , C07K14/565 , C12N9/64 , C12N9/22 , C07K19/00 , C07K14/79 , C07H19/10
CPC分类号： C12N9/6437 , A61K38/00 , A61K47/549 , A61K47/60 , A61K47/68 , A61K47/6845 , A61K47/6855 , A61K47/6863 , A61K47/6867 , C07K1/006 , C07K1/1077 , C07K1/13 , C07K9/00 , C07K14/505 , C07K14/535 , C07K14/55 , C07K14/56 , C07K14/565 , C07K14/57 , C07K14/59 , C07K14/61 , C07K14/62 , C07K14/7151 , C07K14/755 , C07K14/8125 , C12N9/22 , C12N9/2445 , C12N9/644 , C12N9/6459 , C12N9/6462 , C12Y302/01021 , C12Y304/21021 , C12Y304/21022 , C12Y304/21069 , C12Y304/21073 , Y02A50/472
摘要： The invention includes methods and compositions for remodelling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group of peptide.
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公开(公告)号：EP2305313B1
公开(公告)日：2014-03-26
申请号：EP10012797.6
申请日：2002-10-09
申请人： ratiopharm GmbH
发明人： De Frees, Shawn , Zopf, David , Bayer, Robert , Bowe, Caryn , Hakes, David , Chen, Xi
IPC分类号： A61K47/48 , C07K1/00 , C07K1/13 , A61K38/14 , A61K38/16 , A61K38/24 , A61K38/26 , A61K38/28 , A61K38/29 , A61K38/30 , A61K38/43 , C07K9/00 , C07K14/475 , C07K14/59 , C07K14/61 , C07K14/525 , C07K14/56 , C07K14/565 , C12N9/64 , C12N9/22 , C07K19/00 , C07K14/79 , C07H19/10
CPC分类号： C12N9/2445 , A61K47/549 , A61K47/60 , A61K47/68 , A61K47/6845 , A61K47/6855 , A61K47/6863 , A61K47/6867 , C07K1/006 , C07K1/1077 , C07K1/13 , C07K9/00 , C07K14/505 , C07K14/535 , C07K14/55 , C07K14/56 , C07K14/565 , C07K14/57 , C07K14/59 , C07K14/61 , C07K14/62 , C07K14/7151 , C07K14/755 , C07K14/8125 , C12N9/22 , C12N9/6437 , C12N9/644 , C12N9/6459 , C12N9/6462 , C12Y302/01021 , C12Y304/21021 , C12Y304/21022 , C12Y304/21069 , C12Y304/21073 , Y02A50/472
摘要： The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group a peptide.
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公开(公告)号：EP2298354B1
公开(公告)日：2014-03-19
申请号：EP10012796.8
申请日：2002-10-09
申请人： ratiopharm GmbH
发明人： De Frees, Shawn , Zopf, David , Bayer, Robert , Bowe, Caryn , Hakes, David , Chen, Xi
IPC分类号： A61K47/48 , C07K1/00 , C07K1/13 , A61K38/14 , A61K38/16 , A61K38/24 , A61K38/26 , A61K38/28 , A61K38/29 , A61K38/30 , A61K38/43 , C07K9/00 , C07K14/475 , C07K14/59 , C07K14/61 , C07K14/525 , C07K14/56 , C07K14/565 , C12N9/64 , C12N9/22 , C07K19/00 , C07K14/79 , C07H19/10
CPC分类号： C12N9/2445 , A61K47/549 , A61K47/60 , A61K47/68 , A61K47/6845 , A61K47/6855 , A61K47/6863 , A61K47/6867 , C07K1/006 , C07K1/1077 , C07K1/13 , C07K9/00 , C07K14/505 , C07K14/535 , C07K14/55 , C07K14/56 , C07K14/565 , C07K14/57 , C07K14/59 , C07K14/61 , C07K14/62 , C07K14/7151 , C07K14/755 , C07K14/8125 , C12N9/22 , C12N9/6437 , C12N9/644 , C12N9/6459 , C12N9/6462 , C12Y302/01021 , C12Y304/21021 , C12Y304/21022 , C12Y304/21069 , C12Y304/21073 , Y02A50/472
摘要： The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group a peptide.
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公开(公告)号：EP2305312B1
公开(公告)日：2015-03-04
申请号：EP10012794.3
申请日：2002-10-09
申请人： ratiopharm GmbH
发明人： De Frees, Shawn , Zopf, David , Bayer, Robert , Bowe, Caryn , Hakes, David , Chen, Xi
IPC分类号： A61K47/48 , C07K1/00 , C07K1/13 , A61K38/14 , A61K38/16 , A61K38/24 , A61K38/26 , A61K38/28 , A61K38/29 , A61K38/30 , A61K38/43 , C07K9/00 , C07K14/475 , C07K14/59 , C07K14/61 , C07K14/525 , C07K14/56 , C07K14/565 , C12N9/64 , C12N9/22 , C07K19/00 , C07K14/79 , C07H19/10
CPC分类号： C12N9/2445 , A61K47/549 , A61K47/60 , A61K47/68 , A61K47/6845 , A61K47/6855 , A61K47/6863 , A61K47/6867 , C07K1/006 , C07K1/1077 , C07K1/13 , C07K9/00 , C07K14/505 , C07K14/535 , C07K14/55 , C07K14/56 , C07K14/565 , C07K14/57 , C07K14/59 , C07K14/61 , C07K14/62 , C07K14/7151 , C07K14/755 , C07K14/8125 , C12N9/22 , C12N9/6437 , C12N9/644 , C12N9/6459 , C12N9/6462 , C12Y302/01021 , C12Y304/21021 , C12Y304/21022 , C12Y304/21069 , C12Y304/21073 , Y02A50/472
摘要： The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group a peptide.
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