发明公开
- 专利标题： Use of a PCV2 immunogenic composition for lessening clinical symptoms in pigs
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申请号： EP11164855.6申请日： 2006-12-28
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公开(公告)号： EP2374475A1公开(公告)日： 2011-10-12
- 发明人: Roof, Michael B. , Hayes, Phillip Wayne , Eichmeyer, Marc , Nitzel, Greg , Schaeffer, Merrill
- 申请人： BOEHRINGER INGELHEIM VETMEDICA, INC.
- 申请人地址： 2621 North Belt Highway St. Joseph MO 64506-2002 US
- 专利权人： BOEHRINGER INGELHEIM VETMEDICA, INC.
- 当前专利权人： BOEHRINGER INGELHEIM VETMEDICA, INC.
- 当前专利权人地址： 2621 North Belt Highway St. Joseph MO 64506-2002 US
- 代理机构： Hammann, Heinz
- 优先权： US755016P 20051229; US829809P 20061017
- 主分类号： A61K39/12
- IPC分类号： A61K39/12
摘要：
The present invention relates to the use of an immunogenic composition that comprises a porcine circovirus type 2 (PCV2) antigen for treatment of several clinical manifestations (diseases). Preferably, the clinical manifestations are associated with a PCV2 infection. Preferably, they include lymphadenopathy, lymphoid depletion and/or multinucleated/giant histiocytes. Moreover, the clinical symptoms include lymphadenopathy in combination with one or a multiple of the following symptoms in pigs: (1) interstitial pneumonia with interlobular edema, (2) cutaneous pallor or icterus, (3) mottled atrophic livers, (4) gastric ulcers, (5) nephritis and (6) reproductive disorders, e.g. abortion, stillbirths, mummies, etc. Furthermore the clinical symptoms include Pia like lesions, normally known to be associated with Lawsonia intracellularis infections.
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