INFLUENZA VIRUS VACCINES AND USES THEREOF
    8.
    发明公开

    公开(公告)号:EP3900740A1

    公开(公告)日:2021-10-27

    申请号:EP21153235.3

    申请日:2011-03-30

    摘要: The invention provides hemagglutinin stem domain polypeptides, nucleic acids encoding the same, host cells expressing the same and viruses comprising the same. The invention also provides a viral-like particle comprising the polypeptides of the invention. The invention further provides immunogenic compositions comprising the polypeptides, viruses or viral-like particles of the invention. The invention also provides immunogenic compositions for use in immunizing a subject against influenza virus, and for use in preventing and treating an influenza virus infection or disease.