发明公开
EP2325298A2 Simian adenoviruses SAdV-36, -42.1, -42.2, AND -44 and uses thereof
有权
丝棉SADV-36，-42.1，-42.2，-44和及其使用
- 专利标题： Simian adenoviruses SAdV-36, -42.1, -42.2, AND -44 and uses thereof
- 专利标题（中）： 丝棉SADV-36，-42.1，-42.2，-44和及其使用
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申请号： EP10186684.6申请日： 2009-03-03
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公开(公告)号： EP2325298A2公开(公告)日： 2011-05-25
- 发明人: Wilson, James M. , Vandenberghe, Luk , Roy, Soumitra
- 申请人： The Trustees of The University of Pennsylvania
- 申请人地址： 3160 Chestnut Street, Suite 200 Philadelphia, Pennsylvania 19104-6283 US
- 专利权人： The Trustees of The University of Pennsylvania
- 当前专利权人： The Trustees of The University of Pennsylvania
- 当前专利权人地址： 3160 Chestnut Street, Suite 200 Philadelphia, Pennsylvania 19104-6283 US
- 代理机构： Manaton, Ross Timothy
- 优先权： US67993P 20080304; US68027P 20080304; US68024P 20080304; US68069P 20080304
- 主分类号： C12N7/00
- IPC分类号： C12N7/00
摘要：
An adenovirus is disclosed, having a capsid comprising a hexon protein of SAdV-42.1 or an amino acid sequence at least about 99% identical thereto, or a hybrid hexon protein. The capsid encapsidates a heterologous nucleic acid molecule carrying a gene sequence operably linked to expression control sequences which direct transcription, translation, and/or expression in a host cell, and further encapsidates 5' and 3' adenovirus cis-elements necessary for replication and encapsidation.
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