发明公开
EP2328928A2 CONSERVED INFLUENZA HEMAGGLUTININ EPITOPE AND ANTIBODIES THERETO
审中-公开
KONSERVIERTESINFLUENZAHÄMAGGLUTININEPITOPUNDANTIKÖRPERDAGEGEN
- 专利标题: CONSERVED INFLUENZA HEMAGGLUTININ EPITOPE AND ANTIBODIES THERETO
- 专利标题(中): KONSERVIERTESINFLUENZAHÄMAGGLUTININEPITOPUNDANTIKÖRPERDAGEGEN
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申请号: EP09791906.2申请日: 2009-08-25
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公开(公告)号: EP2328928A2公开(公告)日: 2011-06-08
- 发明人: MARASCO, Wayne, A. , SUI, Jianhua , LIDDINGTON, Robert, C.
- 申请人: Dana-Farber Cancer Institute, Inc. , Burnham Institute for Medical Research
- 申请人地址: 450 Brookline Avenue Boston, MA 02115 US
- 专利权人: Dana-Farber Cancer Institute, Inc.,Burnham Institute for Medical Research
- 当前专利权人: Dana-Farber Cancer Institute, Inc.,Burnham Institute for Medical Research
- 当前专利权人地址: 450 Brookline Avenue Boston, MA 02115 US
- 代理机构: Ireland, Jacqueline Frances
- 优先权: US91599P 20080825; US154400P 20090222; US150231P 20090205
- 国际公布: WO2010027818 20100311
- 主分类号: C07K16/10
- IPC分类号: C07K16/10 ; C07K14/11 ; A61K39/145 ; G01N33/50
摘要:
Disclosed are antibodies that bind to the stem region of influenza hemagglutinin in the neutral pH conformation, hemagglutinin epitopes in the stem region, and methods of making and using both.
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