发明公开
EP2471901A1 METHOD FOR PRODUCING T CELL POPULATION UNDER PRESENCE OF RETINOIC ACID
审中-公开
VERFAHREN ZUR HERSTELLUNG EINER T-ZELLEN人口统计VERWENDUNG VON RETINSURE
- 专利标题： METHOD FOR PRODUCING T CELL POPULATION UNDER PRESENCE OF RETINOIC ACID
- 专利标题（中）： VERFAHREN ZUR HERSTELLUNG EINER T-ZELLEN人口统计VERWENDUNG VON RETINSURE
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申请号： EP10811841.5申请日： 2010-08-24
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公开(公告)号： EP2471901A1公开(公告)日： 2012-07-04
- 发明人: KATAYAMA, Yoshinori , SAKAI, Kensuke , YOSHIOKA, Hirofumi , TAKAKURA, Hikaru , CHONO, Hideto , SAITO, Naoki , MINENO, Junichi
- 申请人： Takara Bio, Inc.
- 申请人地址： 4-1, Seta 3-chome Otsu-shi Shiga 520-2193 JP
- 专利权人： Takara Bio, Inc.
- 当前专利权人： Takara Bio, Inc.
- 当前专利权人地址： 4-1, Seta 3-chome Otsu-shi Shiga 520-2193 JP
- 代理机构： Zwicker, Jörk
- 优先权： JP2009194444 20090825; JP2009287258 20091218
- 国际公布： WO2011024791 20110303
- 主分类号： C12N5/00
- IPC分类号： C12N5/00 ; C12N5/07 ; C12N5/10 ; C07K14/78
摘要：
Disclosed is a method for producing a cell population containing memory-like T cells, said method being characterized by including a step for in vitro culturing of a cell population containing T cells or T cell precursor cells using a retinoic acid and a CD3 ligand. Further disclosed is a method for producing a cell population wherein the proportion of memory-like T cells is increased and wherein a desired gene is introduced with a high efficiency and is highly expressed.
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