发明公开
- 专利标题: ANTIBODIES DIRECTED AGAINST IL-17
- 专利标题(中): 抗体与人IL-17
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申请号: EP11815158.8申请日: 2011-08-02
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公开(公告)号: EP2601217A2公开(公告)日: 2013-06-12
- 发明人: HORLICK, Robert , KING, David , BOWERS, Peter , DALTON, Jennifer , WU, Betty , ROBERTS, Traci , ZHANG, Xue , ALTOBELL III, Laurence
- 申请人: AnaptysBio, Inc.
- 申请人地址: 10835 Road to the Cure, Suite 100 San Diego, CA 92121 US
- 专利权人: AnaptysBio, Inc.
- 当前专利权人: AnaptysBio, Inc.
- 当前专利权人地址: 10835 Road to the Cure, Suite 100 San Diego, CA 92121 US
- 代理机构: Hoeger, Stellrecht & Partner Patentanwälte
- 优先权: US370978P 20100805
- 国际公布: WO2012018767 20120209
- 主分类号: C07K16/00
- IPC分类号: C07K16/00 ; A61K39/395 ; C12N15/00 ; C12N5/16 ; C12P21/06
摘要:
The disclosure relates to an isolated IL-17-binding agent which comprises an immunoglobulin heavy chain polypeptide comprising SEQ ID NO: 1 and optionally an immunoglobulin light chain polypeptide comprising SEQ ID NO: 23, except that one or more specific of residues of SEQ ID NO: 1 and SEQ ID NO: 23 are replaced with a different residue. The disclosure also provides vectors, compositions, and methods of using the IL-17-binding agent to treat an IL-17-mediated disease.
公开/授权文献
- EP2601217B1 ANTIBODIES DIRECTED AGAINST IL-17 公开/授权日:2017-06-14
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