发明公开
EP2475722A1 NOVEL PHOTOACTIVABLE FLUORESCENT DYES FOR OPTICAL MICROSCOPY AND IMAGING TECHNIQUES
有权
新的光激活荧光探针用于光学显微镜和成像过程
- 专利标题： NOVEL PHOTOACTIVABLE FLUORESCENT DYES FOR OPTICAL MICROSCOPY AND IMAGING TECHNIQUES
- 专利标题（中）： 新的光激活荧光探针用于光学显微镜和成像过程
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申请号： EP09778459.9申请日： 2009-09-10
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公开(公告)号： EP2475722A1公开(公告)日： 2012-07-18
- 发明人: HELL, Stefan , BELOV, Vladimir, N. , BOYARSKIY, Vadim, P. , WURM, Christian , JAKOBS, Stefan , GEISLER, Claudia
- 申请人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
- 申请人地址： Hofgartenstraße 8 80539 München DE
- 专利权人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
- 当前专利权人： Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
- 当前专利权人地址： Hofgartenstraße 8 80539 München DE
- 代理机构： Katzameyer, Michael
- 国际公布： WO2011029459 20110317
- 主分类号： C09B3/12
- IPC分类号： C09B3/12 ; C09B3/20 ; C09B3/24 ; G01N33/58
摘要：
The present invention relates to novel photoactivable rhodamine or carbopyronine derivatives of the following general formulae G1-G4 (I), G1: A1 = O, A2 = N, A3 = C; G2: A1 = S, A2 = N, A3 = C; G3: A1 = O, A2 = O, A3 = N; G4: A1 = S, A2 = O, A3 = N; comprising UV light absorbing chromophores which after photolysis by irradiation at 254-490 nm (preferably at 375-420 nm) generate fluorescent rhodamine or carbopyronine derivatives and small non-toxic fragments such as N
2 or N
2 O. The invention also relates to methods for preparing such compounds and to the use of these compounds for optical microscopy and imaging techniques.
2 or N
2 O. The invention also relates to methods for preparing such compounds and to the use of these compounds for optical microscopy and imaging techniques.
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