发明公开
- 专利标题： MODULATION OF HUNTINGTIN EXPRESSION
- 专利标题（中）： 调制表达亨廷顿的
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申请号： EP10816206申请日： 2010-09-10
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公开(公告)号： EP2475675A4公开(公告)日： 2013-05-15
- 发明人: HUNG GENE , BENNETT C FRANK , FREIER SUSAN M , KORDASIEWICZ HOLLY , STANEK LISA , CLEVELAND DON W , CHENG SENG H , SHIHABUDDIN LAMYA
- 申请人： ISIS PHARMACEUTICALS INC
- 专利权人： ISIS PHARMACEUTICALS INC
- 当前专利权人： ISIS PHARMACEUTICALS INC
- 优先权： US24185309 2009-09-11
- 主分类号： C12N15/113
- IPC分类号： C12N15/113 ; A61K31/712 ; A61K31/7125
摘要：
Provided herein are methods, compounds, and compositions for reducing expression of huntingtin mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate Huntington's disease, or a symptom thereof.
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