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公开(公告)号：EP2774985B1
公开(公告)日：2016-12-14
申请号：EP14162957.6
申请日：2009-10-29
IPC分类号： C12N7/00 , C12N15/861
CPC分类号： C12N15/86 , C12N2710/10321 , C12N2710/10322 , C12N2710/10341 , C12N2710/10342 , C12N2710/10343 , C12N2710/10345 , C12N2710/10352 , C12N2810/6018
摘要： A recombinant vector comprises simian adenovirus 43, 45, 46, 47, 48, 49 or 50 sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses simian adenovirus 43, 45, 46, 47, 48, 49 or 50 gene(s) is also disclosed. Methods of using the vectors and cell lines are provided.
摘要翻译： 重组载体包含猿猴腺病毒43,45,46,47,48,49或50个序列，以及在调节序列控制下的异源基因。 还公开了表达猿腺病毒43,45,46,47,48,49或50个基因的细胞系。 提供了使用载体和细胞系的方法。
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2.发明公开Simian adenoviruses SAdV-36, -42.1, -42.2, AND -44 and uses thereof 有权丝棉SADV-36，-42.1，-42.2，-44和及其使用
公开(公告)号：EP2325298A3
公开(公告)日：2012-08-29
申请号：EP10186684.6
申请日：2009-03-03
IPC分类号： C12N7/00
CPC分类号： C12N7/00 , A61K35/761 , A61K39/145 , A61K2039/5256 , A61K2039/57 , C07K14/005 , C12N15/86 , C12N2710/10321 , C12N2710/10322 , C12N2710/10343 , C12N2710/10371 , C12N2760/16122 , C12N2760/16134 , C12N2760/16171
摘要： An adenovirus is disclosed, having a capsid comprising a hexon protein of SAdV-42.1 or an amino acid sequence at least about 99% identical thereto, or a hybrid hexon protein. The capsid encapsidates a heterologous nucleic acid molecule carrying a gene sequence operably linked to expression control sequences which direct transcription, translation, and/or expression in a host cell, and further encapsidates 5' and 3' adenovirus cis-elements necessary for replication and encapsidation.
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3.发明授权Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use 有权猿猴腺病毒核酸和氨基酸序列，含有它们的载体和使用方法
公开(公告)号：EP2301582B1
公开(公告)日：2017-07-12
申请号：EP10178464.3
申请日：2002-11-20
发明人： Wilson, James M. , Gao, Guangping , Roy, Soumitra
IPC分类号： A61K47/42 , C07H21/00 , C07K14/075 , C12N7/00 , C12N15/33 , C12N15/861
CPC分类号： A61K39/235 , A61K39/00 , A61K48/00 , A61K2039/525 , A61K2039/5256 , A61K2039/57 , C07K14/005 , C12N7/00 , C12N15/86 , C12N2710/10022 , C12N2710/10321 , C12N2710/10322 , C12N2710/10343 , C12N2710/10362 , C12N2710/20022 , C12N2740/16122 , C12N2740/17022 , C12N2750/14122 , C12N2760/14134 , C12N2760/16134 , C12N2760/20122 , C12N2830/002 , C12N2830/55
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4.发明公开Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use 有权由其衍生的猴的腺病毒载体的核酸和氨基酸序列，和使用方法
公开(公告)号：EP2301582A1
公开(公告)日：2011-03-30
申请号：EP10178464.3
申请日：2002-11-20
发明人： Wilson, James M. , Gao, Guangping , Roy, Soumitra
IPC分类号： A61K47/42 , C07H21/00 , C07K14/075 , C12N7/00 , C12N15/33 , C12N15/861
CPC分类号： A61K39/235 , A61K39/00 , A61K48/00 , A61K2039/525 , A61K2039/5256 , A61K2039/57 , C07K14/005 , C12N7/00 , C12N15/86 , C12N2710/10022 , C12N2710/10321 , C12N2710/10322 , C12N2710/10343 , C12N2710/10362 , C12N2710/20022 , C12N2740/16122 , C12N2740/17022 , C12N2750/14122 , C12N2760/14134 , C12N2760/16134 , C12N2760/20122 , C12N2830/002 , C12N2830/55
摘要： A recombinant vector comprises simian adenovirus sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses simian adenovirus gene(s) is also disclosed. Methods of using the vectors and cell lines are provided.
摘要翻译： 一种重组载体，包括猿猴腺病毒序列和调控序列的控制下的异源基因。 的细胞系快车哪个猿猴腺病毒基因IST游离缺失盘。 提供了使用所述载体和细胞系的方法。
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公开(公告)号：EP2463362B1
公开(公告)日：2017-11-08
申请号：EP12158503.8
申请日：2008-11-24
IPC分类号： C12N7/00 , C07K14/075 , C12N15/861
CPC分类号： C12N7/00 , C12N2710/10321 , C12N2710/10322 , C12N2710/10343
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6.发明公开Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use 审中-公开猿猴腺病毒的核酸和氨基酸序列衍生的载体和使用方法。
公开(公告)号：EP1944043A1
公开(公告)日：2008-07-16
申请号：EP08003966.2
申请日：2002-11-20
发明人： Wilson, James, M. , Gao, Guangping , Roy, Soumitra
IPC分类号： A61K47/42 , C07H21/00 , C07K14/075 , C12N7/00 , C12N15/33 , C12N15/861
CPC分类号： C12N15/86 , A61K39/00 , A61K48/00 , A61K2039/5256 , A61K2039/57 , C07K14/005 , C12N7/00 , C12N2710/10322 , C12N2710/10343 , C12N2710/10362 , C12N2760/14122 , C12N2760/14134 , C12N2830/002 , C12N2830/55
摘要： A recombinant vector comprises simian adenovirus sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses simian adenovirus gene(s) is also disclosed. Methods of using the vectors and cell lines are provided.
