发明授权
EP2493894B1 AZABICYCLIC COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS
有权
AYABICYCLISCHE化合物如α-7烟碱乙酰胆碱REZPETORLIGANDEN
- 专利标题： AZABICYCLIC COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS
- 专利标题（中）： AYABICYCLISCHE化合物如α-7烟碱乙酰胆碱REZPETORLIGANDEN
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申请号： EP10776869.9申请日： 2010-10-26
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公开(公告)号： EP2493894B1公开(公告)日： 2014-01-29
- 发明人: MCDONALD, Ivar M. , MATE, Robert A. , COOK II, James H. , KING, Dalton , OLSON, Richard E. , WANG, Nenghui , IWUAGWU, Christiana I. , ZUSI, Christopher, F. , MACOR, John E.
- 申请人： Bristol-Myers Squibb Company
- 申请人地址： Route 206 and Province Line Road Princeton, NJ 05843-4000 US
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： Route 206 and Province Line Road Princeton, NJ 05843-4000 US
- 代理机构： Reitstötter - Kinzebach
- 优先权： US255794P 20091028
- 国际公布： WO2011056573 20110512
- 主分类号： C07D498/20
- IPC分类号： C07D498/20 ; C07D519/00 ; A61K31/55 ; A61P25/18 ; A61P25/28
摘要：
The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic alpha7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.
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