摘要翻译： 一种重组载体，包括猿猴腺病毒序列和调控序列的控制下的异源基因。 的细胞系快车哪个猿猴腺病毒基因IST游离缺失盘。 提供了使用所述载体和细胞系的方法。
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公开(公告)号：EP2774985A1
公开(公告)日：2014-09-10
申请号：EP14162957.6
申请日：2009-10-29
IPC分类号： C12N7/00 , C12N15/861
CPC分类号： C12N15/86 , C12N2710/10321 , C12N2710/10322 , C12N2710/10341 , C12N2710/10342 , C12N2710/10343 , C12N2710/10345 , C12N2710/10352 , C12N2810/6018
摘要： A recombinant vector comprises simian adenovirus 43, 45, 46, 47, 48, 49 or 50 sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses simian adenovirus 43, 45, 46, 47, 48, 49 or 50 gene(s) is also disclosed. Methods of using the vectors and cell lines are provided.
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8.发明公开Simian subfamily c adenovirus SAdv-31 and uses thereof 有权Adenovirus SAdV-31 der Affen-Unterfamilie C und Verwendungen davon
公开(公告)号：EP2463362A1
公开(公告)日：2012-06-13
申请号：EP12158503.8
申请日：2008-11-24
IPC分类号： C12N7/00 , C07K14/075 , C12N15/861 , C07K14/005 , C12N15/86
CPC分类号： C12N7/00 , C12N2710/10321 , C12N2710/10322 , C12N2710/10343
摘要： A recombinant vector comprises simian adenovirus SAdV-31 sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses simian adenovirus SAdV-31 gene(s) is also disclosed. Methods of using the vectors and cell lines are provided.
摘要翻译： 重组载体包含猿猴腺病毒SAdV-31序列和在调节序列控制下的异源基因。 还公开了表达猿猴腺病毒SAdV-31基因的细胞系。 提供使用载体和细胞系的方法。
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9.发明公开Simian adenoviruses SAdV-36, -42.1, -42.2, AND -44 and uses thereof 有权丝棉SADV-36，-42.1，-42.2，-44和及其使用
公开(公告)号：EP2325298A2
公开(公告)日：2011-05-25
申请号：EP10186684.6
申请日：2009-03-03
IPC分类号： C12N7/00
CPC分类号： C12N7/00 , A61K35/761 , A61K39/145 , A61K2039/5256 , A61K2039/57 , C07K14/005 , C12N15/86 , C12N2710/10321 , C12N2710/10322 , C12N2710/10343 , C12N2710/10371 , C12N2760/16122 , C12N2760/16134 , C12N2760/16171
摘要： An adenovirus is disclosed, having a capsid comprising a hexon protein of SAdV-42.1 or an amino acid sequence at least about 99% identical thereto, or a hybrid hexon protein. The capsid encapsidates a heterologous nucleic acid molecule carrying a gene sequence operably linked to expression control sequences which direct transcription, translation, and/or expression in a host cell, and further encapsidates 5' and 3' adenovirus cis-elements necessary for replication and encapsidation.
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10.发明公开Simian adenovirus nucleic acid and amino acid sequences, vectors containing same, and methods of use 审中-公开猿猴腺病毒的核酸和氨基酸序列衍生的载体和使用方法。
公开(公告)号：EP2286841A1
公开(公告)日：2011-02-23
申请号：EP10178483.3
申请日：2002-11-20
发明人： Wilson, James M. , Gao, Guangping , Roy, Soumitra
IPC分类号： A61K47/42 , C07H21/00 , C07K14/075 , C12N7/00 , C12N15/33 , C12N15/861
CPC分类号： A61K39/235 , A61K39/00 , A61K48/00 , A61K2039/525 , A61K2039/5256 , A61K2039/57 , C07K14/005 , C12N7/00 , C12N15/86 , C12N2710/10022 , C12N2710/10321 , C12N2710/10322 , C12N2710/10343 , C12N2710/10362 , C12N2710/20022 , C12N2740/16122 , C12N2740/17022 , C12N2750/14122 , C12N2760/14134 , C12N2760/16134 , C12N2760/20122 , C12N2830/002 , C12N2830/55
摘要： A recombinant vector comprises simian adenovirus sequences and a heterologous gene under the control of regulatory sequences. A cell line which expresses simian adenovirus gene(s) is also disclosed. Methods of using the vectors and cell lines are provided.
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